4BIN
| Crystal structure of the E. coli N-acetylmuramoyl-L-alanine amidase AmiC | Descriptor: | N-ACETYLMURAMOYL-L-ALANINE AMIDASE AMIC, SODIUM ION, ZINC ION | Authors: | Kerff, F, Rocaboy, M, Herman, R, Sauvage, E, Charlier, P. | Deposit date: | 2013-04-12 | Release date: | 2013-08-21 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | The Crystal Structure of the Cell Division Amidase Amic Reveals the Fold of the Amin Domain, a New Peptidoglycan Binding Domain. Mol.Microbiol., 90, 2013
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2WGV
| Crystal structure of the OXA-10 V117T mutant at pH 6.5 inhibited by a chloride ion | Descriptor: | BETA-LACTAMASE OXA-10, CHLORIDE ION, CITRIC ACID, ... | Authors: | Vercheval, L, Kerff, F, Bauvois, C, Sauvage, E, Guiet, R, Charlier, P, Galleni, M. | Deposit date: | 2009-04-27 | Release date: | 2010-05-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Three Factors that Modulate the Activity of Class D Beta-Lactamases and Interfere with the Post- Translational Carboxylation of Lys70. Biochem.J., 432, 2010
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2WGW
| Crystal structure of the OXA-10 V117T mutant at pH 8.0 | Descriptor: | BETA-LACTAMASE OXA-10, GLYCEROL, SULFATE ION | Authors: | Vercheval, L, Kerff, F, Bauvois, C, Sauvage, E, Guiet, R, Charlier, P, Galleni, M. | Deposit date: | 2009-04-27 | Release date: | 2010-05-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Three Factors that Modulate the Activity of Class D Beta-Lactamases and Interfere with the Post-Translational Carboxylation of Lys70. Biochem.J., 432, 2010
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2WGI
| Crystal structure of the acyl-enzyme OXA-10 W154A-benzylpenicillin at pH 6 | Descriptor: | BETA-LACTAMASE OXA-10, GLYCEROL, OPEN FORM - PENICILLIN G | Authors: | Vercheval, L, Falzone, C, Sauvage, E, Herman, R, Charlier, P, Galleni, M, Kerff, F. | Deposit date: | 2009-04-20 | Release date: | 2009-11-10 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Critical Role of Tryptophan 154 for the Activity and Stability of Class D Beta-Lactamases. Biochemistry, 48, 2009
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2WKI
| Crystal structure of the OXA-10 K70C mutant at pH 7.0 | Descriptor: | 1,2-ETHANEDIOL, BETA-LACTAMASE OXA-10, GLYCEROL, ... | Authors: | Vercheval, L, Bauvois, C, Kerff, F, Sauvage, E, Guiet, R, Charlier, P, Galleni, M. | Deposit date: | 2009-06-11 | Release date: | 2010-08-25 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Three Factors that Modulate the Activity of Class D Beta-Lactamases and Interfere with the Post-Translational Carboxylation of Lys70. Biochem.J., 432, 2010
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2WKH
| Crystal structure of the acyl-enzyme OXA-10 K70C-Ampicillin at pH 7 | Descriptor: | (2R,4S)-2-[(R)-{[(2R)-2-amino-2-phenylacetyl]amino}(carboxy)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, BETA-LACTAMASE OXA-10, SULFATE ION | Authors: | Vercheval, L, Bauvois, C, Kerff, F, Sauvage, E, Guiet, R, Charlier, P, Galleni, M. | Deposit date: | 2009-06-11 | Release date: | 2010-08-25 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.791 Å) | Cite: | Three Factors that Modulate the Activity of Class D Beta-Lactamases and Interfere with the Post-Translational Carboxylation of Lys70. Biochem.J., 432, 2010
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2WUQ
| Crystal structure of BlaB protein from Streptomyces cacaoi | Descriptor: | BETA-LACTAMASE REGULATORY PROTEIN BLAB, GLYCEROL | Authors: | Dandois, S, Herman, R, Sauvage, E, Charlier, P, Joris, B, Kerff, F. | Deposit date: | 2009-10-07 | Release date: | 2010-10-13 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The Crystal Structure of Blab Protein from Streptomyces Cacaoi To be Published
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2X02
| CRYSTAL STRUCTURE OF THE CLASS D BETA-LACTAMASE OXA-10 AT 1.35 A RESOLUTION | Descriptor: | BETA-LACTAMASE OXA-10, DIMETHYL SULFOXIDE, GLYCEROL, ... | Authors: | Vercheval, L, Kerff, F, Sauvage, E, Herman, R, Galleni, M, Charlier, P. | Deposit date: | 2009-12-04 | Release date: | 2010-12-08 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Impact of the Carboxylated Lysine on the Acylation and Deacylation Step in Class D Beta-Lactamase To be Published
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2X01
