8SQF
 
 | | OXA-48 bound to inhibitor CDD-2725 | | 分子名称: | (1M)-3'-(benzyloxy)-5-hydroxy[1,1'-biphenyl]-3,4'-dicarboxylic acid, BICARBONATE ION, Beta-lactamase | | 著者 | Park, S, Judge, A, Fan, J, Sankaran, B, Prasad, B.V.V, Palzkill, T. | | 登録日 | 2023-05-04 | | 公開日 | 2024-01-03 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Exploiting the Carboxylate-Binding Pocket of beta-Lactamase Enzymes Using a Focused DNA-Encoded Chemical Library.
J.Med.Chem., 67, 2024
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8SQG
 | | OXA-48 bound to inhibitor CDD-2801 | | 分子名称: | (1M)-3'-(benzyloxy)-5-[2-(methylamino)-2-oxoethoxy][1,1'-biphenyl]-3,4'-dicarboxylic acid, BICARBONATE ION, Beta-lactamase | | 著者 | Park, S, Judge, A, Fan, J, Sankaran, B, Palzkill, T. | | 登録日 | 2023-05-04 | | 公開日 | 2024-01-03 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | Exploiting the Carboxylate-Binding Pocket of beta-Lactamase Enzymes Using a Focused DNA-Encoded Chemical Library.
J.Med.Chem., 67, 2024
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8KCA
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1L5Z
 | | CRYSTAL STRUCTURE OF THE E121K SUBSTITUTION OF THE RECEIVER DOMAIN OF SINORHIZOBIUM MELILOTI DCTD | | 分子名称: | C4-DICARBOXYLATE TRANSPORT TRANSCRIPTIONAL REGULATORY PROTEIN DCTD, GLYCEROL, SULFATE ION | | 著者 | Park, S, Meyer, M, Jones, A.D, Yennawar, H.P, Yennawar, N.H, Nixon, B.T. | | 登録日 | 2002-03-08 | | 公開日 | 2002-10-23 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Two-component signaling in the AAA + ATPase DctD: binding Mg2+ and BeF3- selects between alternate dimeric states of the receiver domain
FASEB J., 16, 2002
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1L5Y
 | | CRYSTAL STRUCTURE OF MG2+ / BEF3-BOUND RECEIVER DOMAIN OF SINORHIZOBIUM MELILOTI DCTD | | 分子名称: | BERYLLIUM DIFLUORIDE, BERYLLIUM TETRAFLUORIDE ION, BERYLLIUM TRIFLUORIDE ION, ... | | 著者 | Park, S, Meyer, M, Jones, A.D, Yennawar, H.P, Yennawar, N.H, Nixon, B.T. | | 登録日 | 2002-03-08 | | 公開日 | 2002-10-23 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Two-component signaling in the AAA + ATPase DctD: binding Mg2+ and BeF3- selects between alternate dimeric states of the receiver domain
FASEB J., 16, 2002
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1OWA
 | | Solution Structural Studies on Human Erythrocyte Alpha Spectrin N Terminal Tetramerization Domain | | 分子名称: | Spectrin alpha chain, erythrocyte | | 著者 | Park, S, Caffrey, M.S, Johnson, M.E, Fung, L.W. | | 登録日 | 2003-03-28 | | 公開日 | 2004-03-30 | | 最終更新日 | 2022-02-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structural studies on human erythrocyte alpha-spectrin tetramerization site.
J.Biol.Chem., 278, 2003
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4FVC
 | | HmoB structure with heme | | 分子名称: | PROTOPORPHYRIN IX CONTAINING FE, Putative uncharacterized protein yhgC | | 著者 | Park, S. | | 登録日 | 2012-06-29 | | 公開日 | 2013-07-03 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Crystal structure of HmoB with Heme
To be Published
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2KNH
 | | The Solution structure of the eTAFH domain of AML1-ETO complexed with HEB peptide | | 分子名称: | Protein CBFA2T1, Transcription factor 12 | | 著者 | Park, S, Cierpicki, T, Tonelli, M, Bushweller, J.H. | | 登録日 | 2009-08-25 | | 公開日 | 2009-10-06 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of the AML1-ETO eTAFH domain-HEB peptide complex and its contribution to AML1-ETO activity.
Blood, 113, 2009
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2KYX
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2KYU
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2B86
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1ZC1
 | | Ufd1 exhibits the AAA-ATPase fold with two distinct ubiquitin interaction sites | | 分子名称: | Ubiquitin fusion degradation protein 1 | | 著者 | Park, S, Isaacson, R, Kim, H.T, Silver, P.A, Wagner, G. | | 登録日 | 2005-04-10 | | 公開日 | 2005-07-26 | | 最終更新日 | 2022-03-02 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Ufd1 Exhibits the AAA-ATPase Fold with Two Distinct Ubiquitin Interaction Sites
Structure, 13, 2005
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5U7G
 | | Crystal Structure of the Catalytic Core of CBP | | 分子名称: | CREB-binding protein, ZINC ION | | 著者 | Park, S, Stanfield, R.L, Martinez-Yamout, M.M, Dyson, H.J, Wilson, I.A, Wright, P.E. | | 登録日 | 2016-12-12 | | 公開日 | 2017-06-21 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.401 Å) | | 主引用文献 | Role of the CBP catalytic core in intramolecular SUMOylation and control of histone H3 acetylation.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6L9X
 | | Xenons in frog EPDR1 | | 分子名称: | Ependymin-related 1, XENON | | 著者 | Park, S. | | 登録日 | 2019-11-11 | | 公開日 | 2020-11-11 | | 最終更新日 | 2021-05-26 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | De novo Phasing Xenons Observed in the Frog Ependymin-Related Protein
Crystals, 10, 2020
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6J10
 | | Ciclopirox inhibits Hepatitis B Virus secretion by blocking capsid assembly | | 分子名称: | 6-cyclohexyl-4-methyl-1-oxidanyl-pyridin-2-one, Capsid protein | | 著者 | Park, S, Jin, M.S, Cho, Y, Kang, J, Kim, S, Park, M, Park, H, Kim, J, Park, S, Hwang, J, Kim, Y, Kim, Y.J. | | 登録日 | 2018-12-27 | | 公開日 | 2019-04-17 | | 最終更新日 | 2019-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Ciclopirox inhibits Hepatitis B Virus secretion by blocking capsid assembly.
