1UPV
 
 | | Crystal structure of the human Liver X receptor beta ligand binding domain in complex with a synthetic agonist | | 分子名称: | N-(2,2,2-TRIFLUOROETHYL)-N-{4-[2,2,2-TRIFLUORO-1-HYDROXY-1-(TRIFLUOROMETHYL)ETHYL]PHENYL}BENZENESULFONAMIDE, OXYSTEROLS RECEPTOR LXR-BETA | | 著者 | Hoerer, S, Schmid, A, Heckel, A, Budzinski, R.M, Nar, H. | | 登録日 | 2003-10-13 | | 公開日 | 2004-10-20 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal Structure of the Human Liver X Receptor Beta Ligand-Binding Domain in Complex with a Synthetic Agonist
J.Mol.Biol., 334, 2003
|
|
1UPW
 | | Crystal structure of the human Liver X receptor beta ligand binding domain in complex with a synthetic agonist | | 分子名称: | N-(2,2,2-TRIFLUOROETHYL)-N-{4-[2,2,2-TRIFLUORO-1-HYDROXY-1-(TRIFLUOROMETHYL)ETHYL]PHENYL}BENZENESULFONAMIDE, OXYSTEROLS RECEPTOR LXR-BETA | | 著者 | Hoerer, S, Schmid, A, Heckel, A, Budzinski, R.M, Nar, H. | | 登録日 | 2003-10-13 | | 公開日 | 2004-10-20 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal Structure of the Human Liver X Receptor Beta Ligand-Binding Domain in Complex with a Synthetic Agonist
J.Mol.Biol., 334, 2003
|
|
1URI
 | | AZURIN MUTANT WITH MET 121 REPLACED BY GLN | | 分子名称: | AZURIN, COPPER (II) ION, SULFATE ION | | 著者 | Romero, A, Nar, H, Huber, R, Messerschmidt, A. | | 登録日 | 1996-11-14 | | 公開日 | 1997-04-01 | | 最終更新日 | 2018-04-18 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | X-ray analysis and spectroscopic characterization of M121Q azurin. A copper site model for stellacyanin.
J.Mol.Biol., 229, 1993
|
|
6SVL
 | |
6ZLE
 | |
7ACC
 | |
6ZPR
 | | Solution structure of MLKL executioner domain in complex with a covalent inhibitor | | 分子名称: | 7-(2-methoxyethoxymethyl)-1,3-dimethyl-purine-2,6-dione, Mixed lineage kinase domain-like protein,Mixed lineage kinase domain-like protein | | 著者 | Ruebbelke, M, Bauer, M, Hamilton, J, Binder, F, Nar, H, Zeeb, M. | | 登録日 | 2020-07-09 | | 公開日 | 2020-12-16 | | 最終更新日 | 2021-01-06 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Locking mixed-lineage kinase domain-like protein in its auto-inhibited state prevents necroptosis.
Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
6ZVO
 | |
6ZZ1
 | | Crystal structure of MLKL executioner domain in complex with a covalent inhibitor | | 分子名称: | 7-(2-methoxyethoxymethyl)-1,3-dimethyl-purine-2,6-dione, Mixed lineage kinase domain-like protein | | 著者 | Fiegen, D, Bauer, M, Nar, H. | | 登録日 | 2020-08-03 | | 公開日 | 2020-12-23 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | | 主引用文献 | Locking mixed-lineage kinase domain-like protein in its auto-inhibited state prevents necroptosis.
Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
7ALC
 | | human GCH-GFRP stimulatory complex | | 分子名称: | GTP cyclohydrolase 1, GTP cyclohydrolase 1 feedback regulatory protein, PHENYLALANINE, ... | | 著者 | Ebenhoch, R, Nar, H. | | 登録日 | 2020-10-06 | | 公開日 | 2021-10-13 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.726 Å) | | 主引用文献 | A hybrid approach reveals the allosteric regulation of GTP cyclohydrolase I.
Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
7AL9
 | |
7ALA
 | | human GCH-GFRP inhibitory complex | | 分子名称: | 2-azanyl-8-[(4-fluorophenyl)methylsulfanyl]-1,7-dihydropurin-6-one, GTP cyclohydrolase 1, GTP cyclohydrolase 1 feedback regulatory protein, ... | | 著者 | Ebenhoch, R, Nar, H. | | 登録日 | 2020-10-06 | | 公開日 | 2021-10-13 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.846 Å) | | 主引用文献 | A hybrid approach reveals the allosteric regulation of GTP cyclohydrolase I.
Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
7ALB
 | | human GCH-GFRP stimulatory complex 7-deaza-GTP bound | | 分子名称: | 7-deaza-GTP, GTP cyclohydrolase 1, GTP cyclohydrolase 1 feedback regulatory protein, ... | | 著者 | Ebenhoch, R, Nar, H. | | 登録日 | 2020-10-06 | | 公開日 | 2021-10-13 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.979 Å) | | 主引用文献 | A hybrid approach reveals the allosteric regulation of GTP cyclohydrolase I.
Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
7ALQ
 | | human GCH-GFRP inhibitory complex 7-deaza-GTP bound | | 分子名称: | 7,8-DIHYDROBIOPTERIN, 7-deaza-GTP, GTP cyclohydrolase 1, ... | | 著者 | Ebenhoch, R, Nar, H. | | 登録日 | 2020-10-07 | | 公開日 | 2021-10-20 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.205 Å) | | 主引用文献 | Biophysical and structural investigation of the regulation of human GTP cyclohydrolase I by its regulatory protein GFRP.
J.Struct.Biol., 213, 2021
|
|
4JN1
 | | An Antidote for Dabigatran | | 分子名称: | GLYCEROL, anti-dabigatran Fab1, heavy chain, ... | | 著者 | Schiele, F, Nar, H. | | 登録日 | 2013-03-14 | | 公開日 | 2013-03-27 | | 最終更新日 | 2013-07-24 | | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | | 主引用文献 | A specific antidote for dabigatran: functional and structural characterization.
Blood, 121, 2013
|
|
4JN2
 | | An Antidote for Dabigatran | | 分子名称: | GLYCEROL, N-[(2-{[(4-carbamimidoylphenyl)amino]methyl}-1-methyl-1H-benzimidazol-5-yl)carbonyl]-N-pyridin-2-yl-beta-alanine, anti dabigatran Fab | | 著者 | Schiele, F, Nar, H. | | 登録日 | 2013-03-14 | | 公開日 | 2013-03-27 | | 最終更新日 | 2015-03-11 | | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | | 主引用文献 | A specific antidote for dabigatran: functional and structural characterization.
Blood, 121, 2013
|
|
4K8R
 | |
4LKC
 | |
3ZGC
 | | crystal structure of the KEAP1-NEH2 complex | | 分子名称: | ACETATE ION, KELCH-LIKE ECH-ASSOCIATED PROTEIN 1, NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR 2 | | 著者 | Hoerer, S, Reinert, D, Ostmann, K, Hoevels, Y, Nar, H. | | 登録日 | 2012-12-17 | | 公開日 | 2013-06-12 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal-Contact Engineering to Obtain a Crystal Form of the Kelch Domain of Human Keap1 Suitable for Ligand-Soaking Experiments.
Acta Crystallogr.,Sect.F, 69, 2013
|
|
3ZGD
 | | crystal structure of a KEAP1 mutant | | 分子名称: | ACETATE ION, KELCH-LIKE ECH-ASSOCIATED PROTEIN 1, SODIUM ION | | 著者 | Hoerer, S, Reinert, D, Ostmann, K, Hoevels, Y, Nar, H. | | 登録日 | 2012-12-17 | | 公開日 | 2013-06-12 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Crystal-Contact Engineering to Obtain a Crystal Form of the Kelch Domain of Human Keap1 Suitable for Ligand-Soaking Experiments.
Acta Crystallogr.,Sect.F, 69, 2013
|
|
4BB9
 | | Crystal structure of glucokinase regulatory protein complexed to fructose-1-phosphate | | 分子名称: | 1-O-phosphono-beta-D-fructopyranose, CALCIUM ION, GLUCOKINASE REGULATORY PROTEIN | | 著者 | Pautsch, A, Stadler, N, Loehle, A, Lenter, M, Rist, W, Berg, A, Glocker, L, Nar, H, Reinert, D, Heckel, A, Schnapp, G, Kauschke, S.G. | | 登録日 | 2012-09-21 | | 公開日 | 2013-05-15 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | | 主引用文献 | Crystal Structure of Glucokinase Regulatory Protein.
Biochemistry, 52, 2013
|
|
4BBA
 | | Crystal structure of glucokinase regulatory protein complexed to phosphate | | 分子名称: | GLUCOKINASE REGULATORY PROTEIN, PHOSPHATE ION | | 著者 | Pautsch, A, Stadler, N, Loehle, A, Lenter, M, Rist, W, Berg, A, Glocker, L, Nar, H, Reinhart, D, Heckel, A, Schnapp, G, Kauschke, S.G. | | 登録日 | 2012-09-21 | | 公開日 | 2013-05-15 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Crystal Structure of Glucokinase Regulatory Protein.
Biochemistry, 52, 2013
|
|
1OAA
 | | MOUSE SEPIAPTERIN REDUCTASE COMPLEXED WITH NADP AND OXALOACETATE | | 分子名称: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, OXALOACETATE ION, SEPIAPTERIN REDUCTASE, ... | | 著者 | Auerbach, G, Herrmann, A, Bacher, A, Huber, R. | | 登録日 | 1997-08-25 | | 公開日 | 1999-02-16 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | The 1.25 A crystal structure of sepiapterin reductase reveals its binding mode to pterins and brain neurotransmitters.
EMBO J., 16, 1997
|
|
8OMG
 | | Crystal structure of mKHK (apo) | | 分子名称: | Ketohexokinase | | 著者 | Ebenhoch, E, Pautsch, P. | | 登録日 | 2023-03-31 | | 公開日 | 2023-09-27 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Crystal structures of human and mouse ketohexokinase provide a structural basis for species- and isoform-selective inhibitor design.
Acta Crystallogr D Struct Biol, 79, 2023
|
|
8OMF
 | |
