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1WAQ
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BU of 1waq by Molmil
Crystal structure of human Growth and Differentiation Factor 5 (GDF-5)
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, GROWTH/DIFFERENTIATION FACTOR 5
著者Mueller, T.D, Nickel, J, Sebald, W.
登録日2004-10-27
公開日2005-05-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献A Single Residue of Gdf-5 Defines Binding Specificity to Bmp Receptor Ib.
J.Mol.Biol., 349, 2005
4AJV
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BU of 4ajv by Molmil
Structure of mouse ZP-C domain of TGF-Beta-Receptor-3
分子名称: TRANSFORMING GROWTH FACTOR BETA RECEPTOR TYPE 3
著者Diestel, U, Resch, M, Meinhardt, K, Weiler, S, Hellmann, T.V, Nickel, J, Eichler, J, Muller, Y.A.
登録日2012-02-20
公開日2013-02-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Identification of a Novel Tgf-Beta-Binding Site in the Zona Pellucida C-Terminal (Zp-C) Domain of Tgf-Beta-Receptor-3 (Tgfr-3).
Plos One, 8, 2013
1REU
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BU of 1reu by Molmil
Structure of the bone morphogenetic protein 2 mutant L51P
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, bone morphogenetic protein 2
著者Keller, S, Nickel, J, Zhang, J.-L, Sebald, W, Mueller, T.D.
登録日2003-11-07
公開日2004-05-04
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Molecular recognition of BMP-2 and BMP receptor IA.
Nat.Struct.Mol.Biol., 11, 2004
1REW
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BU of 1rew by Molmil
Structural refinement of the complex of bone morphogenetic protein 2 and its type IA receptor
分子名称: bone morphogenetic protein 2, bone morphogenetic protein receptor type IA
著者Keller, S, Nickel, J, Zhang, J.-L, Sebald, W, Mueller, T.D.
登録日2003-11-07
公開日2004-05-04
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.863 Å)
主引用文献Molecular recognition of BMP-2 and BMP receptor IA.
Nat.Struct.Mol.Biol., 11, 2004
3QT2
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BU of 3qt2 by Molmil
Structure of a cytokine ligand-receptor complex
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Interleukin-5, Interleukin-5 receptor subunit alpha, ...
著者Mueller, T.D, Patino, E, Kotzsch, A, Saremba, S, Nickel, J, Schmitz, W, Sebald, W.
登録日2011-02-22
公開日2012-02-01
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structure Analysis of the IL-5 Ligand-Receptor Complex Reveals a Wrench-like Architecture for IL-5Ralpha.
Structure, 19, 2011
3QB4
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BU of 3qb4 by Molmil
Crystal structure of a TGF-beta ligand-receptor complex
分子名称: Bone morphogenetic protein receptor type-1A, Growth/differentiation factor 5
著者Mueller, T.D, Nickel, J, Sebald, W.
登録日2011-01-12
公開日2012-03-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献GDF-5 can act as a context-dependent BMP-2 antagonist.
Bmc Biol., 13, 2015
2QJ9
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BU of 2qj9 by Molmil
Crystal structure analysis of BMP-2 in complex with BMPR-IA variant B1
分子名称: Bone morphogenetic protein 2, Bone morphogenetic protein receptor type IA
著者Kotzsch, A, Mueller, T.D.
登録日2007-07-06
公開日2008-01-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Structure analysis of bone morphogenetic protein-2 type I receptor complexes reveals a mechanism of receptor inactivation in juvenile polyposis syndrome.
J.Biol.Chem., 283, 2008
2QJA
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BU of 2qja by Molmil
Crystal structure analysis of BMP-2 in complex with BMPR-IA variant B12
分子名称: Bone morphogenetic protein 2, Bone morphogenetic protein receptor type IA
著者Kotzsch, A, Mueller, T.D.
登録日2007-07-06
公開日2008-01-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure analysis of bone morphogenetic protein-2 type I receptor complexes reveals a mechanism of receptor inactivation in juvenile polyposis syndrome.
