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1Z92
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BU of 1z92 by Molmil
structure of interleukin-2 with its alpha receptor
Descriptor: Interleukin-2, Interleukin-2 receptor alpha chain
Authors:Rickert, M, Wang, X.Q, Goriatcheva, N, Boulanger, M.J, Garcia, K.C.
Deposit date:2005-03-31
Release date:2005-06-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The structure of interleukin-2 complexed with its alpha receptor.
Science, 308, 2005
2OZ2
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BU of 2oz2 by Molmil
Crystal structure analysis of cruzain bound to vinyl sulfone derived inhibitor (K11777)
Descriptor: Cruzipain, NALPHA-[(4-METHYLPIPERAZIN-1-YL)CARBONYL]-N-{(1S)-3-PHENYL-1-[2-(PHENYLSULFONYL)ETHYL]PROPYL}-L-PHENYLALANINAMIDE, SULFATE ION
Authors:Rickert, M, Brinen, L.
Deposit date:2007-02-23
Release date:2008-02-26
Last modified:2019-09-04
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Vinyl sulfones as antiparasitic agents and a structural basis for drug design.
J.Biol.Chem., 284, 2009
2B5I
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BU of 2b5i by Molmil
cytokine receptor complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cytokine receptor common gamma chain, ...
Authors:Wang, X, Rickert, M, Garcia, K.C.
Deposit date:2005-09-28
Release date:2005-11-29
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the quaternary complex of interleukin-2 with its alpha, beta, and gammac receptors.
Science, 310, 2005
5EPM
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BU of 5epm by Molmil
Ceratotoxin variant in complex with specific antibody Fab fragment
Descriptor: Antibody Fab fragment heavy chain, Antibody Fab fragment light chain, Beta-theraphotoxin-Cm1a
Authors:Strop, P, Shcherbatko, A, Rossi, A.
Deposit date:2015-11-11
Release date:2016-05-04
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Engineering Highly Potent and Selective Microproteins against Nav1.7 Sodium Channel for Treatment of Pain.
J.Biol.Chem., 291, 2016
3BWK
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BU of 3bwk by Molmil
Crystal Structure of Falcipain-3 with Its inhibitor, K11017
Descriptor: Cysteine protease falcipain-3, N~2~-(morpholin-4-ylcarbonyl)-N-[(3S)-1-phenyl-5-(phenylsulfonyl)pentan-3-yl]-L-leucinamide, SULFATE ION
Authors:Kerr, I, Lee, J.H, Brinen, L.S.
Deposit date:2008-01-09
Release date:2009-01-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Vinyl sulfones as antiparasitic agents and a structural basis for drug design.
J.Biol.Chem., 284, 2009
4GS7
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BU of 4gs7 by Molmil
Structure of the Interleukin-15 quaternary complex
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Ring, A.M, Ozkan, E, Feng, D, Garcia, K.C.
Deposit date:2012-08-27
Release date:2012-11-07
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Mechanistic and structural insight into the functional dichotomy between IL-2 and IL-15.
Nat.Immunol., 13, 2012
4DZ8
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BU of 4dz8 by Molmil
human IgG1 Fc fragment Heterodimer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region
Authors:Strop, P.
Deposit date:2012-02-29
Release date:2012-08-01
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Generating Bispecific Human IgG1 and IgG2 Antibodies from Any Antibody Pair.
J.Mol.Biol., 420, 2012
2P7U
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BU of 2p7u by Molmil
The crystal structure of rhodesain, the major cysteine protease of T. brucei rhodesiense, bound to inhibitor K777
Descriptor: Cysteine protease, NALPHA-[(4-METHYLPIPERAZIN-1-YL)CARBONYL]-N-{(1S)-3-PHENYL-1-[2-(PHENYLSULFONYL)ETHYL]PROPYL}-L-PHENYLALANINAMIDE
Authors:Brinen, L.S, Marion, R.
Deposit date:2007-03-20
Release date:2008-03-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Vinyl sulfones as antiparasitic agents and a structural basis for drug design.
J.Biol.Chem., 284, 2009

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