3ANW
 
 | | A protein complex essential initiation of DNA replication | | 分子名称: | Putative uncharacterized protein | | 著者 | Oyama, T, Shirai, T, Nagasawa, N, Ishino, Y, Morikawa, K. | | 登録日 | 2010-09-10 | | 公開日 | 2011-07-27 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Architectures of archaeal GINS complexes, essential DNA replication initiation factors
Bmc Biol., 9, 2011
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2ZJ2
 | | Archaeal DNA helicase Hjm apo state in form 1 | | 分子名称: | Putative ski2-type helicase, SULFATE ION | | 著者 | Oyama, T, Oka, H, Fujikane, R, Ishino, Y, Morikawa, K. | | 登録日 | 2008-02-29 | | 公開日 | 2009-02-10 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Atomic structures and functional implications of the archaeal RecQ-like helicase Hjm
Bmc Struct.Biol., 9, 2009
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2ZJ8
 | | Archaeal DNA helicase Hjm apo state in form 2 | | 分子名称: | Putative ski2-type helicase | | 著者 | Oyama, T, Oka, H, Fujikane, R, Ishino, Y, Morikawa, K. | | 登録日 | 2008-02-29 | | 公開日 | 2009-02-10 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Atomic structures and functional implications of the archaeal RecQ-like helicase Hjm
Bmc Struct.Biol., 9, 2009
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2ZJ5
 | | Archaeal DNA helicase Hjm complexed with ADP in form 1 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Putative ski2-type helicase, SULFATE ION | | 著者 | Oyama, T, Oka, H, Fujikane, R, Ishino, Y, Morikawa, K. | | 登録日 | 2008-02-29 | | 公開日 | 2009-02-10 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Atomic structures and functional implications of the archaeal RecQ-like helicase Hjm
Bmc Struct.Biol., 9, 2009
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2ZJA
 | | Archaeal DNA helicase Hjm complexed with AMPPCP in form 2 | | 分子名称: | PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Putative ski2-type helicase | | 著者 | Oyama, T, Oka, H, Fujikane, R, Ishino, Y, Morikawa, K. | | 登録日 | 2008-02-29 | | 公開日 | 2009-02-10 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Atomic structures and functional implications of the archaeal RecQ-like helicase Hjm
Bmc Struct.Biol., 9, 2009
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4QRF
 | | Crystal structure of V30M mutant human transthyretin complexed with caffeic acid phenethyl ester | | 分子名称: | 2-phenylethyl (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoate, Transthyretin | | 著者 | Yokoyama, T, Kosaka, Y, Mizuguchi, M. | | 登録日 | 2014-06-30 | | 公開日 | 2014-11-26 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Inhibitory Activities of Propolis and Its Promising Component, Caffeic Acid Phenethyl Ester, against Amyloidogenesis of Human Transthyretin
J.Med.Chem., 57, 2014
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5CG5
 | | Neutron crystal structure of human farnesyl pyrophosphate synthase in complex with risedronate | | 分子名称: | 1-HYDROXY-2-(3-PYRIDINYL)ETHYLIDENE BIS-PHOSPHONIC ACID, Farnesyl pyrophosphate synthase, MAGNESIUM ION | | 著者 | Yokoyama, T, Mizuguchi, M, Ostermann, A, Kusaka, K, Niimura, N, Schrader, T.E, Tanaka, I. | | 登録日 | 2015-07-09 | | 公開日 | 2015-10-14 | | 最終更新日 | 2024-04-03 | | 実験手法 | NEUTRON DIFFRACTION (1.402 Å), X-RAY DIFFRACTION | | 主引用文献 | Protonation State and Hydration of Bisphosphonate Bound to Farnesyl Pyrophosphate Synthase
J.Med.Chem., 58, 2015
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5CG6
 | | Neutron crystal structure of human farnesyl pyrophosphate synthase in complex with risedronate and isopentenyl pyrophosphate | | 分子名称: | 1-HYDROXY-2-(3-PYRIDINYL)ETHYLIDENE BIS-PHOSPHONIC ACID, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Farnesyl pyrophosphate synthase, ... | | 著者 | Yokoyama, T, Mizuguchi, M, Ostermann, A, Kusaka, K, Niimura, N, Schrader, T.E, Tanaka, I. | | 登録日 | 2015-07-09 | | 公開日 | 2015-10-14 | | 最終更新日 | 2024-04-03 | | 実験手法 | NEUTRON DIFFRACTION (1.7 Å), X-RAY DIFFRACTION | | 主引用文献 | Protonation State and Hydration of Bisphosphonate Bound to Farnesyl Pyrophosphate Synthase
J.Med.Chem., 58, 2015
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6IP6
 | | Cryo-EM structure of the CMV-stalled human 80S ribosome with HCV IRES (Structure iii) | | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | | 著者 | Yokoyama, T, Shigematsu, H, Shirouzu, M, Imataka, H, Ito, T. | | 登録日 | 2018-11-02 | | 公開日 | 2019-05-29 | | 最終更新日 | 2019-11-06 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | HCV IRES Captures an Actively Translating 80S Ribosome.
