3TRW
 
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4RWC
 | | Racemic M2-TM crystallized from racemic detergent | | 分子名称: | Matrix protein 2, octyl beta-D-glucopyranoside | | 著者 | Mortenson, D.E, Steinkruger, J.D, Kreitler, D.F, Gellman, S.H, Forest, K.T. | | 登録日 | 2014-12-02 | | 公開日 | 2015-10-14 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | | 主引用文献 | High-resolution structures of a heterochiral coiled coil.
Proc.Natl.Acad.Sci.USA, 112, 2015
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5VTJ
 | | Structure of Pin1 WW Domain Sequence 1 Substituted with [S,S]ACPC | | 分子名称: | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, SULFATE ION | | 著者 | Mortenson, D.E, Kreitler, D.F, Thomas, N.C, Gellman, S.H, Forest, K.T. | | 登録日 | 2017-05-17 | | 公開日 | 2018-02-21 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Evaluation of beta-Amino Acid Replacements in Protein Loops: Effects on Conformational Stability and Structure.
Chembiochem, 19, 2018
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5VTK
 | | Structure of Pin1 WW Domain Variant 1 with beta3-Ser Loop Substitution | | 分子名称: | CHLORIDE ION, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | | 著者 | Mortenson, D.E, Kreitler, D.F, Thomas, N.C, Gellman, S.H, Forest, K.T. | | 登録日 | 2017-05-17 | | 公開日 | 2018-02-21 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Evaluation of beta-Amino Acid Replacements in Protein Loops: Effects on Conformational Stability and Structure.
Chembiochem, 19, 2018
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5VTI
 | | Structure of Pin1 WW Domain Sequence 3 with [R,R]-ACPC Loop Substitution | | 分子名称: | CHLORIDE ION, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | | 著者 | Mortenson, D.E, Kreitler, D.F, Thomas, N.C, Gellman, S.H, Forest, K.T. | | 登録日 | 2017-05-17 | | 公開日 | 2018-02-21 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Evaluation of beta-Amino Acid Replacements in Protein Loops: Effects on Conformational Stability and Structure.
Chembiochem, 19, 2018
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4RWB
 | | Racemic influenza M2-TM crystallized from monoolein lipidic cubic phase | | 分子名称: | Matrix protein 2, [(Z)-octadec-9-enyl] (2R)-2,3-bis(oxidanyl)propanoate | | 著者 | Mortenson, D.E, Steinkruger, J.D, Kreitler, D.F, Gellman, S.H, Forest, K.T. | | 登録日 | 2014-12-02 | | 公開日 | 2015-10-14 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | High-resolution structures of a heterochiral coiled coil.
Proc.Natl.Acad.Sci.USA, 112, 2015
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3TJW
 | | Crystal Structure of Quasiracemic Villin Headpiece Subdomain Containing (F5Phe10) Substitution | | 分子名称: | D-Villin-1, L-Villin-1, SULFATE ION | | 著者 | Mortenson, D.E, Satyshur, K.A, Gellman, S.H, Forest, K.T. | | 登録日 | 2011-08-25 | | 公開日 | 2012-01-25 | | 最終更新日 | 2017-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | | 主引用文献 | Quasiracemic crystallization as a tool to assess the accommodation of noncanonical residues in nativelike protein conformations.
J.Am.Chem.Soc., 134, 2012
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3TRV
 | | Crystal structure of quasiracemic villin headpiece subdomain containing (F5Phe17) substitution | | 分子名称: | D-Villin-1, ISOPROPYL ALCOHOL, L-Villin-1, ... | | 著者 | Mortenson, D.E, Satyshur, K.A, Gellman, S.H, Forest, K.T. | | 登録日 | 2011-09-11 | | 公開日 | 2012-01-25 | | 最終更新日 | 2017-11-08 | | 実験手法 | X-RAY DIFFRACTION (1 Å) | | 主引用文献 | Quasiracemic crystallization as a tool to assess the accommodation of noncanonical residues in nativelike protein conformations.
J.Am.Chem.Soc., 134, 2012
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3TRY
 | | Crystal structure of racemic villin headpiece subdomain in space group I-4c2 | | 分子名称: | D-Villin-1, SULFATE ION | | 著者 | Mortenson, D.E, Satyshur, K.A, Gellman, S.H, Forest, K.T. | | 登録日 | 2011-09-11 | | 公開日 | 2012-01-25 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Quasiracemic crystallization as a tool to assess the accommodation of noncanonical residues in nativelike protein conformations.
