1T0O

The structure of alpha-galactosidase from Trichoderma reesei complexed with beta-D-galactose

Summary for 1T0O

• Entry DOI: 10.2210/pdb1t0o/pdb
• Related: 1SZN
• Descriptor: alpha-galactosidase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• Functional Keywords: (beta/alpha)8 barrel, two domains, glycoprotein, complex, beta-d-galactose, hydrolase
• Biological source: Hypocrea jecorina
• Total number of polymer chains: 1
• Total formula weight: 48623.61

Authors

Golubev, A.M.,Nagem, R.A.P.,Brandao Neto, J.R.,Neustroev, K.N.,Eneyskaya, E.V.,Kulminskaya, A.A.,Shabalin, K.A.,Savel'ev, A.N.,Polikarpov, I. (deposition date: 2004-04-12, release date: 2004-10-12, Last modification date: 2023-08-23)

• Primary citation: Golubev, A.M.,Nagem, R.A.P.,Brandao Neto, J.R.,Neustroev, K.N.,Eneyskaya, E.V.,Kulminskaya, A.A.,Shabalin, K.A.,Savel'ev, A.N.,Polikarpov, I.; Crystal structure of alpha-galactosidase from Trichoderma reesei and its complex with galactose: implications for catalytic mechanism; J.Mol.Biol., 339:413-422, 2004; PubMed: 15136043; DOI: 10.1016/j.jmb.2004.03.062

Experimental method

X-RAY DIFFRACTION (1.96 Å)