Mol.Cell, 74, 2019
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6IP8
 | | Cryo-EM structure of the HCV IRES dependently initiated CMV-stalled 80S ribosome (Structure iv) | | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | | 著者 | Yokoyama, T, Shigematsu, H, Shirouzu, M, Imataka, H, Ito, T. | | 登録日 | 2018-11-02 | | 公開日 | 2019-05-29 | | 最終更新日 | 2019-11-06 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | HCV IRES Captures an Actively Translating 80S Ribosome.
Mol.Cell, 74, 2019
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6IP5
 | | Cryo-EM structure of the CMV-stalled human 80S ribosome (Structure ii) | | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | | 著者 | Yokoyama, T, Shigematsu, H, Shirouzu, M, Imataka, H, Ito, T. | | 登録日 | 2018-11-02 | | 公開日 | 2019-05-29 | | 最終更新日 | 2019-11-06 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | HCV IRES Captures an Actively Translating 80S Ribosome.
Mol.Cell, 74, 2019
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3J0E
 | | Models for the T. thermophilus ribosome recycling factor and the E. coli elongation factor G bound to the E. coli post-termination complex | | 分子名称: | 30S ribosomal protein S12, Elongation factor G, Ribosome-recycling factor, ... | | 著者 | Yokoyama, T, Shaikh, T.R, Iwakura, N, Kaji, H, Kaji, A, Agrawal, R.K. | | 登録日 | 2011-06-29 | | 公開日 | 2012-04-25 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (9.9 Å) | | 主引用文献 | Structural insights into initial and intermediate steps of the ribosome-recycling process.
Embo J., 31, 2012
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4Y9B
 | | Crystal structure of V30M mutated transthyretin in complex with alpha-mangostin | | 分子名称: | 1,3,6-trihydroxy-7-methoxy-2,8-bis(3-methylbut-2-en-1-yl)-9H-xanthen-9-one, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Yokoyama, T, Mizuguchi, M. | | 登録日 | 2015-02-17 | | 公開日 | 2015-09-09 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Discovery of gamma-Mangostin as an Amyloidogenesis Inhibitor
Sci Rep, 5, 2015
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4Y9F
 | | Crystal structure of V30M mutated transthyretin with bromide in complex with gamma-mangostin | | 分子名称: | 1,3,6,7-tetrahydroxy-2,8-bis(3-methylbut-2-en-1-yl)-9H-xanthen-9-one, BROMIDE ION, Transthyretin | | 著者 | Yokoyama, T, Mizuguchi, M. | | 登録日 | 2015-02-17 | | 公開日 | 2015-09-09 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Discovery of gamma-Mangostin as an Amyloidogenesis Inhibitor
Sci Rep, 5, 2015
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8W42
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8W44
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8W46
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8W48
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8W43
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8W45
 | | X-ray crystal structure of V30M-TTR in complex with pinostilbene | | 分子名称: | 3-[(E)-2-(4-hydroxyphenyl)ethenyl]-5-methoxy-phenol, SODIUM ION, Transthyretin | | 著者 | Yokoyama, T. | | 登録日 | 2023-08-23 | | 公開日 | 2023-11-22 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Resveratrol Derivatives Inhibit Transthyretin Fibrillization: Structural Insights into the Interactions between Resveratrol Derivatives and Transthyretin.
J.Med.Chem., 66, 2023
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8W47
 | | X-ray crystal structure of V30M-TTR in complex with isorhapontigenin | | 分子名称: | 5-[(~{E})-2-(3-methoxy-4-oxidanyl-phenyl)ethenyl]benzene-1,3-diol, SODIUM ION, Transthyretin | | 著者 | Yokoyama, T. | | 登録日 | 2023-08-23 | | 公開日 | 2023-11-22 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Resveratrol Derivatives Inhibit Transthyretin Fibrillization: Structural Insights into the Interactions between Resveratrol Derivatives and Transthyretin.
J.Med.Chem., 66, 2023
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5H0Z
 | | Crystal structure of P113A mutated human transthyretin | | 分子名称: | CHLORIDE ION, SULFATE ION, Transthyretin | | 著者 | Yokoyama, T, Hanawa, Y, Obita, T, Mizuguchi, M. | | 登録日 | 2016-10-07 | | 公開日 | 2017-06-14 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.735 Å) | | 主引用文献 | Stability and crystal structures of His88 mutant human transthyretins
FEBS Lett., 591, 2017
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5H0V
 | | Crystal structure of H88A mutated human transthyretin | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, MAGNESIUM ION, Transthyretin | | 著者 | Yokoyama, T, Hanawa, Y, Obita, T, Mizuguchi, M. | | 登録日 | 2016-10-07 | | 公開日 | 2017-06-14 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | Stability and crystal structures of His88 mutant human transthyretins
FEBS Lett., 591, 2017
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5H0X
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5H0W
 | | Crystal structure of H88F mutated human transthyretin | | 分子名称: | SULFATE ION, Transthyretin | | 著者 | Yokoyama, T, Hanawa, Y, Obita, T, Mizuguchi, M. | | 登録日 | 2016-10-07 | | 公開日 | 2017-06-14 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.904 Å) | | 主引用文献 | Stability and crystal structures of His88 mutant human transthyretins
FEBS Lett., 591, 2017
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