3BEB
Crystal structure of E. coli penicillin-binding protein 5 in complex with a peptide-mimetic penicillin
Summary for 3BEB
Entry DOI | 10.2210/pdb3beb/pdb |
Related | 3BEC |
Descriptor | Penicillin-binding protein 5, (2R,4S)-2-[(1R)-1-{[(6S)-6-amino-6-carboxyhexanoyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, GLYCEROL, ... (4 entities in total) |
Functional Keywords | peptidoglycan synthesis, penicillin-binding protein, dd-carboxypeptidase, hydrolase, designed penicillin, cell shape, cell wall biogenesis/degradation, inner membrane, membrane, protease |
Biological source | Escherichia coli |
Cellular location | Cell inner membrane; Peripheral membrane protein; Cytoplasmic side: P0AEB2 |
Total number of polymer chains | 1 |
Total formula weight | 40308.65 |
Authors | Heilemann, J.,Powell, A.J.,Davies, C. (deposition date: 2007-11-16, release date: 2008-08-26, Last modification date: 2023-08-30) |
Primary citation | Sauvage, E.,Powell, A.J.,Heilemann, J.,Josephine, H.R.,Charlier, P.,Davies, C.,Pratt, R.F. Crystal structures of complexes of bacterial DD-peptidases with peptidoglycan-mimetic ligands: the substrate specificity puzzle J.Mol.Biol., 381:383-393, 2008 Cited by PubMed: 18602645DOI: 10.1016/j.jmb.2008.06.012 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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