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6NIU
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BU of 6niu by Molmil
Crystal structure of a human anti-ZIKV-DENV neutralizing antibody MZ4 in complex with ZIKV E glycoprotein
Descriptor: Envelope protein E, Human MZ4 Fab heavy chain, Human MZ4 Fab light chain
Authors:Sankhala, R.S, Dussupt, V, Donofrio, G, Choe, M, Modjarrad, K, Michael, N.L, Krebs, S.J, Joyce, M.G.
Deposit date:2018-12-31
Release date:2019-12-25
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (4.303 Å)
Cite:Potent Zika and dengue cross-neutralizing antibodies induced by Zika vaccination in a dengue-experienced donor.
Nat. Med., 26, 2020
6NIS
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BU of 6nis by Molmil
Crystal structure of a human anti-ZIKV-DENV neutralizing antibody MZ24 isolated following ZPIV vaccination
Descriptor: CHLORIDE ION, GLYCEROL, MZ24 antibody heavy chain, ...
Authors:Sankhala, R.S, Dussupt, V, Donofrio, G, Choe, M, Modjarrad, K, Michael, N.L, Krebs, S.J, Joyce, M.G.
Deposit date:2018-12-31
Release date:2019-12-25
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.113 Å)
Cite:Potent Zika and dengue cross-neutralizing antibodies induced by Zika vaccination in a dengue-experienced donor.
Nat Med, 26, 2020
6MTY
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BU of 6mty by Molmil
Crystal structure of a human anti-ZIKV-DENV neutralizing antibody MZ4 isolated following ZPIV vaccination
Descriptor: MZ4 Heavy Chain, MZ4 Light Chain
Authors:Sankhala, R.S, Dussupt, V, Donofrio, G, Choe, M, Modjarrad, K, Michael, N.L, Krebs, S.J, Joyce, M.G.
Deposit date:2018-10-22
Release date:2019-12-25
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.951 Å)
Cite:Potent Zika and dengue cross-neutralizing antibodies induced by Zika vaccination in a dengue-experienced donor.
Nat Med, 26, 2020
6MTX
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BU of 6mtx by Molmil
Crystal structure of a human anti-ZIKV-DENV neutralizing antibody MZ1 isolated following ZPIV vaccination
Descriptor: GLYCEROL, MZ1 Heavy Chain, MZ1 Light Chain
Authors:Sankhala, R.S, Dussupt, V, Donofrio, G, Choe, M, Modjarrad, K, Michael, N.L, Krebs, S.J, Joyce, M.G.
Deposit date:2018-10-22
Release date:2019-12-25
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.051 Å)
Cite:Potent Zika and dengue cross-neutralizing antibodies induced by Zika vaccination in a dengue-experienced donor.
Nat Med, 26, 2020
6NIP
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BU of 6nip by Molmil
Crystal structure of a human anti-ZIKV-DENV neutralizing antibody MZ1 in complex with ZIKV E glycoprotein
Descriptor: Envelope protein E, MZ1 Heavy chain, MZ1 Light Chain
Authors:Sankhala, R.S, Dussupt, V, Donofrio, G, Choe, M, Modjarrad, K, Michael, N.L, Krebs, S.J, Joyce, M.G.
Deposit date:2018-12-31
Release date:2019-12-25
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (4.16 Å)
Cite:Potent Zika and dengue cross-neutralizing antibodies induced by Zika vaccination in a dengue-experienced donor.
Nat Med, 26, 2020
7N4J
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BU of 7n4j by Molmil
Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing human antibody WRAIR-2173.
Descriptor: Spike protein S1, WRAIR-2173 antibody Fab heavy chain, WRAIR-2173 antibody Fab light chain, ...
Authors:Sankhala, R.S, Joyce, M.G.
Deposit date:2021-06-04
Release date:2021-10-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.207 Å)
Cite:Low-dose in vivo protection and neutralization across SARS-CoV-2 variants by monoclonal antibody combinations.
Nat.Immunol., 22, 2021
7N4I
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BU of 7n4i by Molmil
Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing human antibody WRAIR-2057.
Descriptor: GLYCEROL, Spike protein S1, WRAIR-2057 Antibody Fab Heavy Chain, ...
Authors:Sankhala, R.S, Joyce, M.G.
Deposit date:2021-06-04
Release date:2021-10-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.284 Å)
Cite:Low-dose in vivo protection and neutralization across SARS-CoV-2 variants by monoclonal antibody combinations.
