8KCA
 
 | |
8SQF
 | | OXA-48 bound to inhibitor CDD-2725 | | Descriptor: | (1M)-3'-(benzyloxy)-5-hydroxy[1,1'-biphenyl]-3,4'-dicarboxylic acid, BICARBONATE ION, Beta-lactamase | | Authors: | Park, S, Judge, A, Fan, J, Sankaran, B, Prasad, B.V.V, Palzkill, T. | | Deposit date: | 2023-05-04 | | Release date: | 2024-01-03 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Exploiting the Carboxylate-Binding Pocket of beta-Lactamase Enzymes Using a Focused DNA-Encoded Chemical Library.
J.Med.Chem., 67, 2024
|
|
8SQG
 | | OXA-48 bound to inhibitor CDD-2801 | | Descriptor: | (1M)-3'-(benzyloxy)-5-[2-(methylamino)-2-oxoethoxy][1,1'-biphenyl]-3,4'-dicarboxylic acid, BICARBONATE ION, Beta-lactamase | | Authors: | Park, S, Judge, A, Fan, J, Sankaran, B, Palzkill, T. | | Deposit date: | 2023-05-04 | | Release date: | 2024-01-03 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.03 Å) | | Cite: | Exploiting the Carboxylate-Binding Pocket of beta-Lactamase Enzymes Using a Focused DNA-Encoded Chemical Library.
J.Med.Chem., 67, 2024
|
|
5U7G
 | | Crystal Structure of the Catalytic Core of CBP | | Descriptor: | CREB-binding protein, ZINC ION | | Authors: | Park, S, Stanfield, R.L, Martinez-Yamout, M.M, Dyson, H.J, Wilson, I.A, Wright, P.E. | | Deposit date: | 2016-12-12 | | Release date: | 2017-06-21 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.401 Å) | | Cite: | Role of the CBP catalytic core in intramolecular SUMOylation and control of histone H3 acetylation.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
1ZC1
 | | Ufd1 exhibits the AAA-ATPase fold with two distinct ubiquitin interaction sites | | Descriptor: | Ubiquitin fusion degradation protein 1 | | Authors: | Park, S, Isaacson, R, Kim, H.T, Silver, P.A, Wagner, G. | | Deposit date: | 2005-04-10 | | Release date: | 2005-07-26 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Ufd1 Exhibits the AAA-ATPase Fold with Two Distinct Ubiquitin Interaction Sites
Structure, 13, 2005
|
|
4FVC
 | | HmoB structure with heme | | Descriptor: | PROTOPORPHYRIN IX CONTAINING FE, Putative uncharacterized protein yhgC | | Authors: | Park, S. | | Deposit date: | 2012-06-29 | | Release date: | 2013-07-03 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Crystal structure of HmoB with Heme
To be Published
|
|
2B86
 | |
1L5Z
 | | CRYSTAL STRUCTURE OF THE E121K SUBSTITUTION OF THE RECEIVER DOMAIN OF SINORHIZOBIUM MELILOTI DCTD | | Descriptor: | C4-DICARBOXYLATE TRANSPORT TRANSCRIPTIONAL REGULATORY PROTEIN DCTD, GLYCEROL, SULFATE ION | | Authors: | Park, S, Meyer, M, Jones, A.D, Yennawar, H.P, Yennawar, N.H, Nixon, B.T. | | Deposit date: | 2002-03-08 | | Release date: | 2002-10-23 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Two-component signaling in the AAA + ATPase DctD: binding Mg2+ and BeF3- selects between alternate dimeric states of the receiver domain
FASEB J., 16, 2002
|
|
1L5Y
 | | CRYSTAL STRUCTURE OF MG2+ / BEF3-BOUND RECEIVER DOMAIN OF SINORHIZOBIUM MELILOTI DCTD | | Descriptor: | BERYLLIUM DIFLUORIDE, BERYLLIUM TETRAFLUORIDE ION, BERYLLIUM TRIFLUORIDE ION, ... | | Authors: | Park, S, Meyer, M, Jones, A.D, Yennawar, H.P, Yennawar, N.H, Nixon, B.T. | | Deposit date: | 2002-03-08 | | Release date: | 2002-10-23 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Two-component signaling in the AAA + ATPase DctD: binding Mg2+ and BeF3- selects between alternate dimeric states of the receiver domain
FASEB J., 16, 2002
|
|
1OWA
 | | Solution Structural Studies on Human Erythrocyte Alpha Spectrin N Terminal Tetramerization Domain | | Descriptor: | Spectrin alpha chain, erythrocyte | | Authors: | Park, S, Caffrey, M.S, Johnson, M.E, Fung, L.W. | | Deposit date: | 2003-03-28 | | Release date: | 2004-03-30 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution structural studies on human erythrocyte alpha-spectrin tetramerization site.
J.Biol.Chem., 278, 2003
|
|
6L9X
 | | Xenons in frog EPDR1 | | Descriptor: | Ependymin-related 1, XENON | | Authors: | Park, S. | | Deposit date: | 2019-11-11 | | Release date: | 2020-11-11 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | De novo Phasing Xenons Observed in the Frog Ependymin-Related Protein
Crystals, 10, 2020
|
|
2KYX
 | | Solution structure of the RRM domain of CYP33 | | Descriptor: | Peptidyl-prolyl cis-trans isomerase E | | Authors: | Park, S, Bushweller, J.H. | | Deposit date: | 2010-06-09 | | Release date: | 2010-08-25 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | The PHD3 domain of MLL acts as a CYP33-regulated switch between MLL-mediated activation and repression .