| CRYSTAL STRUCTURE OF THE OXA-10 S67A MUTANT AT PH 7 | Descriptor: | BETA-LACTAMASE OXA-10, DIMETHYL SULFOXIDE, SULFATE ION, ... | Authors: | Vercheval, L, Kerff, F, Bauvois, C, Sauvage, E, Guiet, R, Galleni, M, Charlier, P. | Deposit date: | 2009-12-04 | Release date: | 2010-12-08 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Evidence of Chloride Inhibition and Impact of the Hydrophobic Core on the Lysine Carboxylated in Class D Beta-Lactamase To be Published
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2XDM
| Crystal structure of a complex between Actinomadura R39 DD peptidase and a peptidoglycan mimetic boronate inhibitor | Descriptor: | (D-ALPHA-AMINOPIMELYLAMINO)-D-1-ETHYLBORONIC ACID, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, COBALT (II) ION, ... | Authors: | Rocaboy, M, Sauvage, E, Herman, R, Kerff, F, Charlier, P. | Deposit date: | 2010-05-04 | Release date: | 2010-07-21 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal Structure of a Complex between the Actinomadura R39 Dd-Peptidase and a Peptidoglycan- Mimetic Boronate Inhibitor: Interpretation of a Transition State Analogue in Terms of Catalytic Mechanism. Biochemistry, 49, 2010
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2Y91
| Crystal structure of class A beta-lactamase from Bacillus licheniformis BS3 with clavulanic acid | Descriptor: | 5-HYDROXY-3-OXOPENTANOIC ACID, BETA-LACTAMASE, CITRIC ACID, ... | Authors: | Power, P, Sauvage, E, Herman, R, Kerff, F, Charlier, P. | Deposit date: | 2011-02-11 | Release date: | 2012-02-22 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Novel Fragments of Clavulanate Observed in the Structure of the Class a Beta-Lactamase from Bacillus Licheniformis Bs3. J.Antimicrob.Chemother., 67, 2012
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3ZNY
| Crystal structure of the class A extended-spectrum beta-lactamase CTX- M-96, a natural D240G mutant derived from CTX-M-12 | Descriptor: | CTX-M-12A ENZYME | Authors: | Power, P, Herman, R, Bouillenne, F, Ghiglione, B, Rodriguez, M.M, Galleni, M, Gutkind, G, Charlier, P, Sauvage, E. | Deposit date: | 2013-02-18 | Release date: | 2014-01-08 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Structural and Kinetic Insights Into the "Ceftazidimase" Behavior of the Extended-Spectrum Beta-Lactamase Ctx-M-96. Biochemistry, 54, 2015
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3ZNT
| Crystal structure of OXA-24 class D beta-lactamase with tazobactam | Descriptor: | BETA-LACTAMASE, SULFATE ION, TAZOBACTAM INTERMEDIATE | Authors: | Power, P, Sauvage, E, Herman, R, Kerff, F, Charlier, P. | Deposit date: | 2013-02-18 | Release date: | 2014-01-08 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal Structure of Oxa-24 Beta-Lactamase Inhibited by Tazobactam To be Published
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4A5R
| Crystal structure of class A beta-lactamase from Bacillus licheniformis BS3 with tazobactam | Descriptor: | BETA-LACTAMASE, CARBON DIOXIDE, CITRIC ACID, ... | Authors: | Power, P, Sauvage, E, Herman, R, Kerff, F, Charlier, P. | Deposit date: | 2011-10-28 | Release date: | 2012-10-10 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structure of Class a Beta-Lactamase from Bacillus Licheniformis Inhibited by Tazobactam To be Published
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4BZG
| Crystal structure of galactose mutarotase GalM from Bacillus subtilis in complex with maltose | Descriptor: | ALDOSE 1-EPIMERASE, CITRIC ACID, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Vanden Broeck, A, Sauvage, E, Herman, R, Kerff, F, Duez, C, Charlier, P. | Deposit date: | 2013-07-25 | Release date: | 2014-08-13 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.13 Å) | Cite: | Crystal Structure of Galactose Mutarotase Galm from Bacillus Subtilis in Complex with Maltose To be Published
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4BZH
| Crystal structure of galactose mutarotase GalM from Bacillus subtilis in complex with maltose and trehalose | Descriptor: | ALDOSE 1-EPIMERASE, CITRIC ACID, GLYCEROL, ... | Authors: | Vanden Broeck, A, Sauvage, E, Herman, R, Kerff, F, Duez, C, Charlier, P. | Deposit date: | 2013-07-25 | Release date: | 2014-08-13 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal Structure of Galactose Mutarotase Galm from Bacillus Subtilis in Complex with Maltose and Trehalose To be Published
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4BZF