Nat.Immunol., 22, 2021
7N4M
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BU of 7n4m by Molmil
Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing human antibody WRAIR-2151.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, WRAIR-2151 antibody Fab heavy chain, ...
Authors:Sankhala, R.S, Joyce, M.G.
Deposit date:2021-06-04
Release date:2021-11-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.79 Å)
Cite:Low-dose in vivo protection and neutralization across SARS-CoV-2 variants by monoclonal antibody combinations.
Nat.Immunol., 22, 2021
7N4L
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BU of 7n4l by Molmil
Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing human antibody WRAIR-2125.
Descriptor: Spike protein S1, WRAIR-2125 antibody Fab heavy chain, WRAIR-2125 antibody Fab light chain
Authors:Sankhala, R.S, Joyce, M.G.
Deposit date:2021-06-04
Release date:2021-11-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.601 Å)
Cite:Low-dose in vivo protection and neutralization across SARS-CoV-2 variants by monoclonal antibody combinations.
Nat.Immunol., 22, 2021
4ZKP
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BU of 4zkp by Molmil
P22 Tail Needle Gp26 crystallized at pH 7.0
Descriptor: CALCIUM ION, CHLORIDE ION, Tail needle protein gp26
Authors:Sankhala, R.S, Cingolani, G.
Deposit date:2015-04-30
Release date:2015-07-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Plasticity of the Protein Plug That Traps Newly Packaged Genomes in Podoviridae Virions.
J.Biol.Chem., 291, 2016
4ZKU
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BU of 4zku by Molmil
P22 Tail Needle Gp26 crystallized at pH 10.0
Descriptor: CALCIUM ION, CHLORIDE ION, Tail needle protein gp26
Authors:Sankhala, R.S, Cingolani, G.
Deposit date:2015-04-30
Release date:2015-06-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Plasticity of the Protein Plug That Traps Newly Packaged Genomes in Podoviridae Virions.
J.Biol.Chem., 291, 2016
4ZXQ
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BU of 4zxq by Molmil
P22 Tail Needle Gp26 1-140 crystallized at pH 3.9
Descriptor: CALCIUM ION, CHLORIDE ION, Tail needle protein gp26
Authors:Sankhala, R.S, Cingolani, G.
Deposit date:2015-05-20
Release date:2015-08-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural Plasticity of the Protein Plug That Traps Newly Packaged Genomes in Podoviridae Virions.
J.Biol.Chem., 291, 2016
5BU8
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BU of 5bu8 by Molmil
HK620 Tail Needle crystallized at pH 7.5 and derivatized with Xenon
Descriptor: CALCIUM ION, DNA stabilization protein, XENON
Authors:Sankhala, R.S, Cingolani, G.
Deposit date:2015-06-03
Release date:2015-11-25
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.202 Å)
Cite:Structural Plasticity of the Protein Plug That Traps Newly Packaged Genomes in Podoviridae Virions.
J.Biol.Chem., 291, 2016
5V5P
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BU of 5v5p by Molmil
Structure of NLS2R of influenza A virus nucleoprotein bound to importin alpha
Descriptor: Importin subunit alpha-1, Nucleoprotein
Authors:Sankhala, R.S, Lokareddy, R.K, Cingolani, G.
Deposit date:2017-03-14
Release date:2018-03-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Synergy of two low-affinity NLSs determines the high avidity of influenza A virus nucleoprotein NP for human importin alpha isoforms.
Sci Rep, 7, 2017
5V5O
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BU of 5v5o by Molmil
Structure of NLS2K of influenza A virus nucleoprotein bound to importin alpha
Descriptor: Importin subunit alpha-1, Nucleoprotein
Authors:Sankhala, R.S, Lokareddy, R.K, Cingolani, G.
Deposit date:2017-03-14
Release date:2018-03-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.243 Å)
Cite:Synergy of two low-affinity NLSs determines the high avidity of influenza A virus nucleoprotein NP for human importin alpha isoforms.
Sci Rep, 7, 2017
5JJ3
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BU of 5jj3 by Molmil
Refined Structure of the Mature Virion Conformation of P22 Portal Protein
Descriptor: Portal protein
Authors:Lokareddy, R.K, Sankhala, R.S, Cingolani, G.
Deposit date:2016-04-22
Release date:2017-02-08
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (7 Å)
Cite:Portal protein functions akin to a DNA-sensor that couples genome-packaging to icosahedral capsid maturation.
