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2HIN
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BU of 2hin by Molmil
Structure of N15 Cro at 1.05 A: an ortholog of lambda Cro with a completely different but equally effective dimerization mechanism
Descriptor: Repressor protein, SULFATE ION
Authors:Dubrava, M.S, Ingram, W.M, Roberts, S.A, Weichsel, A, Montfort, W.R, Cordes, M.H.
Deposit date:2006-06-29
Release date:2007-07-10
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:N15 Cro and lambda Cro: orthologous DNA-binding domains with completely different but equally effective homodimer interfaces.
Protein Sci., 17, 2008
2ACP
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BU of 2acp by Molmil
Crystal structure of nitrophorin 2 aqua complex
Descriptor: Nitrophorin 2, PROTOPORPHYRIN IX CONTAINING FE
Authors:Weichsel, A, Berry, R.E, Walker, F.A, Montfort, W.R.
Deposit date:2005-07-19
Release date:2006-06-27
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structures, ligand induced conformational change and heme deformation in complexes of nitrophorin 2, a nitric oxide transport protein from rhodnius prolixus
To be Published
2A3F
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BU of 2a3f by Molmil
Crystal structure of nitrophorin 2 aqua complex
Descriptor: Nitrophorin 2, PROTOPORPHYRIN IX CONTAINING FE
Authors:Weichsel, A, Berry, R.E, Walker, F.A, Montfort, W.R.
Deposit date:2005-06-24
Release date:2006-06-06
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structures, ligand induced conformational change and heme deformation in complexes of nitrophorin 2, a nitric oxide transport protein from rhodnius prolixus.
To be Published
2AL0
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BU of 2al0 by Molmil
Crystal structure of nitrophorin 2 ferrous aqua complex
Descriptor: CITRIC ACID, Nitrophorin 2, PROTOPORPHYRIN IX CONTAINING FE
Authors:Weichsel, A, Berry, R.E, Walker, F.A, Montfort, W.R.
Deposit date:2005-08-04
Release date:2006-07-18
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structures, ligand induced conformational change and heme deformation in complexes of nitrophorin 2, a nitric oxide transport protein from rhodnius prolixus
To be Published
2NRM
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BU of 2nrm by Molmil
S-nitrosylated blackfin tuna myoglobin
Descriptor: GLYCEROL, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE
Authors:Schreiter, E.R, Rodr guez, M.M, Weichsel, A, Montfort, W.R, Bonaventura, J.
Deposit date:2006-11-02
Release date:2007-05-08
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.09 Å)
Cite:S-nitrosylation-induced conformational change in blackfin tuna myoglobin.
J.Biol.Chem., 282, 2007
2NRL
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BU of 2nrl by Molmil
Blackfin tuna myoglobin
Descriptor: 1,2-ETHANEDIOL, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE
Authors:Schreiter, E.R, Rodr guez, M.M, Weichsel, A, Montfort, W.R, Bonaventura, J.
Deposit date:2006-11-02
Release date:2007-05-08
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (0.91 Å)
Cite:S-nitrosylation-induced conformational change in blackfin tuna myoglobin.
J.Biol.Chem., 282, 2007
2AH7
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BU of 2ah7 by Molmil
Crystal structure of nitrophorin 2 aqua complex
Descriptor: Nitrophorin 2, PROTOPORPHYRIN IX CONTAINING FE
Authors:Weichsel, A, Berry, R.E, Walker, F.A, Montfort, W.R.
Deposit date:2005-07-27
Release date:2006-07-18
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structures, ligand induced conformational change and heme deformation in complexes of nitrophorin 2, a nitric oxide transport protein from rhodnius prolixus
To be Published
2ASN
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BU of 2asn by Molmil
Crystal structure of D1A mutant of nitrophorin 2 complexed with imidazole
Descriptor: IMIDAZOLE, Nitrophorin 2, PROTOPORPHYRIN IX CONTAINING FE
Authors:Weichsel, A, Berry, R.E, Walker, F.A, Montfort, W.R.
Deposit date:2005-08-23
Release date:2006-08-01
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structures, ligand induced conformational change and heme deformation in complexes of nitrophorin 2, a nitric oxide transport protein from rhodnius prolixus
To be Published
2AMM
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BU of 2amm by Molmil
Crystal structure of L122V/L132V mutant of nitrophorin 2
Descriptor: Nitrophorin 2, PROTOPORPHYRIN IX CONTAINING FE
Authors:Weichsel, A, Berry, R.E, Walker, F.A, Montfort, W.R.
