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7B4T
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BU of 7b4t by Molmil
Broadly neutralizing DARPin bnD.1 in complex with the HIV-1 envelope variable loop 3 crown mimetic peptide V3-IF (BG505)
Descriptor: Broadly neutralizing DARPin bnD.1, HIV-1 envelope variable loop 3 crown mimetic peptide V3-IF (BG505), SULFATE ION
Authors:Friedrich, N, Stiegeler, E, Glogl, M, Lemmin, T, Hansen, S, Kadelka, C, Wu, Y, Ernst, P, Maliqi, L, Foulkes, C, Morin, M, Eroglu, M, Liechti, T, Ivan, B, Reinberg, T, Schaefer, J, Karakus, U, Ursprung, S, Mann, A, Rusert, P, Kouyos, R.D, Robinson, J.A, Gunthard, H.F, Pluckthun, A, Trkola, A.
Deposit date:2020-12-02
Release date:2021-11-24
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Distinct conformations of the HIV-1 V3 loop crown are targetable for broad neutralization.
Nat Commun, 12, 2021
7B4W
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Broadly neutralizing DARPin bnD.3 in complex with the HIV-1 envelope variable loop 3 crown mimetic peptide V3-IF (BG505)
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Broadly neutralizing DARPin bnD.3, ...
Authors:Friedrich, N, Stiegeler, E, Glogl, M, Lemmin, T, Hansen, S, Kadelka, C, Wu, Y, Ernst, P, Maliqi, L, Foulkes, C, Morin, M, Eroglu, M, Liechti, T, Ivan, B, Reinberg, T, Schaefer, J, Karakus, U, Ursprung, S, Mann, A, Rusert, P, Kouyos, R.D, Robinson, J.A, Gunthard, H.F, Pluckthun, A, Trkola, A.
Deposit date:2020-12-02
Release date:2021-11-24
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Distinct conformations of the HIV-1 V3 loop crown are targetable for broad neutralization.
Nat Commun, 12, 2021
7B4V
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BU of 7b4v by Molmil
Broadly neutralizing DARPin bnD.2 in complex with the HIV-1 envelope variable loop 3 crown mimetic peptide V3-IF (BG505)
Descriptor: Broadly neutralizing DARPin bnD.2, CHLORIDE ION, HIV-1 envelope variable loop 3 crown mimetic peptide V3-IF (BG505), ...
Authors:Friedrich, N, Stiegeler, E, Glogl, M, Lemmin, T, Hansen, S, Kadelka, C, Wu, Y, Ernst, P, Maliqi, L, Foulkes, C, Morin, M, Eroglu, M, Liechti, T, Ivan, B, Reinberg, T, Schaefer, J, Karakus, U, Ursprung, S, Mann, A, Rusert, P, Kouyos, R.D, Robinson, J.A, Gunthard, H.F, Pluckthun, A, Trkola, A.
Deposit date:2020-12-02
Release date:2021-11-24
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Distinct conformations of the HIV-1 V3 loop crown are targetable for broad neutralization.
Nat Commun, 12, 2021
7B4U
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Broadly neutralizing DARPin bnD.2 in complex with the HIV-1 envelope variable loop 3 crown mimetic peptide V3-IF (BG505)
Descriptor: Broadly neutralizing DARPin bnD.2, CALCIUM ION, HIV-1 envelope variable loop 3 crown mimetic peptide V3-IF (BG505)
Authors:Friedrich, N, Stiegeler, E, Glogl, M, Lemmin, T, Hansen, S, Kadelka, C, Wu, Y, Ernst, P, Maliqi, L, Foulkes, C, Morin, M, Eroglu, M, Liechti, T, Ivan, B, Reinberg, T, Schaefer, J, Karakus, U, Ursprung, S, Mann, A, Rusert, P, Kouyos, R.D, Robinson, J.A, Gunthard, H.F, Pluckthun, A, Trkola, A.
Deposit date:2020-12-02
Release date:2021-11-24
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Distinct conformations of the HIV-1 V3 loop crown are targetable for broad neutralization.
Nat Commun, 12, 2021
2A9X
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BU of 2a9x by Molmil
TAR RNA recognition by a cyclic peptidomimetic of Tat protein
Descriptor: BIV TAR RNA, BIV-2 cyclic peptide
Authors:Leeper, T.C, Athanassiou, Z, Dias, R.L, Robinson, J.A, Varani, G.
Deposit date:2005-07-12
Release date:2005-11-01
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:TAR RNA recognition by a cyclic peptidomimetic of Tat protein.
Biochemistry, 44, 2005
1LG9
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BU of 1lg9 by Molmil
Crystal structure of OxyB, a Cytochrome P450 Implicated in an Oxidative Phenol Coupling Reaction During Vancomycin Biosynthesis
Descriptor: P450 monooxygenase, PROTOPORPHYRIN IX CONTAINING FE
Authors:Pylypenko, O, Zerbe, K, Vitali, F, Zhang, W, Vrijbloed, J.W, Robinson, J.A, Schlichting, I.
