4NQ1

Legionella pneumophila dihydrodipicolinate synthase with first substrate pyruvate bound in the active site

Summary for 4NQ1

• Entry DOI: 10.2210/pdb4nq1/pdb
• Descriptor: 4-hydroxy-tetrahydrodipicolinate synthase, (4R)-2-METHYLPENTANE-2,4-DIOL, CHLORIDE ION, ... (6 entities in total)
• Functional Keywords: tim barrel, lysine biosynthesis, dihydrodipicolinate synthesis, pyruvate, lyase
• Biological source: Legionella pneumophila
• Cellular location: Cytoplasm (By similarity): D5T7I7
• Total number of polymer chains: 2
• Total formula weight: 63944.66

Authors

Siddiqui, T.,Paxman, J.J. (deposition date: 2013-11-23, release date: 2014-01-01, Last modification date: 2023-11-29)

• Primary citation: Siddiqui, T.,Paxman, J.J.,Dogovski, C.,Panjikar, S.,Perugini, M.A.; Legionella pneumophila DHDPS: The First Case of Non-Lysine Inhibition in a Gram-Negative Pathogen; To be Published,

Experimental method

X-RAY DIFFRACTION (1.65 Å)