Deposit date:2005-08-09
Release date:2006-07-18
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structures, ligand induced conformational change and heme deformation in complexes of nitrophorin 2, a nitric oxide transport protein from rhodnius prolixus
To be Published
2ALL
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BU of 2all by Molmil
Crystal structure of L122V/L132V mutant of nitrophorin 2
Descriptor: Nitrophorin 2, PROTOPORPHYRIN IX CONTAINING FE
Authors:Weichsel, A, Berry, R.E, Walker, F.A, Montfort, W.R.
Deposit date:2005-08-05
Release date:2006-07-18
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Crystal structures, ligand induced conformational change and heme deformation in complexes of nitrophorin 2, a nitric oxide transport protein from rhodnius prolixus
To be Published
2NX0
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BU of 2nx0 by Molmil
Ferrous nitrosyl blackfin tuna myoglobin
Descriptor: Myoglobin, NITRIC OXIDE, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Schreiter, E.R, Rodriguez, M.M, Weichsel, A, Montfort, W.R, Bonaventura, J.
Deposit date:2006-11-16
Release date:2007-05-08
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (0.95 Å)
Cite:S-nitrosylation-induced conformational change in blackfin tuna myoglobin.
J.Biol.Chem., 282, 2007
2PIJ
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BU of 2pij by Molmil
Structure of the Cro protein from prophage Pfl 6 in Pseudomonas fluorescens Pf-5
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, BICARBONATE ION, Prophage Pfl 6 Cro, ...
Authors:Roessler, C.G, Roberts, S.A, Montfort, W.R, Cordes, M.H.J.
Deposit date:2007-04-13
Release date:2008-03-04
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Transitive homology-guided structural studies lead to discovery of Cro proteins with 40% sequence identity but different folds.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2TSR
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BU of 2tsr by Molmil
THYMIDYLATE SYNTHASE FROM RAT IN TERNARY COMPLEX WITH DUMP AND TOMUDEX
Descriptor: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE, TOMUDEX
Authors:Sotelo-Mundo, R.R, Ciesla, J, Dzik, J.M, Rode, W, Maley, F, Maley, G, Hardy, L.W, Montfort, W.R.
Deposit date:1998-06-19
Release date:1999-02-16
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structures of rat thymidylate synthase inhibited by Tomudex, a potent anticancer drug.
Biochemistry, 38, 1999
1NP1
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BU of 1np1 by Molmil
CRYSTAL STRUCTURE OF THE COMPLEX OF NITROPHORIN 1 FROM RHODNIUS PROLIXUS WITH HISTAMINE
Descriptor: HISTAMINE, NITROPHORIN 1, PHOSPHATE ION, ...
Authors:Weichsel, A, Montfort, W.R.
Deposit date:1998-01-19
Release date:1998-05-27
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of a nitric oxide transport protein from a blood-sucking insect.
Nat.Struct.Biol., 5, 1998
1T68
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BU of 1t68 by Molmil
Crystal structure of nitrophorin 2 complex with NO
Descriptor: NITRIC OXIDE, Nitrophorin 2, PROTOPORPHYRIN IX CONTAINING FE
Authors:Weichsel, A, Montfort, W.R.
Deposit date:2004-05-05
Release date:2005-05-17
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Conformational change and heme ruffling in nitrophorin 2, a nitric oxide carrier from kissing bug
To be Published
3BBF
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BU of 3bbf by Molmil
Crystal structure of the NM23-H2 transcription factor complex with GDP
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Weichsel, A, Montfort, W.R.
Deposit date:2007-11-09
Release date:2008-09-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:NM23-H2 may play an indirect role in transcriptional activation of c-myc gene expression but does not cleave the nuclease hypersensitive element III1.
Mol.Cancer Ther., 8, 2009
1NTF
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BU of 1ntf by Molmil
Crystal Structure of Cimex Nitrophorin
Descriptor: PROTOPORPHYRIN IX CONTAINING FE, salivary nitrophorin
Authors:Weichsel, A, Maes, E.M, Andersen, J.F, Valenzuela, J.G, Walker, F.A, Montfort, W.R.
Deposit date:2003-01-29
Release date:2004-03-16
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Heme-assisted S-nitrosation of a proximal thiolate in a nitric oxide transport protein.
