6ZVO
Crystal structure of unliganded MLKL executioner domain
Summary for 6ZVO
| Entry DOI | 10.2210/pdb6zvo/pdb |
| Related | 6zle 6zpr |
| Descriptor | Mixed lineage kinase domain-like protein, CHLORIDE ION, BROMIDE ION, ... (4 entities in total) |
| Functional Keywords | necroptosis, lipid binding protein |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 3 |
| Total formula weight | 53113.24 |
| Authors | Fiegen, D.,Bauer, M.,Nar, H. (deposition date: 2020-07-27, release date: 2020-12-23, Last modification date: 2024-01-31) |
| Primary citation | Rubbelke, M.,Fiegen, D.,Bauer, M.,Binder, F.,Hamilton, J.,King, J.,Thamm, S.,Nar, H.,Zeeb, M. Locking mixed-lineage kinase domain-like protein in its auto-inhibited state prevents necroptosis. Proc.Natl.Acad.Sci.USA, 117:33272-33281, 2020 Cited by PubMed: 33318170DOI: 10.1073/pnas.2017406117 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.371 Å) |
Structure validation
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