J.Am.Chem.Soc., 134, 2012
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5UEH
 | | Structure of GSTO1 covalently conjugated to quinolinic acid fluorosulfate | | 分子名称: | 2-(4-chlorophenyl)-6-[(fluorosulfonyl)oxy]quinoline-4-carboxylic acid, GLYCEROL, Glutathione S-transferase omega-1, ... | | 著者 | Mortenson, D.E, Wilson, I.A, Kelly, J.W. | | 登録日 | 2017-01-02 | | 公開日 | 2018-01-17 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | "Inverse Drug Discovery" Strategy To Identify Proteins That Are Targeted by Latent Electrophiles As Exemplified by Aryl Fluorosulfates.
J. Am. Chem. Soc., 140, 2018
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5UI4
 | | Structure of NME1 covalently conjugated to imidazole fluorosulfate | | 分子名称: | 4-[4-(3-methoxyphenyl)-1-(prop-2-yn-1-yl)-1H-imidazol-5-yl]phenyl sulfurofluoridate, Nucleoside diphosphate kinase A | | 著者 | Mortenson, D.E, Brighty, G.J, Wilson, I.A, Kelly, J.W. | | 登録日 | 2017-01-12 | | 公開日 | 2018-01-17 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | "Inverse Drug Discovery" Strategy To Identify Proteins That Are Targeted by Latent Electrophiles As Exemplified by Aryl Fluorosulfates.
J. Am. Chem. Soc., 140, 2018
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4GWV
 | | Structure of racemic Pin1 WW domain cocrystallized with tri-ammonium citrate | | 分子名称: | CITRATE ANION, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | | 著者 | Mortenson, D.E, Yun, H.G, Gellman, S.H, Forest, K.T. | | 登録日 | 2012-09-03 | | 公開日 | 2013-10-16 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | Evidence for small-molecule-mediated loop stabilization in the structure of the isolated Pin1 WW domain.
Acta Crystallogr.,Sect.D, 69, 2013
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4GWT
 | | Structure of racemic Pin1 WW domain cocrystallized with DL-malic acid | | 分子名称: | (2S)-2-hydroxybutanedioic acid, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | | 著者 | Mortenson, D.E, Yun, H.G, Gellman, S.H, Forest, K.T. | | 登録日 | 2012-09-03 | | 公開日 | 2013-10-16 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Evidence for small-molecule-mediated loop stabilization in the structure of the isolated Pin1 WW domain.
Acta Crystallogr.,Sect.D, 69, 2013
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7THA
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4MGP
 | | Structure of racemic Ala-(8,13,18) Magainin 2 | | 分子名称: | Magainin 2 Derivative | | 著者 | Hayouka, Z, Mortenson, D.E, Kreitler, D.F, Weisblum, B, Gellman, S.H, Forest, K.T. | | 登録日 | 2013-08-28 | | 公開日 | 2013-10-16 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Evidence for Phenylalanine Zipper-Mediated Dimerization in the X-ray Crystal Structure of a Magainin 2 Analogue.
J.Am.Chem.Soc., 135, 2013
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5TZL
 | | Structure of transthyretin in complex with the kinetic stabilizer 201 | | 分子名称: | 4-(7-chloro-1,3-benzoxazol-2-yl)-2,6-diiodophenol, Transthyretin | | 著者 | Connelly, S, Mortenson, D.E, Choi, S, Wilson, I.A, Powers, E.T, Kelly, J.W, Johnson, S.M. | | 登録日 | 2016-11-21 | | 公開日 | 2017-06-28 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Semi-quantitative models for identifying potent and selective transthyretin amyloidogenesis inhibitors.
Bioorg. Med. Chem. Lett., 27, 2017
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6MG5
 | | Structure of full-length human lambda-6A light chain JTO in complex with coumarin 1 | | 分子名称: | 7-(diethylamino)-4-methyl-2H-1-benzopyran-2-one, Light chain JTO, PHOSPHATE ION | | 著者 | Morgan, G.J, Yan, N.L, Mortenson, D.E, Stanfield, R.L, Wilson, I.A, Kelly, J.W. | | 登録日 | 2018-09-12 | | 公開日 | 2019-04-10 | | 最終更新日 | 2019-12-25 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Stabilization of amyloidogenic immunoglobulin light chains by small molecules.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6MPL
 | | Racemic M2-TM I39A crystallized from racemic detergent | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Matrix protein 2, octyl beta-D-glucopyranoside | | 著者 | Kreitler, D.F, Yao, Z, Mortenson, D.E, Forest, K.T, Gellman, S.H. | | 登録日 | 2018-10-07 | | 公開日 | 2019-01-30 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | A Hendecad Motif Is Preferred for Heterochiral Coiled-Coil Formation.
