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3L21
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BU of 3l21 by Molmil
The crystal structure of a dimeric mutant of dihydrodipicolinate synthase (DAPA, RV2753C) from Mycobacterium Tuberculosis - DHDPS-A204R
Descriptor: ACETATE ION, BETA-MERCAPTOETHANOL, CHLORIDE ION, ...
Authors:Evans, G.L, Schuldt, L, Jamerson, G.B, Devenish, S.R, Weiss, M.S, Gerrard, J.A.
Deposit date:2009-12-14
Release date:2010-12-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A dimeric mutant of DHDPS from Mycobacterium tuberculosis
To be Published
4NQ1
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BU of 4nq1 by Molmil
Legionella pneumophila dihydrodipicolinate synthase with first substrate pyruvate bound in the active site
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 4-hydroxy-tetrahydrodipicolinate synthase, ...
Authors:Siddiqui, T, Paxman, J.J.
Deposit date:2013-11-23
Release date:2014-01-01
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Legionella pneumophila DHDPS: The First Case of Non-Lysine Inhibition in a Gram-Negative Pathogen
To be Published
6DCN
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BU of 6dcn by Molmil
Bcl-xL complex with Beclin 1 BH3 domain T108pThr
Descriptor: BCL-xl protein, Beclin-1
Authors:Lee, E.F, Smith, B.J, Smith, N.A, Yao, S, Fairlie, W.D.
Deposit date:2018-05-07
Release date:2018-05-23
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.444 Å)
Cite:Structural insights into BCL2 pro-survival protein interactions with the key autophagy regulator BECN1 following phosphorylation by STK4/MST1.
Autophagy, 15, 2019
3VFL
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BU of 3vfl by Molmil
Structure, Function, Stability and Knockout Phenotype of Dihydrodipicolinate Synthase from Streptococcus pneumoniae
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Dihydrodipicolinate synthase, GLYCEROL, ...
Authors:Gorman, M.A.
Deposit date:2012-01-10
Release date:2013-06-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Structure, Function, Stability and Knockout Phenotype of Dihydrodipicolinate Synthase from Streptococcus pneumoniae
To be Published
4KH3
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BU of 4kh3 by Molmil
Structure of a bacterial self-associating protein
Descriptor: Antigen 43, MALONATE ION
Authors:Heras, B, Gee, C.L, Schembri, M.A, Totsika, M.
Deposit date:2013-04-30
Release date:2014-01-15
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The antigen 43 structure reveals a molecular Velcro-like mechanism of autotransporter-mediated bacterial clumping.
Proc.Natl.Acad.Sci.USA, 111, 2014
5KTL
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BU of 5ktl by Molmil
Dihydrodipicolinate synthase from the industrial and evolutionarily important cyanobacteria Anabaena variabilis.
Descriptor: 4-hydroxy-tetrahydrodipicolinate synthase, MANGANESE (II) ION
Authors:Christensen, J.B, Panjikar, S, Perugini, M.
Deposit date:2016-07-11
Release date:2016-11-30
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structure and Function of Cyanobacterial DHDPS and DHDPR.
Sci Rep, 6, 2016
3HA4
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BU of 3ha4 by Molmil
Crystal structure of the type one membrane protein MIX1 from Leishmania
Descriptor: CARBONATE ION, MIX1
Authors:Gorman, M.A, Walsh, P.J, Parker, M.W.
Deposit date:2009-05-01
Release date:2010-05-05
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of the Leishmania major MIX protein: A scaffold protein that mediates protein-protein interactions.
Protein Sci., 20, 2011
6N44
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BU of 6n44 by Molmil
Sheep Galectin-11 (LGALS11) complex with glycerol
Descriptor: GLYCEROL, Galectin
Authors:Beddoe, T.C, Sakthivel, D.
Deposit date:2018-11-17
Release date:2020-05-20
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:The oligomeric assembly of galectin-11 is critical for anti-parasitic activity in sheep (Ovis aries).
Commun Biol, 3, 2020
6DCO
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BU of 6dco by Molmil
Bcl-xL complex with Beclin 1 BH3 domain T108D
Descriptor: Bcl-2-like protein 1,Bcl-2-like protein 1, Beclin-1, CHLORIDE ION
Authors:Lee, E.F, Smith, B.J, Smith, N.A, Yao, S, Fairlie, W.D.
