2XBB
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![BU of 2xbb by Molmil](/molmil-images/mine/2xbb) | Nedd4 HECT:Ub complex | Descriptor: | E3 UBIQUITIN-PROTEIN LIGASE NEDD4, GLYCEROL, UBIQUITIN | Authors: | Maspero, E, Cecatiello, V, Musacchio, A, Polo, S, Pasqualato, S. | Deposit date: | 2010-04-08 | Release date: | 2011-03-23 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.68 Å) | Cite: | Structure of the Hect:Ubiquitin Complex and its Role in Ubiquitin Chain Elongation Embo Rep., 12, 2011
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2C7N
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![BU of 2c7n by Molmil](/molmil-images/mine/2c7n) | Human Rabex-5 residues 1-74 in complex with Ubiquitin | Descriptor: | RAB GUANINE NUCLEOTIDE EXCHANGE FACTOR 1, UBIQUITIN, ZINC ION | Authors: | Penengo, L, Mapelli, M, Murachelli, A.G, Confalioneri, S, Magri, L, Musacchio, A, Di Fiore, P.P, Polo, S, Schneider, T.R. | Deposit date: | 2005-11-25 | Release date: | 2006-02-15 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structure of the Ubiquitin Binding Domains of Rabex-5 Reveals Two Modes of Interaction with Ubiquitin. Cell(Cambridge,Mass.), 124, 2006
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2C7M
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![BU of 2c7m by Molmil](/molmil-images/mine/2c7m) | Human Rabex-5 residues 1-74 in complex with Ubiquitin | Descriptor: | RAB GUANINE NUCLEOTIDE EXCHANGE FACTOR 1, UBIQUITIN, ZINC ION | Authors: | Penengo, L, Mapelli, M, Murachelli, A.G, Confalioneri, S, Magri, L, Musacchio, A, Di Fiore, P.P, Polo, S, Schneider, T.R. | Deposit date: | 2005-11-25 | Release date: | 2006-02-15 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of the ubiquitin binding domains of rabex-5 reveals two modes of interaction with ubiquitin. Cell, 124, 2006
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4BBN
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![BU of 4bbn by Molmil](/molmil-images/mine/4bbn) | NEDD4 HECT-Ub:Ub complex | Descriptor: | E3 UBIQUITIN-PROTEIN LIGASE NEDD4, POLYUBIQUITIN-B | Authors: | Maspero, E, Valentini, E, Mari, S, Cecatiello, V, Polo, S, Pasqualato, S. | Deposit date: | 2012-09-27 | Release date: | 2013-05-01 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Structure of a Ubiquitin-Loaded Hect Ligase Reveals the Molecular Basis for Catalytic Priming Nat.Struct.Mol.Biol., 20, 2013
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4BE8
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![BU of 4be8 by Molmil](/molmil-images/mine/4be8) | NEDD4 HECT A889F structure | Descriptor: | E3 UBIQUITIN-PROTEIN LIGASE NEDD4 | Authors: | Maspero, E, Valentini, E, Mari, S, Cecatiello, V, Polo, S, Pasqualato, S. | Deposit date: | 2013-03-06 | Release date: | 2013-05-01 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.996 Å) | Cite: | Structure of a Ubiquitin-Loaded Hect Ligase Reveals the Molecular Basis for Catalytic Priming Nat.Struct.Mol.Biol., 20, 2013
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2XBF
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![BU of 2xbf by Molmil](/molmil-images/mine/2xbf) | Nedd4 HECT structure | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, E3 UBIQUITIN-PROTEIN LIGASE NEDD4 | Authors: | Maspero, E, Cecatiello, V, Musacchio, A, Polo, S, Pasqualato, S. | Deposit date: | 2010-04-09 | Release date: | 2011-03-23 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.503 Å) | Cite: | Structure of the Hect:Ubiquitin Complex and its Role in Ubiquitin Chain Elongation Embo Rep., 12, 2011
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2AGA