Deposit date:2002-04-15
Release date:2002-12-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of OxyB, a Cytochrome P450 Implicated in an Oxidative Phenol Coupling Reaction during Vancomycin Biosynthesis.
J.Biol.Chem., 277, 2002
1LGF
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BU of 1lgf by Molmil
Crystal structure of OxyB, a Cytochrome P450 Implicated in an Oxidative Phenol Coupling Reaction During Vancomycin Biosynthesis
Descriptor: P450 monooxygenase, PROTOPORPHYRIN IX CONTAINING FE
Authors:Pylypenko, O, Zerbe, K, Vitali, F, Zhang, W, Vrijbloed, J.W, Robinson, J.A, Schlichting, I.
Deposit date:2002-04-15
Release date:2002-12-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of OxyB, a Cytochrome P450 Implicated in an Oxidative Phenol Coupling Reaction during Vancomycin Biosynthesis.
J.Biol.Chem., 277, 2002
1LFK
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BU of 1lfk by Molmil
Crystal structure of OxyB, a Cytochrome P450 Implicated in an Oxidative Phenol Coupling Reaction During Vancomycin Biosynthesis
Descriptor: P450 monooxygenase, PROTOPORPHYRIN IX CONTAINING FE
Authors:Pylypenko, O, Zerbe, K, Vitali, F, Zhang, W, Vrijbloed, J.W, Robinson, J.A, Schlichting, I.
Deposit date:2002-04-11
Release date:2002-12-11
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structure of OxyB, a Cytochrome P450 Implicated in an Oxidative Phenol Coupling Reaction during Vancomycin Biosynthesis.
J.Biol.Chem., 277, 2002
1UED
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BU of 1ued by Molmil
Crystal Structure of OxyC a Cytochrome P450 Implicated in an Oxidative C-C Coupling Reaction During Vancomycin Biosynthesis.
Descriptor: DI(HYDROXYETHYL)ETHER, P450 monooxygenase, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Pylypenko, O, Vitali, F, Zerbe, K, Robinson, J.A, Schlichting, I.
Deposit date:2003-05-11
Release date:2003-12-09
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of OxyC, a cytochrome P450 implicated in an oxidative C-C coupling reaction during vancomycin biosynthesis
J.Biol.Chem., 278, 2003
2LAQ
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BU of 2laq by Molmil
Solution structure of the Sex Peptide from Drosophila melanogaster
Descriptor: Accessory gland-specific peptide 70A
Authors:Moehle, K, Freund, A, Robinson, J.A.
Deposit date:2011-03-17
Release date:2011-04-27
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:NMR studies of the solution conformation of the sex peptide from Drosophila melanogaster.
Febs Lett., 585, 2011
2NS4
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BU of 2ns4 by Molmil
Solution structure of a Beta-Hairpin Peptidomimetic Inhibitor of the BIV Tat-Tar Interaction
Descriptor: L-22 CYCLIC PEPTIDE
Authors:Moehle, K, Patora, K, Robinson, J.A.
Deposit date:2006-11-03
Release date:2007-01-30
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Structure-Guided Peptidomimetic Design Leads to Nanomolar beta-Hairpin Inhibitors of the Tat-TAR Interaction of Bovine Immunodeficiency Virus
Biochemistry, 46, 2007
7DNG
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BU of 7dng by Molmil
DARPin 63_B7 in complex with linear V3-crown (MN) peptide
Descriptor: DARPin 63_B7, linear V3-crown (MN) peptide
Authors:Wu, Y, Plueckthun, A.
Deposit date:2020-12-09
Release date:2021-12-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Distinct conformations of the HIV-1 V3 loop crown are targetable for broad neutralization.
Nat Commun, 12, 2021
7DNF
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BU of 7dnf by Molmil
DARPin 63_B7 in complex with V3-IY (MN) crown mimetic
Descriptor: DARPin 63_B7, SULFATE ION, V3-IY (MN) crown mimetic peptide
Authors:Wu, Y, Plueckthun, A.
Deposit date:2020-12-09
Release date:2021-12-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Distinct conformations of the HIV-1 V3 loop crown are targetable for broad neutralization.
Nat Commun, 12, 2021
7DNE
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BU of 7dne by Molmil
DARPin 5m3_D12 in complex with V3-IY (MN) crown mimetic
Descriptor: DARPin 5m3_D12, V3-IY (MN) crown mimetic peptide
Authors:Wu, Y, Plueckthun, A.
Deposit date:2020-12-09
Release date:2021-12-22
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Distinct conformations of the HIV-1 V3 loop crown are targetable for broad neutralization.
Nat Commun, 12, 2021
1JRH
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BU of 1jrh by Molmil
COMPLEX (ANTIBODY/ANTIGEN)
Descriptor: ANTIBODY A6, INTERFERON-GAMMA RECEPTOR ALPHA CHAIN
Authors:Winkler, F.K, Sogabe, S.
Deposit date:1997-09-23
Release date:1998-03-25
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Neutralizing epitopes on the extracellular interferon gamma receptor (IFNgammaR) alpha-chain characterized by homolog scanning mutagenesis and X-ray crystal structure of the A6 fab-IFNgammaR1-108 complex.
