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3KGS
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BU of 3kgs by Molmil
V30M mutant human transthyretin (TTR) (apoV30M) pH 7.5
分子名称: Transthyretin
著者Trivella, D.B, Polikarpov, I.
登録日2009-10-29
公開日2010-03-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Conformational differences between the wild type and V30M mutant transthyretin modulate its binding to genistein: implications to tetramer stability and ligand-binding.
J.Struct.Biol., 170, 2010
3KGT
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BU of 3kgt by Molmil
V30M mutant human transthyretin (TTR) complexed with genistein (V30M:GEN) pH 7.5
分子名称: GENISTEIN, Transthyretin
著者Trivella, D.B, Polikarpov, I.
登録日2009-10-29
公開日2010-03-23
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Conformational differences between the wild type and V30M mutant transthyretin modulate its binding to genistein: implications to tetramer stability and ligand-binding.
J.Struct.Biol., 170, 2010
3C9X
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BU of 3c9x by Molmil
Crystal structure of Trichoderma reesei aspartic proteinase
分子名称: GLYCEROL, Trichoderma reesei Aspartic protease
著者Nascimento, A.S, Krauchenco, S, Golubev, A.M, Gustchina, A, Wlodawer, A, Polikarpov, I.
登録日2008-02-19
公開日2008-08-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Statistical coupling analysis of aspartic proteinases based on crystal structures of the Trichoderma reesei enzyme and its complex with pepstatin A.
J.Mol.Biol., 382, 2008
3CFT
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BU of 3cft by Molmil
Crystal structure of human transthyretin in complex with 1-amino-5-naphthalene sulfonate
分子名称: 5-aminonaphthalene-1-sulfonic acid, Transthyretin
著者Lima, L.-M.T.R, Foguel, D, Polikarpov, I.
登録日2008-03-04
公開日2009-03-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Identification of a novel ligand binding motif in the transthyretin channel.
Bioorg.Med.Chem., 18, 2010
3DLQ
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BU of 3dlq by Molmil
Crystal structure of the IL-22/IL-22R1 complex
分子名称: Interleukin-22, Interleukin-22 receptor subunit alpha-1
著者Bleicher, L, de Moura, P.R, Watanabe, L, Colau, D, Dumoutier, L, Renauld, J.-C, Polikarpov, I.
登録日2008-06-28
公開日2008-08-19
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the IL-22/IL-22R1 complex and its implications for the IL-22 signaling mechanism
Febs Lett., 582, 2008
3CFQ
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BU of 3cfq by Molmil
Crystal structure of human wild-type transthyretin in complex with diclofenac
分子名称: 2-[2,6-DICHLOROPHENYL)AMINO]BENZENEACETIC ACID, Transthyretin
著者Lima, L.-M.T.R, Foguel, D, Polikarpov, I.
登録日2008-03-04
公開日2009-03-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Identification of a novel ligand binding motif in the transthyretin channel.
Bioorg.Med.Chem., 18, 2010
3CFN
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BU of 3cfn by Molmil
Crystal structure of human transthyretin in complex with 1-anilino-8-naphthalene sulfonate
分子名称: 8-ANILINO-1-NAPHTHALENE SULFONATE, Transthyretin
著者Lima, L.-M.T.R, Foguel, D, Polikarpov, I.
登録日2008-03-04
公開日2009-03-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Identification of a novel ligand binding motif in the transthyretin channel.
Bioorg.Med.Chem., 18, 2010
3CFM
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BU of 3cfm by Molmil
Crystal structure of the apo form of human wild-type transthyretin
分子名称: Transthyretin
著者Lima, L.-M.T.R, Foguel, D, Polikarpov, I.
登録日2008-03-04
公開日2009-03-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Identification of a novel ligand binding motif in the transthyretin channel.
Bioorg.Med.Chem., 18, 2010
3EMY
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BU of 3emy by Molmil
Crystal structure of Trichoderma reesei aspartic proteinase complexed with pepstatin A
分子名称: Pepstatin, Trichoderma reesei Aspartic protease
著者Nascimento, A.S, Krauchenco, S, Golubev, A.M, Gustchina, A, Wlodawer, A, Polikarpov, I.
登録日2008-09-25
公開日2008-10-07
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Statistical coupling analysis of aspartic proteinases based on crystal structures of the Trichoderma reesei enzyme and its complex with pepstatin A.