Proc.Natl.Acad.Sci.USA, 102, 2005
1TSD
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BU of 1tsd by Molmil
THYMIDYLATE SYNTHASE COMPLEX WITH 2'-DEOXYURIDINE 5'-MONOPHOSPHATE (DUMP) AND FOLATE ANALOG 1843U89
Descriptor: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, BETA-MERCAPTOETHANOL, S)-2-(5(((1,2-DIHYDRO-3-METHYL-1-OXOBENZO(F)QUINAZOLIN-9-YL)METHYL)AMINO)1-OXO-2-ISOINDOLINYL)GLUTARIC ACID, ...
Authors:Weichsel, A, Montfort, W.R.
Deposit date:1995-08-15
Release date:1996-01-29
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Ligand-induced distortion of an active site in thymidylate synthase upon binding anticancer drug 1843U89.
Nat.Struct.Biol., 2, 1995
3B9H
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BU of 3b9h by Molmil
E. coli thymidylate synthase complexed with 5-NITRO-2'-DEOXY URIDINE
Descriptor: 2'-DEOXY-5-NITROURIDINE 5'-MONOPHOSPHATE, PHOSPHATE ION, Thymidylate synthase
Authors:Roberts, S.A, Montfort, W.R.
Deposit date:2007-11-05
Release date:2008-11-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Structural Studies of Early Events in the Thymidylate Synthase Reaction
To be Published
3BD1
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BU of 3bd1 by Molmil
Structure of the Cro protein from putative prophage element Xfaso 1 in Xylella fastidiosa strain Ann-1
Descriptor: CHLORIDE ION, Cro protein, GLYCEROL, ...
Authors:Hall, B.M, Roberts, S.A, Montfort, W.R, Cordes, M.H.
Deposit date:2007-11-13
Release date:2008-03-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Transitive homology-guided structural studies lead to discovery of Cro proteins with 40% sequence identity but different folds
Proc.Natl.Acad.Sci.Usa, 105, 2008
3BBB
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BU of 3bbb by Molmil
Crystal structure of the NM23-H2 transcription factor complex with dinucleotide d(AG)
Descriptor: 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, Nucleoside diphosphate kinase B
Authors:Weichsel, A, Montfort, W.R.
Deposit date:2007-11-09
Release date:2008-09-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:NM23-H2 may play an indirect role in transcriptional activation of c-myc gene expression but does not cleave the nuclease hypersensitive element III1.
Mol.Cancer Ther., 8, 2009
3BHR
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BU of 3bhr by Molmil
E. coli TS complexed with 5-NO2dUMP and tetrahydrofolate at 1.9 A resolution (space group 152)
Descriptor: (6S)-5,6,7,8-TETRAHYDROFOLATE, 2'-DEOXY-5-NITROURIDINE 5'-MONOPHOSPHATE, PHOSPHATE ION, ...
Authors:Roberts, S.A, Montfort, W.R.
Deposit date:2007-11-28
Release date:2008-12-02
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Studies of Early Events in Catalysis by Thymidylate Synthase
To be Published
3BFI
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BU of 3bfi by Molmil
E. Coli Thymidylate Synthase Y209M mutant complexed with 5-nitro-dUMP
Descriptor: 2'-DEOXY-5-NITROURIDINE 5'-MONOPHOSPHATE, SULFATE ION, Thymidylate synthase
Authors:Roberts, S.A, Montfort, W.R.
Deposit date:2007-11-21
Release date:2008-12-02
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:E.Coli thymidylate synthase complexed with 5-NITRO-2'-DEOXY URIDINE
To be Published
1U0X
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BU of 1u0x by Molmil
Crystal structure of nitrophorin 4 under pressure of xenon (200 psi)
Descriptor: AMMONIA, Nitrophorin 4, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Nienhaus, K, Maes, E.M, Weichsel, A, Montfort, W.R, Nienhaus, G.U.
Deposit date:2004-07-14
Release date:2004-07-20
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structural dynamics controls nitric oxide affinity in nitrophorin 4
J.Biol.Chem., 279, 2004
3BHL
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BU of 3bhl by Molmil
E.coli thymidylate synthase complexes with 5-NO2dUMP and tetrahydrofolate at 1.4 A resolution
Descriptor: (6S)-5,6,7,8-TETRAHYDROFOLATE, 2'-DEOXY-5-NITROURIDINE 5'-MONOPHOSPHATE, SULFATE ION, ...
Authors:Roberts, S.A, Montfort, W.R.
Deposit date:2007-11-28
Release date:2008-12-02
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural Studies of Early Events in Catalysis by Thymidylate Synthase
To be Published

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