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![BU of 2aga by Molmil](/molmil-images/mine/2aga) | De-ubiquitinating function of ataxin-3: insights from the solution structure of the Josephin domain | Descriptor: | Machado-Joseph disease protein 1 | Authors: | Mao, Y, Senic-Matuglia, F, Di Fiore, P, Polo, S, Hodsdon, M.E, De Camilli, P. | Deposit date: | 2005-07-26 | Release date: | 2005-08-30 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | Deubiquitinating function of ataxin-3: insights from the solution structure of the Josephin domain. Proc.Natl.Acad.Sci.Usa, 102, 2005
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2N5M
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![BU of 2n5m by Molmil](/molmil-images/mine/2n5m) | Unveiling the structural determinants of KIAA0323 binding preference for NEDD8 | Descriptor: | Protein KHNYN | Authors: | Santonico, E, Nepravishta, R, Mattioni, A, Valentini, E, Mandaliti, W, Procopio, R, Iannuccelli, M, Castagnoli, L, Polo, S, Paci, M, Cesareni, G. | Deposit date: | 2015-07-21 | Release date: | 2016-07-27 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Unveiling the structural determinants of KIAA0323 binding preference for NEDD8. To be Published
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2N7K
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![BU of 2n7k by Molmil](/molmil-images/mine/2n7k) | Unveiling the structural determinants of KIAA0323 binding preference for NEDD8 | Descriptor: | NEDD8, Protein KHNYN | Authors: | Santonico, E, Nepravishta, R, Mattioni, A, Valentini, E, Mandaliti, W, Procopio, R, Iannuccelli, M, Castagnoli, L, Polo, S, Paci, M, Cesareni, G. | Deposit date: | 2015-09-14 | Release date: | 2016-09-14 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Unveiling the structural determinants of KIAA0323 binding preference for NEDD8 To be Published
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6FYH
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![BU of 6fyh by Molmil](/molmil-images/mine/6fyh) | Disulfide between ubiquitin G76C and the E3 HECT ligase Huwe1 | Descriptor: | E3 ubiquitin-protein ligase HUWE1, Polyubiquitin-B, SULFATE ION, ... | Authors: | Jaeckl, M, Hartmann, M.D, Wiesner, S. | Deposit date: | 2018-03-12 | Release date: | 2018-07-11 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.906 Å) | Cite: | beta-Sheet Augmentation Is a Conserved Mechanism of Priming HECT E3 Ligases for Ubiquitin Ligation. J. Mol. Biol., 430, 2018
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6FX4
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![BU of 6fx4 by Molmil](/molmil-images/mine/6fx4) | |
6E5N
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![BU of 6e5n by Molmil](/molmil-images/mine/6e5n) | |
2N11
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![BU of 2n11 by Molmil](/molmil-images/mine/2n11) | |
2N13
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![BU of 2n13 by Molmil](/molmil-images/mine/2n13) | |
2N0Z
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![BU of 2n0z by Molmil](/molmil-images/mine/2n0z) | |
2N10
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![BU of 2n10 by Molmil](/molmil-images/mine/2n10) | |
2N12
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![BU of 2n12 by Molmil](/molmil-images/mine/2n12) | |
1HTL
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![BU of 1htl by Molmil](/molmil-images/mine/1htl) | |
1LT4
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![BU of 1lt4 by Molmil](/molmil-images/mine/1lt4) | HEAT-LABILE ENTEROTOXIN MUTANT S63K | Descriptor: | HEAT-LABILE ENTEROTOXIN, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | Authors: | Van Den Akker, F, Hol, W.G.J. | Deposit date: | 1997-04-14 | Release date: | 1997-06-16 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of a non-toxic mutant of heat-labile enterotoxin, which is a potent mucosal adjuvant. Protein Sci., 6, 1997
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1LTG
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![BU of 1ltg by Molmil](/molmil-images/mine/1ltg) | |