J. Am. Chem. Soc., 141, 2019
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6MPN
 | | Racemic M2-TM I42E crystallized from racemic detergent | | 分子名称: | Matrix protein 2, octyl beta-D-glucopyranoside | | 著者 | Kreitler, D.F, Yao, Z, Mortenson, D.E, Forest, K.T, Gellman, S.H. | | 登録日 | 2018-10-07 | | 公開日 | 2019-01-30 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | A Hendecad Motif Is Preferred for Heterochiral Coiled-Coil Formation.
J. Am. Chem. Soc., 141, 2019
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6MPM
 | | Racemic M2-TM I42A crystallized from racemic detergent | | 分子名称: | Matrix protein 2, octyl beta-D-glucopyranoside | | 著者 | Kreitler, D.F, Yao, Z, Mortenson, D.E, Forest, K.T, Gellman, S.H. | | 登録日 | 2018-10-07 | | 公開日 | 2019-01-30 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | A Hendecad Motif Is Preferred for Heterochiral Coiled-Coil Formation.
J. Am. Chem. Soc., 141, 2019
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6MG4
 | | Structure of full-length human lambda-6A light chain JTO | | 分子名称: | JTO light chain | | 著者 | Morgan, G.J, Yan, N.L, Mortenson, D.E, Stanfield, R.L, Wilson, I.A, Kelly, J.W. | | 登録日 | 2018-09-12 | | 公開日 | 2019-04-10 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Stabilization of amyloidogenic immunoglobulin light chains by small molecules.
Proc.Natl.Acad.Sci.USA, 116, 2019
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5I1P
 | | Villin headpiece subdomain with a Lys30 to beta-3-homolysine substitution | | 分子名称: | D-Villin headpiece subdomain, ETHANOL, Villin-1 | | 著者 | Kreitler, D.F, Mortenson, D.E, Gellman, S.H, Forest, K.T. | | 登録日 | 2016-02-05 | | 公開日 | 2016-05-25 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Effects of Single alpha-to-beta Residue Replacements on Structure and Stability in a Small Protein: Insights from Quasiracemic Crystallization.
J.Am.Chem.Soc., 138, 2016
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5I1O
 | | Villin headpiece subdomain with a Gln26 to ACPC substitution | | 分子名称: | D-Villin headpiece subdomain, Villin-1 | | 著者 | Kreitler, D.F, Mortenson, D.E, Gellman, S.H, Forest, K.T. | | 登録日 | 2016-02-05 | | 公開日 | 2016-05-25 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.348 Å) | | 主引用文献 | Effects of Single alpha-to-beta Residue Replacements on Structure and Stability in a Small Protein: Insights from Quasiracemic Crystallization.
J.Am.Chem.Soc., 138, 2016
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5I1S
 | | Villin headpiece subdomain with a Lys30 to APC substitution | | 分子名称: | D-Villin headpiece subdomain, Villin-1 | | 著者 | Kreitler, D.F, Mortenson, D.E, Gellman, S.H, Forest, K.T. | | 登録日 | 2016-02-05 | | 公開日 | 2016-05-25 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.12 Å) | | 主引用文献 | Effects of Single alpha-to-beta Residue Replacements on Structure and Stability in a Small Protein: Insights from Quasiracemic Crystallization.
J.Am.Chem.Soc., 138, 2016
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4HJD
 | | GCN4pLI derivative with alpha/beta/acyclic-gamma amino acid substitution pattern | | 分子名称: | GCN4pLI(alpha/beta/acyclic gamma) | | 著者 | Shin, Y.H, Mortenson, D.E, Satyshur, K.A, Forest, K.T, Gellman, S.H. | | 登録日 | 2012-10-12 | | 公開日 | 2013-06-12 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Differential Impact of beta and gamma Residue Preorganization on alpha / beta / gamma-Peptide Helix Stability in Water.
J.Am.Chem.Soc., 135, 2013
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