J.Mol.Biol., 382, 2008
3EXD
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BU of 3exd by Molmil
Sulfur-SAD phased HEWL Crystal
分子名称: Lysozyme C
著者Nascimento, A.S, Liberato, M.V, Polikarpov, I.
登録日2008-10-16
公開日2008-10-28
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献The MX2 macromolecular crystallography beamline: a wiggler X-ray source at the LNLS.
J.Synchrotron Radiat., 16, 2009
4BCR
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BU of 4bcr by Molmil
Structure of PPARalpha in complex with WY14643
分子名称: 1,2-ETHANEDIOL, 2-({4-CHLORO-6-[(2,3-DIMETHYLPHENYL)AMINO]PYRIMIDIN-2-YL}SULFANYL)ACETIC ACID, PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA
著者Bernardes, A, Muniz, J.R.C, Polikarpov, I.
登録日2012-10-02
公開日2013-05-29
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.497 Å)
主引用文献Molecular Mechanism of Peroxisome Proliferator-Activated Receptor Alpha Activation by Wy14643: A New Mode of Ligand Recognition and Receptor Stabilization
J.Mol.Biol., 425, 2013
4DEU
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BU of 4deu by Molmil
Crystal Structure of the Wild Type TTR Binding Naringenin (TTRwt:NAR)
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, NARINGENIN, ...
著者Trivella, D.B.B, Polikarpov, I.
登録日2012-01-22
公開日2012-11-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.599 Å)
主引用文献Flavonoid interactions with human transthyretin: Combined structural and thermodynamic analysis.
J.Struct.Biol., 180, 2012
4CI4
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BU of 4ci4 by Molmil
Structural basis for GL479 a dual Peroxisome Proliferator-Activated Receptor alpha agonist
分子名称: 2-methyl-2-[4-[2-[4-[(E)-phenyldiazenyl]phenoxy]ethyl]phenoxy]propanoic acid, PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA
著者Santos, J.C, Bernardes, A, Polikarpov, I.
登録日2013-12-05
公開日2014-12-24
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.302 Å)
主引用文献Different binding and recognition modes of GL479, a dual agonist of Peroxisome Proliferator-Activated Receptor alpha / gamma.
J. Struct. Biol., 191, 2015
4DES
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BU of 4des by Molmil
Crystal Structure of the Wild Type TTR Binding Chrysin (TTRwt:CHR)
分子名称: Transthyretin, chrysin
著者Trivella, D.B.B, Polikarpov, I.
登録日2012-01-21
公開日2012-11-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Flavonoid interactions with human transthyretin: Combined structural and thermodynamic analysis.
J.Struct.Biol., 180, 2012
4CI5
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BU of 4ci5 by Molmil
Structural basis for GL479 a dual Peroxisome Proliferator-Activated Receptor gamma agonist
分子名称: 2-methyl-2-[4-[2-[4-[(E)-phenyldiazenyl]phenoxy]ethyl]phenoxy]propanoic acid, PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA
著者Santos, J.C, Bernardes, A, Polikarpov, I.
登録日2013-12-05
公開日2014-12-24
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Different binding and recognition modes of GL479, a dual agonist of Peroxisome Proliferator-Activated Receptor alpha / gamma.
J. Struct. Biol., 191, 2015
4CVU
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BU of 4cvu by Molmil
Structure of Fungal beta-mannosidase from Glycoside Hydrolase Family 2 of Trichoderma harzianum
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, BETA-MANNOSIDASE, CADMIUM ION, ...
著者Muniz, J.R.C, Aparicio, R, Santos, J.C, Nascimento, A.S, Golubev, A.M, Polikarpov, I.
登録日2014-03-31
公開日2014-07-09
最終更新日2023-07-05
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Insights into the structure and function of fungal beta-mannosidases from glycoside hydrolase family 2 based on multiple crystal structures of the Trichoderma harzianum enzyme.
FEBS J., 281, 2014
4DET
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BU of 4det by Molmil
Crystal Structure of the Wild Type TTR Binding Kaempferol (TTRwt:KAE)
分子名称: 3,5,7-TRIHYDROXY-2-(4-HYDROXYPHENYL)-4H-CHROMEN-4-ONE, Transthyretin
著者Trivella, D.B.B, Polikarpov, I.
登録日2012-01-22
公開日2012-11-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Flavonoid interactions with human transthyretin: Combined structural and thermodynamic analysis.
J.Struct.Biol., 180, 2012
4DEW
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BU of 4dew by Molmil
Crystal Structure of the Wild Type TTR Binding Luteolin (TTRwt:LUT)
分子名称: 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one, Transthyretin
著者Trivella, D.B.B, Polikarpov, I.
