6UY3
Structure of anti-hCD33 conditional scFv with methotrexate
Summary for 6UY3
Entry DOI | 10.2210/pdb6uy3/pdb |
Related | 3F12 6uup |
Descriptor | Anti-CD33 conditional scFv, PHOSPHATE ION, GLYCEROL, ... (5 entities in total) |
Functional Keywords | conditional car, mtx, cd33, conditional antibody, antitumor protein |
Biological source | Camelidae mixed library |
Total number of polymer chains | 1 |
Total formula weight | 29364.86 |
Authors | Kimberlin, C.R.,Park, S. (deposition date: 2019-11-11, release date: 2020-11-18, Last modification date: 2023-10-11) |
Primary citation | Park, S.,Pascua, E.,Lindquist, K.C.,Kimberlin, C.,Deng, X.,Mak, Y.S.L.,Melton, Z.,Johnson, T.O.,Lin, R.,Boldajipour, B.,Abraham, R.T.,Pons, J.,Sasu, B.J.,Van Blarcom, T.J.,Chaparro-Riggers, J. Direct control of CAR T cells through small molecule-regulated antibodies. Nat Commun, 12:710-710, 2021 Cited by PubMed: 33514714DOI: 10.1038/s41467-020-20671-6 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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