Deposit date:2018-05-07
Release date:2018-05-30
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.198 Å)
Cite:Structural insights into BCL2 pro-survival protein interactions with the key autophagy regulator BECN1 following phosphorylation by STK4/MST1.
Autophagy, 15, 2019
5WPA
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BU of 5wpa by Molmil
Structure of human SFPQ/PSPC1 heterodimer
Descriptor: Paraspeckle component 1, Splicing factor, proline- and glutamine-rich
Authors:Lee, M.
Deposit date:2017-08-04
Release date:2018-03-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Crystal structure of a SFPQ/PSPC1 heterodimer provides insights into preferential heterodimerization of human DBHS family proteins.
J. Biol. Chem., 293, 2018
3OF6
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BU of 3of6 by Molmil
Human pre-T cell receptor crystal structure
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Pre T-cell antigen receptor alpha, T cell receptor beta chain
Authors:Pang, S.S.
Deposit date:2010-08-13
Release date:2010-10-20
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The structural basis for autonomous dimerization of the pre-T-cell antigen receptor
Nature, 467, 2010
7MDS
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BU of 7mds by Molmil
Crystal structure of AtDHDPS1 in complex with MBDTA-2
Descriptor: 4-hydroxy-tetrahydrodipicolinate synthase 1, chloroplastic, CHLORIDE ION, ...
Authors:Hall, C.J, Soares da Costa, T.P, Panjikar, S.
Deposit date:2021-04-06
Release date:2021-08-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.295 Å)
Cite:Towards novel herbicide modes of action by inhibiting lysine biosynthesis in plants.
Elife, 10, 2021
5AEA
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BU of 5aea by Molmil
Crystal structure of human NCAM domain 1
Descriptor: CITRATE ANION, NEURAL CELL ADHESION MOLECULE 1
Authors:Kvansakul, M, Griffiths, K, Foley, M.
Deposit date:2015-08-27
Release date:2016-04-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:I-Bodies, Human Single Domain Antibodies that Antagonize Chemokine Receptor Cxcr4.
J.Biol.Chem., 291, 2016
4AB0
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BU of 4ab0 by Molmil
X-ray crystal structure of Nicotiana alata defensin NaD1
Descriptor: FLOWER-SPECIFIC DEFENSIN, PHOSPHATE ION
Authors:Mills, G.D, Lay, F.T, Hulett, M.D, Kvansakul, M.
Deposit date:2011-12-06
Release date:2012-04-25
Last modified:2012-06-20
Method:X-RAY DIFFRACTION (1.636 Å)
Cite:Dimerization of Plant Defensin Nad1 Enhances its Antifungal Activity.
J.Biol.Chem., 287, 2012
4AAZ
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BU of 4aaz by Molmil
X-ray structure of Nicotiana alata Defensin 1 NaD1
Descriptor: 1,2-ETHANEDIOL, FLOWER-SPECIFIC DEFENSIN, PHOSPHATE ION
Authors:Lay, F.T, Mills, G.D, Hulett, M.D, Kvansakul, M.
Deposit date:2011-12-06
Release date:2012-04-25
Last modified:2012-08-08
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Dimerization of Plant Defensin Nad1 Enhances its Antifungal Activity.
J.Biol.Chem., 287, 2012
6VVI
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BU of 6vvi by Molmil
Arabidopsis thaliana dihydrodipicolinate synthase isoform 1 (DHDPS1)
Descriptor: 4-hydroxy-tetrahydrodipicolinate synthase 1, chloroplastic, GLYCEROL, ...
Authors:Lee, M, Hall, C.J.
Deposit date:2020-02-18
Release date:2021-02-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.145 Å)
Cite:Differential lysine-mediated allosteric regulation of plant dihydrodipicolinate synthase isoforms.
Febs J., 288, 2021
1YZW
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BU of 1yzw by Molmil
The 2.1A Crystal Structure of the Far-red Fluorescent Protein HcRed: Inherent Conformational Flexibility of the Chromophore
Descriptor: DI(HYDROXYETHYL)ETHER, GFP-like non-fluorescent chromoprotein
Authors:Wilmann, P.G, Petersen, J, Pettikiriarachchi, A, Buckle, A.M, Devenish, R.J, Prescott, M, Rossjohn, J.
