3BHL

E.coli thymidylate synthase complexes with 5-NO2dUMP and tetrahydrofolate at 1.4 A resolution

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Thymidylate synthase	polymer	264	30559.7	2	UniProt (P0A884) Pfam (PF00303)	Escherichia coli	TS, TSase
2	C, G (A, B)	2'-DEOXY-5-NITROURIDINE 5'-MONOPHOSPHATE	non-polymer		355.2	2	Chemie (NDU)
3	D, H (A, B)	(6S)-5,6,7,8-TETRAHYDROFOLATE	non-polymer		445.4	2	Chemie (THG)
4	E, F, I (A, B)	SULFATE ION	non-polymer		96.1	3	Chemie (SO4)
5	J, K (A, B)	water	water		18.0	437	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	61119.3
Non-Polymers*	Number of molecules	7
	Total formula weight	1889.4
All*	Total formula weight	63008.8

*Water molecules are not included.