J.Biol.Chem., 283, 2008
2QJB
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BU of 2qjb by Molmil
Crystal structure analysis of BMP-2 in complex with BMPR-IA variant IA/IB
分子名称: Bone morphogenetic protein 2, Bone morphogenetic protein receptor type IA, CHLORIDE ION
著者Kotzsch, A, Mueller, T.D.
登録日2007-07-06
公開日2008-01-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure analysis of bone morphogenetic protein-2 type I receptor complexes reveals a mechanism of receptor inactivation in juvenile polyposis syndrome.
J.Biol.Chem., 283, 2008
3EVS
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BU of 3evs by Molmil
Crystal structure of the GDF-5:BMP receptor IB complex.
分子名称: Bone morphogenetic protein receptor type-1B, Growth/differentiation factor 5
著者Kotzsch, A, Mueller, T.D.
登録日2008-10-13
公開日2009-03-10
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure analysis reveals a spring-loaded latch as molecular mechanism for GDF-5-type I receptor specificity.
Embo J., 28, 2009
2R53
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BU of 2r53 by Molmil
Crystal structure analysis of Bone Morphogenetic Protein-6 variant B2 (B2-BMP-6)
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Bone morphogenetic protein 6
著者Mueller, T.D, Sebald, W.
登録日2007-09-03
公開日2008-01-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Type I receptor binding of bone morphogenetic protein 6 is dependent on N-glycosylation of the ligand.
Febs J., 275, 2007
2R52
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BU of 2r52 by Molmil
Crystal structure analysis of Bone Morphogenetic Protein-6 (BMP-6)
分子名称: Bone morphogenetic protein 6, ISOPROPYL ALCOHOL
著者Mueller, T.D, Sebald, W, Saremba, S.
登録日2007-09-03
公開日2008-01-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Type I receptor binding of bone morphogenetic protein 6 is dependent on N-glycosylation of the ligand.
Febs J., 275, 2007
2K3G
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BU of 2k3g by Molmil
NMR structure analysis of a BMP receptor
分子名称: Bone morphogenetic protein receptor type-1A
著者Klages, J, Kotzsch, A, Mueller, T, Kessler, H.
登録日2008-05-07
公開日2008-12-16
最終更新日2021-10-20
実験手法SOLUTION NMR
主引用文献The solution structure of BMPR-IA reveals a local disorder-to-order transition upon BMP-2 binding.
Biochemistry, 47, 2008
2H62
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BU of 2h62 by Molmil
Crystal structure of a ternary ligand-receptor complex of BMP-2
分子名称: Acvr2b protein, Bone morphogenetic protein 2, Bone morphogenetic protein receptor type IA
著者Mueller, T.D.
登録日2006-05-30
公開日2007-04-10
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献A silent H-bond can be mutationally activated for high-affinity interaction of BMP-2 and activin type IIB receptor.
Bmc Struct.Biol., 7, 2007
2H64
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BU of 2h64 by Molmil
Crystal structure of a ternary ligand-receptor complex of BMP-2
分子名称: Acvr2b protein, Bone morphogenetic protein 2, Bone morphogenetic protein receptor type IA
著者Mueller, T.D, Sebald, W, Weber, D.
登録日2006-05-30
公開日2007-04-10
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献A silent H-bond can be mutationally activated for high-affinity interaction of BMP-2 and activin type IIB receptor.
Bmc Struct.Biol., 7, 2007
6H41
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BU of 6h41 by Molmil
Structure of the complex of the IL-5 inhibitory peptide AF17121 bound to the IL-5 receptor IL-5Ralpha
分子名称: Interleukin-5 receptor subunit alpha, VAL-ASP-GLU-CYS-TRP-ARG-ILE-ILE-ALA-SER-HIS-THR-TRP-PHE-CYS-ALA-GLU-GLU
著者Mueller, T.D, Scheide, J.P.
登録日2018-07-20
公開日2018-12-26
最終更新日2019-02-27
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural Basis of Interleukin-5 Inhibition by the Small Cyclic Peptide AF17121.
J. Mol. Biol., 431, 2019
2B8Z
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BU of 2b8z by Molmil
Crystal structure of the interleukin-4 variant R85A
分子名称: Interleukin-4, SULFATE ION
著者Kraich, M, Klein, M, Patino, E, Harrer, H, Sebald, W, Mueller, T.D.