Deposit date:2005-02-28
Release date:2005-05-17
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The 2.1A Crystal Structure of the Far-red Fluorescent Protein HcRed: Inherent Conformational Flexibility of the Chromophore
J.Mol.Biol., 349, 2005
1XXX
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BU of 1xxx by Molmil
Crystal structure of Dihydrodipicolinate Synthase (DapA, Rv2753c) from Mycobacterium tuberculosis
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CHLORIDE ION, Dihydrodipicolinate synthase, ...
Authors:Kefala, G, Panjikar, S, Janowski, R, Weiss, M.S, TB Structural Genomics Consortium (TBSGC)
Deposit date:2004-11-09
Release date:2006-02-14
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Crystal structure and kinetic study of dihydrodipicolinate synthase from Mycobacterium tuberculosis.
Biochem.J., 411, 2008
5IKX
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BU of 5ikx by Molmil
Crystal structure of the alpha-esterase-7 carboxyl esterase (dimer), E3, from Lucilia cuprina
Descriptor: Carboxylic ester hydrolase
Authors:Jackson, C, Fraser, N.
Deposit date:2016-03-04
Release date:2016-06-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Evolution of Protein Quaternary Structure in Response to Selective Pressure for Increased Thermostability.
J.Mol.Biol., 428, 2016
5HN1
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BU of 5hn1 by Molmil
Crystal structure of Interleukin-37
Descriptor: Interleukin-37, SULFATE ION
Authors:Ellisdon, A.M, Nold-Petry, C.A, Nold, M.F, Whisstock, J.C.
Deposit date:2016-01-17
Release date:2017-02-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Homodimerization attenuates the anti-inflammatory activity of interleukin-37.
Sci Immunol, 2, 2017
4R4U
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BU of 4r4u by Molmil
Crystal structure of acyl-CoA thioesterase tesB from Yersinia pestis in complex with coenzyme A
Descriptor: Acyl-CoA thioesterase II, COENZYME A, MALONIC ACID, ...
Authors:Swarbrick, C.M.D, Forwood, J.K.
Deposit date:2014-08-19
Release date:2015-04-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural and functional characterization of TesB from Yersinia pestis reveals a unique octameric arrangement of hotdog domains.
Acta Crystallogr.,Sect.D, 71, 2015
4DPP
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BU of 4dpp by Molmil
The structure of dihydrodipicolinate synthase 2 from Arabidopsis thaliana
Descriptor: Dihydrodipicolinate synthase 2, chloroplastic, SODIUM ION
Authors:Griffin, M.D.W, Billakanti, J.M, Gerrard, J.A, Dobson, R.C.J, Pearce, F.G.
Deposit date:2012-02-14
Release date:2012-07-18
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Characterisation of the first enzymes committed to lysine biosynthesis in Arabidopsis thaliana
Plos One, 7, 2012
4DPQ
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BU of 4dpq by Molmil
The structure of dihydrodipicolinate synthase 2 from Arabidopsis thaliana in complex with (S)-lysine
Descriptor: Dihydrodipicolinate synthase 2, chloroplastic, LYSINE, ...
Authors:Griffin, M.D.W, Billakanti, J.M, Gerrard, J.A, Dobson, R.C.J, Pearce, F.G.
Deposit date:2012-02-14
Release date:2012-07-18
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.202 Å)
Cite:Characterisation of the first enzymes committed to lysine biosynthesis in Arabidopsis thaliana
Plos One, 7, 2012
3C0J
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BU of 3c0j by Molmil
Structure of E. coli dihydrodipicolinate synthase complexed with hydroxypyruvate
Descriptor: Dihydrodipicolinate synthase, GLYCEROL, PHOSPHATE ION, ...
Authors:Dobson, R.C.J.
Deposit date:2008-01-21
Release date:2008-09-23
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Conserved main-chain peptide distortions: A proposed role for Ile203 in catalysis by dihydrodipicolinate synthase
Protein Sci., 17, 2008
3PB2
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BU of 3pb2 by Molmil
Characterisation of the first monomeric dihydrodipicolinate synthase variant reveals evolutionary insights
Descriptor: Dihydrodipicolinate synthase, GLYCEROL
Authors:Pearce, F.G, Dobson, R.C.J, Jameson, G.B.
Deposit date:2010-10-20
Release date:2011-11-23
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Characterization of monomeric dihydrodipicolinate synthase variant reveals the importance of substrate binding in optimizing oligomerization.
Biochim.Biophys.Acta, 1814, 2011

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