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2N12

Solution structure of human Myosin VI isoform3 (1050-1131)

Summary for 2N12
Entry DOI10.2210/pdb2n12/pdb
Related2N0Z 2N10 2N11 2N13 6E5N
NMR InformationBMRB: 25544
DescriptorUnconventional myosin-VI (1 entity in total)
Functional Keywordsmotor protein, protein transport
Biological sourceHomo sapiens (Human)
Cellular locationGolgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Isoform 3: Cytoplasmic vesicle, clathrin- coated vesicle membrane. Isoform 4: Cytoplasmic vesicle, clathrin- coated vesicle membrane: Q9UM54
Total number of polymer chains1
Total formula weight9580.19
Authors
He, F.,Walters, K. (deposition date: 2015-03-20, release date: 2016-03-02, Last modification date: 2021-11-03)
Primary citationWollscheid, H.P.,Biancospino, M.,He, F.,Magistrati, E.,Molteni, E.,Lupia, M.,Soffientini, P.,Rottner, K.,Cavallaro, U.,Pozzoli, U.,Mapelli, M.,Walters, K.J.,Polo, S.
Diverse functions of myosin VI elucidated by an isoform-specific alpha-helix domain.
Nat.Struct.Mol.Biol., 23:300-308, 2016
Cited by
PubMed: 26950368
DOI: 10.1038/nsmb.3187
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

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