登録日2005-10-10
公開日2006-05-30
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A modular interface of IL-4 allows for scalable affinity without affecting specificity for the IL-4 receptor
Bmc Biol., 4, 2006
2B90
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BU of 2b90 by Molmil
Crystal structure of the interleukin-4 variant T13DR85A
分子名称: Interleukin-4, SULFATE ION
著者Kraich, M, Klein, M, Patino, E, Harrer, H, Sebald, W, Mueller, T.D.
登録日2005-10-10
公開日2006-05-30
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A modular interface of IL-4 allows for scalable affinity without affecting specificity for the IL-4 receptor
Bmc Biol., 4, 2006
2B8U
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BU of 2b8u by Molmil
Crystal structure of wildtype human Interleukin-4
分子名称: Interleukin-4, SULFATE ION
著者Kraich, M, Klein, M, Patino, E, Harrer, H, Sebald, W, Mueller, T.D.
登録日2005-10-10
公開日2006-05-30
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A modular interface of IL-4 allows for scalable affinity without affecting specificity for the IL-4 receptor
Bmc Biol., 4, 2006
2B8Y
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BU of 2b8y by Molmil
Crystal structure of the interleukin-4 variant T13DF82D
分子名称: Interleukin-4, SULFATE ION
著者Kraich, M, Klein, M, Patino, E, Harrer, H, Sebald, W, Mueller, T.D.
登録日2005-10-10
公開日2006-05-30
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A modular interface of IL-4 allows for scalable affinity without affecting specificity for the IL-4 receptor
Bmc Biol., 4, 2006
2B91
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BU of 2b91 by Molmil
Crystal structure of the interleukin-4 variant F82DR85A
分子名称: Interleukin-4, SULFATE ION
著者Kraich, M, Klein, M, Patino, E, Harrer, H, Sebald, W, Mueller, T.D.
登録日2005-10-10
公開日2006-05-30
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A modular interface of IL-4 allows for scalable affinity without affecting specificity for the IL-4 receptor
Bmc Biol., 4, 2006
2B8X
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BU of 2b8x by Molmil
Crystal structure of the interleukin-4 variant F82D
分子名称: Interleukin-4, SULFATE ION
著者Kraich, M, Klein, M, Patino, E, Harrer, H, Sebald, W, Mueller, T.D.
登録日2005-10-10
公開日2006-05-30
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A modular interface of IL-4 allows for scalable affinity without affecting specificity for the IL-4 receptor
Bmc Biol., 4, 2006
2D48
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BU of 2d48 by Molmil
Crystal structure of the Interleukin-4 variant T13D
分子名称: Interleukin-4, SULFATE ION
著者Kraich, M, Klein, M, Patino, E, Harrer, H, Sebald, W, Mueller, T.D.
登録日2005-10-11
公開日2006-05-30
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献A modular interface of IL-4 allows for scalable affinity without affecting specificity for the IL-4 receptor
Bmc Biol., 4, 2006
1ES7
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BU of 1es7 by Molmil
COMPLEX BETWEEN BMP-2 AND TWO BMP RECEPTOR IA ECTODOMAINS
分子名称: BONE MORPHOGENETIC PROTEIN RECEPTOR IA, BONE MORPHOGENETIC PROTEIN-2
著者Kirsch, T, Sebald, W, Dreyer, M.K.
登録日2000-04-07
公開日2000-10-07
最終更新日2018-04-04
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of the BMP-2-BRIA ectodomain complex.
Nat.Struct.Biol., 7, 2000
7O40
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BU of 7o40 by Molmil
Structural basis for VIPP1 oligomerization and maintenance of thylakoid membrane integrity
分子名称: ADENOSINE-5'-DIPHOSPHATE, Protein sll0617
著者Gupta, T.K, Klumpe, S, Gries, K, Strauss, M, Rudack, T, Schuller, J.M, Schroda, M, Engel, B.D.
登録日2021-04-03
公開日2021-06-30
最終更新日2021-07-21
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Structural basis for VIPP1 oligomerization and maintenance of thylakoid membrane integrity.
Cell, 184, 2021

 

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