3ZGC
 
 | | crystal structure of the KEAP1-NEH2 complex | | 分子名称: | ACETATE ION, KELCH-LIKE ECH-ASSOCIATED PROTEIN 1, NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR 2 | | 著者 | Hoerer, S, Reinert, D, Ostmann, K, Hoevels, Y, Nar, H. | | 登録日 | 2012-12-17 | | 公開日 | 2013-06-12 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal-Contact Engineering to Obtain a Crystal Form of the Kelch Domain of Human Keap1 Suitable for Ligand-Soaking Experiments.
Acta Crystallogr.,Sect.F, 69, 2013
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3ZGD
 | | crystal structure of a KEAP1 mutant | | 分子名称: | ACETATE ION, KELCH-LIKE ECH-ASSOCIATED PROTEIN 1, SODIUM ION | | 著者 | Hoerer, S, Reinert, D, Ostmann, K, Hoevels, Y, Nar, H. | | 登録日 | 2012-12-17 | | 公開日 | 2013-06-12 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Crystal-Contact Engineering to Obtain a Crystal Form of the Kelch Domain of Human Keap1 Suitable for Ligand-Soaking Experiments.
Acta Crystallogr.,Sect.F, 69, 2013
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4BB9
 | | Crystal structure of glucokinase regulatory protein complexed to fructose-1-phosphate | | 分子名称: | 1-O-phosphono-beta-D-fructopyranose, CALCIUM ION, GLUCOKINASE REGULATORY PROTEIN | | 著者 | Pautsch, A, Stadler, N, Loehle, A, Lenter, M, Rist, W, Berg, A, Glocker, L, Nar, H, Reinert, D, Heckel, A, Schnapp, G, Kauschke, S.G. | | 登録日 | 2012-09-21 | | 公開日 | 2013-05-15 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | | 主引用文献 | Crystal Structure of Glucokinase Regulatory Protein.
Biochemistry, 52, 2013
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4BBA
 | | Crystal structure of glucokinase regulatory protein complexed to phosphate | | 分子名称: | GLUCOKINASE REGULATORY PROTEIN, PHOSPHATE ION | | 著者 | Pautsch, A, Stadler, N, Loehle, A, Lenter, M, Rist, W, Berg, A, Glocker, L, Nar, H, Reinhart, D, Heckel, A, Schnapp, G, Kauschke, S.G. | | 登録日 | 2012-09-21 | | 公開日 | 2013-05-15 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Crystal Structure of Glucokinase Regulatory Protein.
Biochemistry, 52, 2013
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7ALA
 | | human GCH-GFRP inhibitory complex | | 分子名称: | 2-azanyl-8-[(4-fluorophenyl)methylsulfanyl]-1,7-dihydropurin-6-one, GTP cyclohydrolase 1, GTP cyclohydrolase 1 feedback regulatory protein, ... | | 著者 | Ebenhoch, R, Nar, H. | | 登録日 | 2020-10-06 | | 公開日 | 2021-10-13 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.846 Å) | | 主引用文献 | A hybrid approach reveals the allosteric regulation of GTP cyclohydrolase I.
Proc.Natl.Acad.Sci.USA, 117, 2020
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7ALC
 | | human GCH-GFRP stimulatory complex | | 分子名称: | GTP cyclohydrolase 1, GTP cyclohydrolase 1 feedback regulatory protein, PHENYLALANINE, ... | | 著者 | Ebenhoch, R, Nar, H. | | 登録日 | 2020-10-06 | | 公開日 | 2021-10-13 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.726 Å) | | 主引用文献 | A hybrid approach reveals the allosteric regulation of GTP cyclohydrolase I.
Proc.Natl.Acad.Sci.USA, 117, 2020
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7AL9
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7ALB
 | | human GCH-GFRP stimulatory complex 7-deaza-GTP bound | | 分子名称: | 7-deaza-GTP, GTP cyclohydrolase 1, GTP cyclohydrolase 1 feedback regulatory protein, ... | | 著者 | Ebenhoch, R, Nar, H. | | 登録日 | 2020-10-06 | | 公開日 | 2021-10-13 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.979 Å) | | 主引用文献 | A hybrid approach reveals the allosteric regulation of GTP cyclohydrolase I.
Proc.Natl.Acad.Sci.USA, 117, 2020
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7ALQ
 | | human GCH-GFRP inhibitory complex 7-deaza-GTP bound | | 分子名称: | 7,8-DIHYDROBIOPTERIN, 7-deaza-GTP, GTP cyclohydrolase 1, ... | | 著者 | Ebenhoch, R, Nar, H. | | 登録日 | 2020-10-07 | | 公開日 | 2021-10-20 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.205 Å) | | 主引用文献 | Biophysical and structural investigation of the regulation of human GTP cyclohydrolase I by its regulatory protein GFRP.
J.Struct.Biol., 213, 2021
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6Z86
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6Z88
 | | human GTP cyclohydrolase I in complex with allosteric inhibitor | | 分子名称: | 5-azanyl-[1,3]thiazolo[5,4-d]pyrimidine-2,7-dione, GTP cyclohydrolase 1, ZINC ION | | 著者 | Ebenhoch, R, Nar, H. | | 登録日 | 2020-06-02 | | 公開日 | 2020-12-09 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.687 Å) | | 主引用文献 | A hybrid approach reveals the allosteric regulation of GTP cyclohydrolase I.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6Z89
 | | human GTP cyclohydrolase I in complex with allosteric inhibitor | | 分子名称: | 5-azanyl-[1,3]thiazolo[5,4-d]pyrimidine-2,7-dione, GTP cyclohydrolase 1, ZINC ION | | 著者 | Ebenhoch, R, Nar, H. | | 登録日 | 2020-06-02 | | 公開日 | 2020-12-09 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.366 Å) | | 主引用文献 | A hybrid approach reveals the allosteric regulation of GTP cyclohydrolase I.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6Z87
 | | human GTP cyclohydrolase I | | 分子名称: | GTP cyclohydrolase 1, ZINC ION | | 著者 | Ebenhoch, R, Nar, H. | | 登録日 | 2020-06-02 | | 公開日 | 2020-12-09 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.564 Å) | | 主引用文献 | A hybrid approach reveals the allosteric regulation of GTP cyclohydrolase I.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6Z80
 | | stimulatory human GTP cyclohydrolase I - GFRP complex | | 分子名称: | 8-OXO-GUANOSINE-5'-TRIPHOSPHATE, GTP cyclohydrolase 1, GTP cyclohydrolase 1 feedback regulatory protein, ... | | 著者 | Ebenhoch, R, Nar, H, Vonck, J. | | 登録日 | 2020-06-02 | | 公開日 | 2020-12-09 | | 最終更新日 | 2020-12-23 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | A hybrid approach reveals the allosteric regulation of GTP cyclohydrolase I.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6Z85
 | | inhibitory human GTP cyclohydrolase I - GFRP complex | | 分子名称: | 7,8-DIHYDROBIOPTERIN, GTP cyclohydrolase 1, GTP cyclohydrolase 1 feedback regulatory protein, ... | | 著者 | Ebenhoch, R, Nar, H, Vonck, J. | | 登録日 | 2020-06-02 | | 公開日 | 2020-12-09 | | 最終更新日 | 2020-12-23 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | A hybrid approach reveals the allosteric regulation of GTP cyclohydrolase I.
Proc.Natl.Acad.Sci.USA, 117, 2020
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7ACC
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