5TZL
Structure of transthyretin in complex with the kinetic stabilizer 201
Summary for 5TZL
| Entry DOI | 10.2210/pdb5tzl/pdb |
| Descriptor | Transthyretin, 4-(7-chloro-1,3-benzoxazol-2-yl)-2,6-diiodophenol (3 entities in total) |
| Functional Keywords | transthyretin, kinetic stabilizer, transport protein |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 2 |
| Total formula weight | 28645.63 |
| Authors | Connelly, S.,Mortenson, D.E.,Choi, S.,Wilson, I.A.,Powers, E.T.,Kelly, J.W.,Johnson, S.M. (deposition date: 2016-11-21, release date: 2017-06-28, Last modification date: 2023-11-15) |
| Primary citation | Connelly, S.,Mortenson, D.E.,Choi, S.,Wilson, I.A.,Powers, E.T.,Kelly, J.W.,Johnson, S.M. Semi-quantitative models for identifying potent and selective transthyretin amyloidogenesis inhibitors. Bioorg. Med. Chem. Lett., 27:3441-3449, 2017 Cited by PubMed: 28625364DOI: 10.1016/j.bmcl.2017.05.080 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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