3BHL

E.coli thymidylate synthase complexes with 5-NO2dUMP and tetrahydrofolate at 1.4 A resolution

Summary for 3BHL

• Entry DOI: 10.2210/pdb3bhl/pdb
• Related: 3B9H 3BFI 3BGX 3BHR
• Descriptor: Thymidylate synthase, 2'-DEOXY-5-NITROURIDINE 5'-MONOPHOSPHATE, (6S)-5,6,7,8-TETRAHYDROFOLATE, ... (5 entities in total)
• Functional Keywords: methyltransferase, nucleotide biosynthesis, repressor, rna-binding, translation regulation, transferase
• Biological source: Escherichia coli
• Cellular location: Cytoplasm: P0A884
• Total number of polymer chains: 2
• Total formula weight: 63008.77

Authors

Roberts, S.A.,Montfort, W.R. (deposition date: 2007-11-28, release date: 2008-12-02, Last modification date: 2023-08-30)

• Primary citation: Arendall III, W.B.,Hyatt, D.C.,Roberts, S.A.,Weichsel, A.,Dahlgren, A.L.,Maley, F.,Montfort, W.R.; Structural Studies of Early Events in Catalysis by Thymidylate Synthase; To be Published,

Experimental method

X-RAY DIFFRACTION (1.4 Å)