Biochemistry, 49, 2010
|
|
2KNH
 | | The Solution structure of the eTAFH domain of AML1-ETO complexed with HEB peptide | | Descriptor: | Protein CBFA2T1, Transcription factor 12 | | Authors: | Park, S, Cierpicki, T, Tonelli, M, Bushweller, J.H. | | Deposit date: | 2009-08-25 | | Release date: | 2009-10-06 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Structure of the AML1-ETO eTAFH domain-HEB peptide complex and its contribution to AML1-ETO activity.
Blood, 113, 2009
|
|
2KYU
 | | The solution structure of the PHD3 finger of MLL | | Descriptor: | Histone-lysine N-methyltransferase MLL, ZINC ION | | Authors: | Park, S, Bushweller, J.H. | | Deposit date: | 2010-06-08 | | Release date: | 2010-08-25 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | The PHD3 domain of MLL acts as a CYP33-regulated switch between MLL-mediated activation and repression.
Biochemistry, 49, 2010
|
|
1BPI
 | |
1JBC
 | | CONCANAVALIN A | | Descriptor: | CALCIUM ION, CONCANAVALIN A, MANGANESE (II) ION | | Authors: | Parkin, S, Rupp, B, Hope, H. | | Deposit date: | 1996-08-23 | | Release date: | 1997-02-12 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (1.15 Å) | | Cite: | Atomic resolution structure of concanavalin A at 120 K.
Acta Crystallogr.,Sect.D, 52, 1996
|
|
6UUP
 | | Structure of anti-hCD33 conditional scFv | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Anti-CD33 conditional scFv, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Kimberlin, C.R, Park, S. | | Deposit date: | 2019-10-31 | | Release date: | 2020-11-04 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.20001864 Å) | | Cite: | Direct control of CAR T cells through small molecule-regulated antibodies.
Nat Commun, 12, 2021
|
|
8XTA
 | | Clostridioides difficile MarR (WP_003434724) | | Descriptor: | MarR family transcriptional regulator | | Authors: | Park, S, Kwon, N. | | Deposit date: | 2024-01-10 | | Release date: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of a Clostridioides difficile multiple antibiotic resistance regulator (MarR) CD0473 suggests a potential redox-regulated function.
Int.J.Biol.Macromol., 280, 2024
|
|
8XU0
 | | Clostridioides difficile MarR (WP_003434724) with salicylate | | Descriptor: | 2-HYDROXYBENZOIC ACID, MarR | | Authors: | Park, S, Kwon, N. | | Deposit date: | 2024-01-12 | | Release date: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.29 Å) | | Cite: | Crystal structure of a Clostridioides difficile multiple antibiotic resistance regulator (MarR) CD0473 suggests a potential redox-regulated function.
Int.J.Biol.Macromol., 280, 2024
|
|
8XT8
 | | Clostridioides difficile MarR (WP_003434724) with Hg-bound | | Descriptor: | MERCURY (II) ION, MarR family transcriptional regulator | | Authors: | Park, S, Kwon, N. | | Deposit date: | 2024-01-10 | | Release date: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of a Clostridioides difficile multiple antibiotic resistance regulator (MarR) CD0473 suggests a potential redox-regulated function.
Int.J.Biol.Macromol., 280, 2024
|
|
6UY3
 | |
6J10
 | | Ciclopirox inhibits Hepatitis B Virus secretion by blocking capsid assembly | | Descriptor: | 6-cyclohexyl-4-methyl-1-oxidanyl-pyridin-2-one, Capsid protein | | Authors: | Park, S, Jin, M.S, Cho, Y, Kang, J, Kim, S, Park, M, Park, H, Kim, J, Park, S, Hwang, J, Kim, Y, Kim, Y.J. | | Deposit date: | 2018-12-27 | | Release date: | 2019-04-17 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Ciclopirox inhibits Hepatitis B Virus secretion by blocking capsid assembly.
Nat Commun, 10, 2019
|
|
4NJD
 | | Structure of p21-activated kinase 4 with a novel inhibitor KY-04031 | | Descriptor: | N-(1H-indazol-5-yl)-N'-[2-(1H-indol-3-yl)ethyl]-6-methoxy-1,3,5-triazine-2,4-diamine, Serine/threonine-protein kinase PAK 4 | | Authors: | Park, S. | | Deposit date: | 2013-11-09 | | Release date: | 2014-05-21 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Discovery and the structural basis of a novel p21-activated kinase 4 inhibitor.
Cancer Lett., 349, 2014
|
|
3TVZ
 | | Structure of Bacillus subtilis HmoB | | Descriptor: | Putative uncharacterized protein yhgC | | Authors: | Choe, J, Choi, S, Park, S. | | Deposit date: | 2011-09-21 | | Release date: | 2012-07-11 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Bacillus subtilis HmoB is a heme oxygenase with a novel structure.
Bmb Rep, 45, 2012
|
|
6JLA
 | | Crystal structure of a mouse ependymin related protein | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Mammalian ependymin-related protein 1 | | Authors: | Park, S. | | Deposit date: | 2019-03-04 | | Release date: | 2020-03-04 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structures of three ependymin-related proteins suggest their function as a hydrophobic molecule binder.
Iucrj, 6, 2019
|
|