登録日2012-01-22
公開日2012-11-21
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.899 Å)
主引用文献Flavonoid interactions with human transthyretin: Combined structural and thermodynamic analysis.
J.Struct.Biol., 180, 2012
4DER
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BU of 4der by Molmil
Crystal Structure of the Wild Type TTR Binding Apigenin (TTRwt:API)
分子名称: 5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one, GLYCEROL, Transthyretin
著者Trivella, D.B.B, Polikarpov, I.
登録日2012-01-21
公開日2012-11-21
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Flavonoid interactions with human transthyretin: Combined structural and thermodynamic analysis.
J.Struct.Biol., 180, 2012
4EMA
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BU of 4ema by Molmil
Human peroxisome proliferator-activated receptor gamma in complex with rosiglitazone
分子名称: 2,4-THIAZOLIDIINEDIONE, 5-[[4-[2-(METHYL-2-PYRIDINYLAMINO)ETHOXY]PHENYL]METHYL]-(9CL), Peroxisome proliferator-activated receptor gamma
著者Liberato, M.V, Nascimento, A.S, Polikarpov, I.
登録日2012-04-11
公開日2013-03-06
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.545 Å)
主引用文献Medium chain fatty acids are selective peroxisome proliferator activated receptor (PPAR) Gamma activators and pan-PPAR partial agonists
Plos One, 7, 2012
1QFE
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BU of 1qfe by Molmil
THE STRUCTURE OF TYPE I 3-DEHYDROQUINATE DEHYDRATASE FROM SALMONELLA TYPHI
分子名称: 3-AMINO-4,5-DIHYDROXY-CYCLOHEX-1-ENECARBOXYLATE, PROTEIN (3-DEHYDROQUINATE DEHYDRATASE)
著者Shrive, A.K, Polikarpov, I, Sawyer, L, Coggins, J.R, Hawkins, A.R.
登録日1999-04-05
公開日2000-04-05
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The two types of 3-dehydroquinase have distinct structures but catalyze the same overall reaction.
Nat.Struct.Biol., 6, 1999
1QG5
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BU of 1qg5 by Molmil
HIGH RESOLUTION CRYSTAL STRUCTURE OF THE BOVINE BETA-LACTOGLOBULIN (ISOFORM A)
分子名称: BETA-LACTOGLOBULIN
著者Oliveira, K.M.G, Sawyer, L, Polikarpov, I.
登録日1999-04-20
公開日2001-04-21
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of bovine beta-lactoglobulin in the orthorhombic space group C222(1). Structural differences between genetic variants A and B and features of the Tanford transition.
Eur.J.Biochem., 268, 2001
1QLL
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Piratoxin-II (Prtx-II) - a K49 PLA2 from Bothrops pirajai
分子名称: N-TRIDECANOIC ACID, PHOSPHOLIPASE A2
著者Lee, W.-H, Polikarpov, I.
登録日1999-09-01
公開日2000-09-07
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Structural Basis for Low Catalytic Activity in Lys49 Phospholipases A2-A Hypothesis: The Crystal Structure of Piratoxin II Complexed to Fatty Acid
Biochemistry, 40, 2001
1SZN
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BU of 1szn by Molmil
THE STRUCTURE OF ALPHA-GALACTOSIDASE
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Golubev, A.M, Nagem, R.A.P, Brando Neto, J.R, Neustroev, K.N, Eneyskaya, E.V, Kulminskaya, A.A, Shabalin, K.A, Savel'ev, A.N, Polikarpov, I.
登録日2004-04-06
公開日2004-08-10
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献Crystal structure of alpha-galactosidase from Trichoderma reesei and its complex with galactose: implications for catalytic mechanism.
J.Mol.Biol., 339, 2004
1T0O
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BU of 1t0o by Molmil
The structure of alpha-galactosidase from Trichoderma reesei complexed with beta-D-galactose
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Golubev, A.M, Nagem, R.A.P, Brandao Neto, J.R, Neustroev, K.N, Eneyskaya, E.V, Kulminskaya, A.A, Shabalin, K.A, Savel'ev, A.N, Polikarpov, I.
登録日2004-04-12
公開日2004-10-12
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Crystal structure of alpha-galactosidase from Trichoderma reesei and its complex with galactose: implications for catalytic mechanism
J.Mol.Biol., 339, 2004

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