Nat Commun, 8, 2017
8EOO
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BU of 8eoo by Molmil
Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing human antibodies WRAIR-2063 and WRAIR-2151
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Spike protein S1, ...
Authors:Jensen, J.L, Sankhala, R.S, Joyce, M.G.
Deposit date:2022-10-03
Release date:2023-06-14
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:Targeting the Spike Receptor Binding Domain Class V Cryptic Epitope by an Antibody with Pan-Sarbecovirus Activity.
J.Virol., 97, 2023
7S83
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BU of 7s83 by Molmil
Crystal structure of SARS CoV-2 Spike Receptor Binding Domain in complex with shark neutralizing VNARs ShAb01 and ShAb02
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ShAb01 VNAR, ...
Authors:Chen, W.-H, Hajduczki, A, Dooley, H.M, Joyce, M.G.
Deposit date:2021-09-17
Release date:2022-11-23
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Shark nanobodies with potent SARS-CoV-2 neutralizing activity and broad sarbecovirus reactivity.
Nat Commun, 14, 2023
5JJ1
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BU of 5jj1 by Molmil
Structure of the Immature Procapsid Conformation of P22 Portal Protein
Descriptor: Portal protein
Authors:Lokareddy, R.K, Cingolani, G.
Deposit date:2016-04-22
Release date:2017-02-08
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Portal protein functions akin to a DNA-sensor that couples genome-packaging to icosahedral capsid maturation.
Nat Commun, 8, 2017
5BU5
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BU of 5bu5 by Molmil
HK620 Tail Needle crystallized at pH 9 (crystal form I)
Descriptor: CALCIUM ION, CHLORIDE ION, DNA stabilization protein
Authors:Bhardwaj, A, Cingolani, G.
Deposit date:2015-06-03
Release date:2015-06-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.952 Å)
Cite:Structural Plasticity of the Protein Plug That Traps Newly Packaged Genomes in Podoviridae Virions.
J.Biol.Chem., 291, 2016
5BVZ
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BU of 5bvz by Molmil
HK620 Tail Needle crystallized at pH 9 (Crystal form II)
Descriptor: CALCIUM ION, CHLORIDE ION, DNA stabilization protein
Authors:Bhardwaj, A, Cingolani, G.
Deposit date:2015-06-05
Release date:2015-06-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Plasticity of the Protein Plug That Traps Newly Packaged Genomes in Podoviridae Virions.
J.Biol.Chem., 291, 2016
7LFC
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BU of 7lfc by Molmil
Structure of importin a3 bound to p50 NLS
Descriptor: Importin subunit alpha-3, Nuclear factor NF-kappa-B p105 subunit
Authors:Florio, T.J, Lokareddy, R.K, Cingolani, G.
Deposit date:2021-01-16
Release date:2022-01-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Differential recognition of canonical NF-kappa B dimers by Importin alpha 3.
Nat Commun, 13, 2022
7LF4
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BU of 7lf4 by Molmil
Structure of importin a3 bound to the p50- and p65-NLSs
Descriptor: Importin subunit alpha-3, Nuclear factor NF-kappa-B p105 subunit, Transcription factor p65
Authors:Florio, T.J, Lokareddy, R.K, Cingolani, G.
Deposit date:2021-01-15
Release date:2022-01-19
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Differential recognition of canonical NF-kappa B dimers by Importin alpha 3.
Nat Commun, 13, 2022
7LET
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BU of 7let by Molmil
Structure of importin a2 bound to the p50- and p65-NLSs
Descriptor: Importin subunit alpha-1, Nuclear factor NF-kappa-B p105 subunit, Transcription factor p65
Authors:Florio, T.J, Lokareddy, R.K, Cingolani, G.
Deposit date:2021-01-15
Release date:2022-01-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Differential recognition of canonical NF-kappa B dimers by Importin alpha 3.
Nat Commun, 13, 2022
7LEQ
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BU of 7leq by Molmil
Structure of importin a2 bound to p50 NLS
Descriptor: Importin subunit alpha-1, Nuclear factor NF-kappa-B p105 subunit
Authors:Florio, T.J, Lokareddy, R.K, Cingolani, G.
Deposit date:2021-01-14
Release date:2022-01-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Differential recognition of canonical NF-kappa B dimers by Importin alpha 3.
Nat Commun, 13, 2022

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