| Crystal structure of galactose mutarotase GalM from Bacillus subtilis with trehalose | Descriptor: | ACETATE ION, ALDOSE 1-EPIMERASE, CITRIC ACID, ... | Authors: | Vanden Broeck, A, Sauvage, E, Herman, R, Kerff, F, Duez, C, Charlier, P. | Deposit date: | 2013-07-25 | Release date: | 2014-08-13 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal Structure of Galactose Mutarotase Galm from Bacillus Subtilis with Trehalose To be Published
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4BZE
| Crystal structure of galactose mutarotase GalM from Bacillus subtilis | Descriptor: | ALDOSE 1-EPIMERASE, CITRIC ACID, GLYCEROL | Authors: | Vanden Broeck, A, Sauvage, E, Herman, R, Kerff, F, Duez, C, Charlier, P. | Deposit date: | 2013-07-25 | Release date: | 2014-08-13 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of Galactose Mutarotase Galm from Bacillus Subtilis To be Published
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4D2O
| Crystal structure of the class A extended-spectrum beta-lactamase PER- 2 | Descriptor: | PER-2 BETA-LACTAMASE | Authors: | Power, P, Herman, R, Ruggiero, M, Kerff, F, Galleni, M, Gutkind, G, Charlier, P, Sauvage, E. | Deposit date: | 2014-05-12 | Release date: | 2014-05-21 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structure of the Extended-Spectrum Beta-Lactamase Per- 2 and Insights Into the Role of Specific Residues in the Interaction with Beta-Lactams and Beta-Lactamase Inhibitors. Antimicrob.Agents Chemother., 58, 2014
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3BEC
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3BEB
| Crystal structure of E. coli penicillin-binding protein 5 in complex with a peptide-mimetic penicillin | Descriptor: | (2R,4S)-2-[(1R)-1-{[(6S)-6-amino-6-carboxyhexanoyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, GLYCEROL, Penicillin-binding protein 5 | Authors: | Heilemann, J, Powell, A.J, Davies, C. | Deposit date: | 2007-11-16 | Release date: | 2008-08-26 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structures of complexes of bacterial DD-peptidases with peptidoglycan-mimetic ligands: the substrate specificity puzzle J.Mol.Biol., 381, 2008
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3TVL
| Complex between the human thiamine triphosphatase and triphosphate | Descriptor: | 1,2-ETHANEDIOL, TRIPHOSPHATE, Thiamine-triphosphatase | Authors: | Delvaux, D, Herman, R, Sauvage, E, Wins, P, Bettendorff, L, Charlier, P, Kerff, F. | Deposit date: | 2011-09-20 | Release date: | 2012-10-10 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural determinants of specificity and catalytic mechanism in mammalian 25-kDa thiamine triphosphatase. Biochim.Biophys.Acta, 1830, 2013
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7AP7
| Structure of the W64R amyloidogenic variant of human lysozyme | Descriptor: | Lysozyme C, SULFATE ION | Authors: | Vettore, N, Herman, R, Kerff, F, Charlier, P, Sauvage, E, Brans, A, Morray, J, Dobson, C, Kumita, J, Dumoulin, M. | Deposit date: | 2020-10-16 | Release date: | 2021-08-25 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Characterisation of the structural, dynamic and aggregation properties of the W64R amyloidogenic variant of human lysozyme. Biophys.Chem., 271, 2021
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4M3K
| Structure of a single domain camelid antibody fragment cAb-H7S in complex with the BlaP beta-lactamase from Bacillus licheniformis | Descriptor: | Beta-lactamase, CHLORIDE ION, Camelid heavy-chain antibody variable fragment cAb-H7S | Authors: | Pain, C, Kerff, F, Herman, R, Sauvage, E, Preumont, S, Charlier, P, Dumoulin, M. | Deposit date: | 2013-08-06 | Release date: | 2014-08-06 | Method: | X-RAY DIFFRACTION (1.48 Å) | Cite: | Probing the mechanism of aggregation of polyQ model proteins with camelid heavy-chain antibody fragments To be Published
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4M3J
| Structure of a single-domain camelid antibody fragment cAb-H7S specific of the BlaP beta-lactamase from Bacillus licheniformis | Descriptor: | Camelid heavy-chain antibody variable fragment cAb-H7S, SULFATE ION | Authors: | Pain, C, Kerff, F, Herman, R, Sauvage, E, Preumont, S, Charlier, P, Dumoulin, M. | Deposit date: | 2013-08-06 | Release date: | 2014-08-06 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Probing the mechanism of aggregation of polyQ model proteins with camelid heavy-chain antibody fragments To be Published
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