2GVD
Complex Of Gs- With The Catalytic Domains Of Mammalian Adenylyl Cyclase: Complex With TNP-ATP and Mn
Summary for 2GVD
Entry DOI | 10.2210/pdb2gvd/pdb |
Related | 1TL7 1U0H |
Descriptor | Adenylate cyclase type 5, Adenylate cyclase type 2, Guanine nucleotide-binding protein G(s), alpha subunit, ... (9 entities in total) |
Functional Keywords | adenylyl cyclase, gsa, tnp-atp, lyase |
Biological source | Canis lupus familiaris (dog) More |
Cellular location | Cell membrane ; Multi-pass membrane protein : P30803 Membrane ; Multi-pass membrane protein : P26769 Cell membrane ; Lipid-anchor : P04896 |
Total number of polymer chains | 3 |
Total formula weight | 97021.58 |
Authors | Mou, T.-C.,Sprang, S.R. (deposition date: 2006-05-02, release date: 2006-07-04, Last modification date: 2023-08-30) |
Primary citation | Mou, T.-C.,Gille, A.,Suryanarayana, S.,Richter, M.,Seifert, R.,Sprang, S.R. Broad specificity of Mammalian adenylyl cyclase for interaction with 2',3'-substituted purine- and pyrimidine nucleotide inhibitors. Mol.Pharmacol., 70:878-886, 2006 Cited by PubMed: 16766715DOI: 10.1124/mol.106.026427 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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