6UUP

Structure of anti-hCD33 conditional scFv

Summary for 6UUP

• Entry DOI: 10.2210/pdb6uup/pdb
• Related: 3F12
• Descriptor: Anti-CD33 conditional scFv, GLYCEROL, DI(HYDROXYETHYL)ETHER, ... (6 entities in total)
• Functional Keywords: conditional car, mtx, cd33, conditional antibody, antitumor protein
• Biological source: Camelidae mixed library
• Total number of polymer chains: 4
• Total formula weight: 116519.62

Authors

Kimberlin, C.R.,Park, S. (deposition date: 2019-10-31, release date: 2020-11-04, Last modification date: 2023-10-11)

• Primary citation: Park, S.,Pascua, E.,Lindquist, K.C.,Kimberlin, C.,Deng, X.,Mak, Y.S.L.,Melton, Z.,Johnson, T.O.,Lin, R.,Boldajipour, B.,Abraham, R.T.,Pons, J.,Sasu, B.J.,Van Blarcom, T.J.,Chaparro-Riggers, J.; Direct control of CAR T cells through small molecule-regulated antibodies.; Nat Commun, 12:710-710, 2021; PubMed: 33514714; DOI: 10.1038/s41467-020-20671-6

Experimental method

X-RAY DIFFRACTION (2.2000186 Å)