Nat Commun, 10, 2019
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4NJD
 | | Structure of p21-activated kinase 4 with a novel inhibitor KY-04031 | | 分子名称: | N-(1H-indazol-5-yl)-N'-[2-(1H-indol-3-yl)ethyl]-6-methoxy-1,3,5-triazine-2,4-diamine, Serine/threonine-protein kinase PAK 4 | | 著者 | Park, S. | | 登録日 | 2013-11-09 | | 公開日 | 2014-05-21 | | 最終更新日 | 2022-08-24 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Discovery and the structural basis of a novel p21-activated kinase 4 inhibitor.
Cancer Lett., 349, 2014
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6UUP
 | | Structure of anti-hCD33 conditional scFv | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Anti-CD33 conditional scFv, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Kimberlin, C.R, Park, S. | | 登録日 | 2019-10-31 | | 公開日 | 2020-11-04 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.20001864 Å) | | 主引用文献 | Direct control of CAR T cells through small molecule-regulated antibodies.
Nat Commun, 12, 2021
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6UY3
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3TVZ
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2HP7
 | | Structure of FliM provides insight into assembly of the switch complex in the bacterial flagella motor | | 分子名称: | Flagellar motor switch protein FliM | | 著者 | Crane, B.R, Park, S, Lowder, B, Bilwes, A.M, Blair, D.F. | | 登録日 | 2006-07-17 | | 公開日 | 2006-08-08 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure of FliM provides insight into assembly of the switch complex in the bacterial flagella motor.
Proc.Natl.Acad.Sci.Usa, 103, 2006
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6JLA
 | | Crystal structure of a mouse ependymin related protein | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Mammalian ependymin-related protein 1 | | 著者 | Park, S. | | 登録日 | 2019-03-04 | | 公開日 | 2020-03-04 | | 最終更新日 | 2020-09-16 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structures of three ependymin-related proteins suggest their function as a hydrophobic molecule binder.
Iucrj, 6, 2019
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5U9B
 | | Solution structure of the zinc fingers 1 and 2 of MBNL1 in complex with human cardiac troponin T pre-mRNA | | 分子名称: | Muscleblind-like protein 1, RNA (5'-R(P*GP*UP*CP*UP*CP*GP*CP*UP*UP*UP*UP*CP*CP*CP*C)-3'), ZINC ION | | 著者 | Phukan, P.D, Park, S, Martinez-Yamout, M.M, Zeeb, M, Dyson, H.J, Wright, P.E. | | 登録日 | 2016-12-15 | | 公開日 | 2017-08-02 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural Basis for Interaction of the Tandem Zinc Finger Domains of Human Muscleblind with Cognate RNA from Human Cardiac Troponin T.
Biochemistry, 56, 2017
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5U6L
 | | Solution structure of the zinc fingers 3 and 4 of MBNL1 | | 分子名称: | Muscleblind-like protein 1, ZINC ION | | 著者 | Phukan, P.D, Park, S, Martinez-Yamout, M.M, Zeeb, M, Dyson, H.J, Wright, P.E. | | 登録日 | 2016-12-08 | | 公開日 | 2017-08-02 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural Basis for Interaction of the Tandem Zinc Finger Domains of Human Muscleblind with Cognate RNA from Human Cardiac Troponin T.
Biochemistry, 56, 2017
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5U6H
 | | Solution structure of the zinc fingers 1 and 2 of MBNL1 | | 分子名称: | Muscleblind-like protein 1, ZINC ION | | 著者 | Phukan, P.D, Park, S, Martinez-Yamout, M.M, Zeeb, M, Dyson, H.J, Wright, P.E. | | 登録日 | 2016-12-08 | | 公開日 | 2017-08-02 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural Basis for Interaction of the Tandem Zinc Finger Domains of Human Muscleblind with Cognate RNA from Human Cardiac Troponin T.
Biochemistry, 56, 2017
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1CQS
 | | CRYSTAL STRUCTURE OF D103E MUTANT WITH EQUILENINEOF KSI IN PSEUDOMONAS PUTIDA | | 分子名称: | EQUILENIN, PROTEIN : KETOSTEROID ISOMERASE | | 著者 | Choi, G, Ha, N.C, Kim, S.W, Kim, D.H, Park, S, Oh, B.H, Choi, K.Y. | | 登録日 | 1999-08-11 | | 公開日 | 2003-06-17 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Asp-99 donates a hydrogen bond not to Tyr-14 but to the steroid directly
in the catalytic mechanism of Delta 5-3-ketosteroid isomerase from
Pseudomonas putida biotype B
Biochemistry, 39, 2000
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