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3CDG
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BU of 3cdg by Molmil
Human CD94/NKG2A in complex with HLA-E
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, alpha chain E, ...
Authors:Petrie, E.J, Clements, C.S, Lin, J, Sullivan, L.C, Johnson, D, Huyton, T, Heroux, A, Hoare, H.L, Beddoe, T, Reid, H.H, Wilce, M.C.J, Brooks, A.G, Rossjohn, J.
Deposit date:2008-02-26
Release date:2008-04-22
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:CD94-NKG2A recognition of human leukocyte antigen (HLA)-E bound to an HLA class I leader sequence
J.Exp.Med., 205, 2008
2M96
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BU of 2m96 by Molmil
Solution NMR structure of the RXFP2 LDLa module
Descriptor: CALCIUM ION, Relaxin receptor 2
Authors:Petrie, E.J, Gooley, P.R, Bathgate, A.D.
Deposit date:2013-06-03
Release date:2014-06-04
Method:SOLUTION NMR
Cite:Solution NMR structure of the RXFP2 LDLa module
To be Published
6UX8
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BU of 6ux8 by Molmil
Structure of monobody 33 MLKL N-terminal domain complex
Descriptor: Mixed lineage kinase domain-like protein, Monobody, ZINC ION
Authors:Birkinshaw, R.W, Petrie, E.J, Murphy, J.M.
Deposit date:2019-11-07
Release date:2020-04-01
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Identification of MLKL membrane translocation as a checkpoint in necroptotic cell death using Monobodies.
Proc.Natl.Acad.Sci.USA, 117, 2020
2M7P
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BU of 2m7p by Molmil
RXFP1 utilises hydrophobic moieties on a signalling surface of the LDLa module to mediate receptor activation
Descriptor: CALCIUM ION, Low-density lipoprotein receptor, Relaxin receptor 1
Authors:Kong, R.CK, Petrie, E.J, Mohanty, B, Ling, J, Lee, J.C.Y, Gooley, P.R, Bathgate, R.A.D.
Deposit date:2013-04-29
Release date:2013-08-14
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:The relaxin receptor (RXFP1) utilizes hydrophobic moieties on a signaling surface of its N-terminal low density lipoprotein class A module to mediate receptor activation.
J.Biol.Chem., 288, 2013
6BWK
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BU of 6bwk by Molmil
Crystal structure of the human MLKL pseudokinase domain T357E/S358E mutant
Descriptor: GLYCEROL, Mixed lineage kinase domain-like protein
Authors:Cowan, A.D, Czabotar, P.E, Murphy, J.M.
Deposit date:2017-12-15
Release date:2018-06-27
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosis.
Nat Commun, 9, 2018
4YEF
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BU of 4yef by Molmil
beta1 carbohydrate binding module (CBM) of AMP-activated protein kinase (AMPK) in complex with glucosyl-beta-cyclododextrin
Descriptor: 5'-AMP-activated protein kinase subunit beta-1, Cycloheptakis-(1-4)-(alpha-D-glucopyranose), GLYCEROL, ...
Authors:Mobbs, J, Gorman, M.A, Parker, M.W, Gooley, P.R, Griffin, M.
Deposit date:2015-02-24
Release date:2015-06-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Determinants of oligosaccharide specificity of the carbohydrate-binding modules of AMP-activated protein kinase.
Biochem.J., 468, 2015
4YEE
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BU of 4yee by Molmil
beta2 carbohydrate binding module (CBM) of AMP-activated protein kinase (AMPK) in complex with glucosyl-beta-cyclodextrin
Descriptor: 5'-AMP-activated protein kinase subunit beta-2, Cyclic alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-[alpha-D-glucopyranose-(1-6)]alpha-D-glucopyranose, GLYCEROL
Authors:Mobbs, J, Gorman, M.A, Parker, M.W, Gooley, P.R, Griffin, M.
Deposit date:2015-02-24
Release date:2015-04-01
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Determinants of oligosaccharide specificity of the carbohydrate-binding modules of AMP-activated protein kinase.
Biochem.J., 468, 2015
4Y0G
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BU of 4y0g by Molmil
beta2 carbohydrate binding module (CBM) of AMP-activated protein kinase (AMPK)
Descriptor: 5'-AMP-activated protein kinase subunit beta-2, GLYCEROL
Authors:Mobbs, J, Gorman, M.A, Parker, M.W, Gooley, P.R, Griffin, M.
Deposit date:2015-02-06
Release date:2015-04-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Determinants of oligosaccharide specificity of the carbohydrate-binding modules of AMP-activated protein kinase.
Biochem.J., 468, 2015
6VBZ
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BU of 6vbz by Molmil
Crystal structure of the rat MLKL pseudokinase domain
Descriptor: MANGANESE (II) ION, Mixed lineage kinase domain-like pseudokinase
Authors:Davies, K.A, Czabotar, P.E.
Deposit date:2019-12-19
Release date:2020-07-08
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.192 Å)
Cite:Distinct pseudokinase domain conformations underlie divergent activation mechanisms among vertebrate MLKL orthologues.
Nat Commun, 11, 2020
6VC0
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BU of 6vc0 by Molmil
Crystal structure of the horse MLKL pseudokinase domain
Descriptor: GLYCEROL, Mixed lineage kinase domain like pseudokinase
Authors:Davies, K.A, Czabotar, P.E.
Deposit date:2019-12-19
Release date:2020-07-08
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.746 Å)
Cite:Distinct pseudokinase domain conformations underlie divergent activation mechanisms among vertebrate MLKL orthologues.
Nat Commun, 11, 2020
7JW7
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BU of 7jw7 by Molmil
Structure of monobody 27 human MLKL pseudokinase domain complex
Descriptor: Mixed lineage kinase domain-like protein, Monobody 27
Authors:Meng, Y, Garnish, S.E, Koide, A, Koide, S, Czabotar, P.E, Murphy, J.M.
Deposit date:2020-08-25
Release date:2021-03-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.63 Å)
Cite:Conformational interconversion of MLKL and disengagement from RIPK3 precede cell death by necroptosis.
Nat Commun, 12, 2021
7JXU
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BU of 7jxu by Molmil
Structure of monobody 32 human MLKL pseudokinase domain complex
Descriptor: 1,2-ETHANEDIOL, Mixed lineage kinase domain-like protein, Monobody 32
Authors:Meng, Y, Garnish, S.E, Koide, A, Koide, S, Czabotar, P.E, Murphy, J.M.
Deposit date:2020-08-28
Release date:2021-03-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Conformational interconversion of MLKL and disengagement from RIPK3 precede cell death by necroptosis.
Nat Commun, 12, 2021

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