J.Mol.Biol., 273, 1997
2KX5
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BU of 2kx5 by Molmil
Recognition of HIV TAR RNA by peptide mimetic of Tat protein
Descriptor: Cyclic peptide mimetic of Tat protein, HIV TAR RNA
Authors:Davidson, A, Patora-Komisarska, K, Robinson, J, Varani, G.
Deposit date:2010-04-26
Release date:2010-07-07
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Essential structural requirements for specific recognition of HIV TAR RNA by peptide mimetics of Tat protein.
Nucleic Acids Res., 39, 2011
6GD5
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BU of 6gd5 by Molmil
The solution structure of the LptA-Thanatin complex
Descriptor: Lipopolysaccharide export system protein LptA, Thanatin
Authors:Moehle, K, Zerbe, O.
Deposit date:2018-04-22
Release date:2018-11-28
Last modified:2019-05-08
Method:SOLUTION NMR
Cite:Thanatin targets the intermembrane protein complex required for lipopolysaccharide transport inEscherichia coli.
Sci Adv, 4, 2018
2AXI
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BU of 2axi by Molmil
HDM2 in complex with a beta-hairpin
Descriptor: 3[N-MORPHOLINO]PROPANE SULFONIC ACID, SULFATE ION, Ubiquitin-protein ligase E3 Mdm2, ...
Authors:Mittl, P.R.E, Fasan, R, Robinson, J, Gruetter, M.G.
Deposit date:2005-09-05
Release date:2006-03-21
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structure-Activity Studies in a Family of beta-Hairpin Protein Epitope Mimetic Inhibitors of the p53-HDM2 Protein-Protein Interaction.
Chembiochem, 7, 2006
2FLG
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BU of 2flg by Molmil
Solution structure of an EGF-LIKE domain from the Plasmodium falciparum merozoite surface protein 1
Descriptor: Merozoite surface protein 1
Authors:James, S, Moehle, K, Pluschke, G, Robinson, J.
Deposit date:2006-01-06
Release date:2006-02-21
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Synthesis, solution structure and immune recognition of an epidermal growth factor-like domain from Plasmodium falciparum merozoite surface protein-1.
Chembiochem, 7, 2006
2M7I
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BU of 2m7i by Molmil
Solution structure of a Beta-Hairpin Peptidomimetic antibiotic that targets LptD in Pseudomonas sp.
Descriptor: Beta-Hairpin Peptidomimetic antibiotic TWL(DAB)(ORN)(DLY)RW(ORN)(DAB)AK(DPR)P
Authors:Moehle, K, Schmidt, J, Robinson, J.
Deposit date:2013-04-24
Release date:2013-09-11
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural studies of beta-hairpin peptidomimetic antibiotics that target LptD in Pseudomonas sp.
Bioorg.Med.Chem., 21, 2013
2N8X
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BU of 2n8x by Molmil
Solution structure of LptE from Pseudomonas Aerigunosa
Descriptor: LPS-assembly lipoprotein LptE
Authors:Moehle, K, Kocherla, H, Jurt, S, Robinson, J, Zerbe, O, Zerbe, K, Bacsa, B.
Deposit date:2015-10-28
Release date:2016-05-25
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution Structure and Dynamics of LptE from Pseudomonas aeruginosa.
Biochemistry, 55, 2016
2M7J
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BU of 2m7j by Molmil
Solution Structure of a Beta-Hairpin Peptidomimetic antibiotic that target LptD in Pseudomonas sp.
Descriptor: beta-Hairpin Peptidomimetic Antibiotic TWLKKRRWKKAK(DPR)P
Authors:Moehle, K, Schmidt, J, Robinson, J.
Deposit date:2013-04-25
Release date:2013-09-11
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural studies of beta-hairpin peptidomimetic antibiotics that target LptD in Pseudomonas sp.
Bioorg.Med.Chem., 21, 2013
6D2U
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BU of 6d2u by Molmil
Solution structure of a ultra-high affinity macrocycle bound to HIV-1 TAR RNA
Descriptor: DAB-VAL-ARG-THR-ARG-LYS-GLY-ARG-ARG-ILE-NOR-ILE-DPR-PRO, RNA (29-MER)
Authors:Shortridge, M.D, Varani, G.
Deposit date:2018-04-13
Release date:2018-12-12
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:An ultra-high affinity ligand of HIV-1 TAR reveals the RNA structure recognized by P-TEFb.
Nucleic Acids Res., 47, 2019
2KDQ
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Simultaneous recognition of HIV-1 TAR RNA bulge and loop sequences by cyclic peptide mimic of Tat protein
Descriptor: HIV-1 TAR RNA, L-22 CYCLIC PEPTIDE
Authors:Davidson, A, Leeper, T.C, Varani, G.
Deposit date:2009-01-14
Release date:2009-06-23
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Simultaneous recognition of HIV-1 TAR RNA bulge and loop sequences by cyclic peptide mimics of Tat protein
Proc.Natl.Acad.Sci.USA, 106, 2009

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