4CG4
 
 | | Crystal structure of the CHS-B30.2 domains of TRIM20 | | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-ETHANETHIOL, PYRIN, ... | | 著者 | Weinert, C, Morger, D, Djekic, A, Mittl, P.R.E, Gruetter, M.G. | | 登録日 | 2013-11-20 | | 公開日 | 2015-04-29 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal Structure of Trim20 C-Terminal Coiled-Coil/B30.2 Fragment: Implications for the Recognition of Higher Order Oligomers
Sci.Rep., 5, 2015
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4D49
 | | Crystal structure of computationally designed armadillo repeat proteins for modular peptide recognition. | | 分子名称: | ARGININE, ARMADILLO REPEAT PROTEIN ARM00027, POLY ARG DECAPEPTIDE | | 著者 | Reichen, C, Forzani, C, Zhou, T, Parmeggiani, F, Fleishman, S.J, Mittl, P.R.E, Madhurantakam, C, Honegger, A, Ewald, C, Zerbe, O, Baker, D, Caflisch, A, Pluckthun, A. | | 登録日 | 2014-10-27 | | 公開日 | 2016-01-13 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Computationally Designed Armadillo Repeat Proteins for Modular Peptide Recognition.
J.Mol.Biol., 428, 2016
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4D4E
 | | Crystal structure of computationally designed armadillo repeat proteins for modular peptide recognition. | | 分子名称: | ARMADILLO REPEAT PROTEIN ARM00016, GLYCEROL | | 著者 | Reichen, C, Forzani, C, Zhou, T, Parmeggiani, F, Fleishman, S.J, Mittl, P.R.E, Madhurantakam, C, Honegger, A, Ewald, C, Zerbe, O, Baker, D, Caflisch, A, Pluckthun, A. | | 登録日 | 2014-10-28 | | 公開日 | 2016-01-13 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Computationally Designed Armadillo Repeat Proteins for Modular Peptide Recognition.
J.Mol.Biol., 428, 2016
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6Z4R
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6Z4T
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7AQH
 | | Cell wall binding domain of the Staphylococcal phage 2638A endolysin | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ORF007 | | 著者 | Dunne, M, Sobieraj, A, Ernst, P, Mittl, P.R.E, Pluckthun, A, Loessner, M.J. | | 登録日 | 2020-10-21 | | 公開日 | 2020-12-02 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | | 主引用文献 | Cell wall binding domain of the Staphylococcal phage 2638A endolysin
To Be Published
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7QNL
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2AXI
 | | HDM2 in complex with a beta-hairpin | | 分子名称: | 3[N-MORPHOLINO]PROPANE SULFONIC ACID, SULFATE ION, Ubiquitin-protein ligase E3 Mdm2, ... | | 著者 | Mittl, P.R.E, Fasan, R, Robinson, J, Gruetter, M.G. | | 登録日 | 2005-09-05 | | 公開日 | 2006-03-21 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Structure-Activity Studies in a Family of beta-Hairpin Protein Epitope Mimetic Inhibitors of the p53-HDM2 Protein-Protein Interaction.
Chembiochem, 7, 2006
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1TGK
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1TGJ
 | | HUMAN TRANSFORMING GROWTH FACTOR-BETA 3, CRYSTALLIZED FROM DIOXANE | | 分子名称: | 1,4-DIETHYLENE DIOXIDE, TRANSFORMING GROWTH FACTOR-BETA 3 | | 著者 | Mittl, P.R.E, Priestle, J.P, Gruetter, M.G. | | 登録日 | 1996-07-09 | | 公開日 | 1997-01-11 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The crystal structure of TGF-beta 3 and comparison to TGF-beta 2: implications for receptor binding.
Protein Sci., 5, 1996
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4ATZ
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1C94
 | | REVERSING THE SEQUENCE OF THE GCN4 LEUCINE ZIPPER DOES NOT AFFECT ITS FOLD. | | 分子名称: | RETRO-GCN4 LEUCINE ZIPPER | | 著者 | Mittl, P.R.E, Deillon, C.A, Sargent, D, Liu, N, Klauser, S, Thomas, R.M, Gutte, B, Gruetter, M.G. | | 登録日 | 1999-07-30 | | 公開日 | 2000-03-22 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | | 主引用文献 | The retro-GCN4 leucine zipper sequence forms a stable three-dimensional structure.
Proc.Natl.Acad.Sci.USA, 97, 2000
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1CP3
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1GER
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6HV2
 | | MMP-13 in complex with the peptide IMISF | | 分子名称: | CALCIUM ION, Collagenase 3, GLYCEROL, ... | | 著者 | Mittl, P, Riedl, R, Hohl, D. | | 登録日 | 2018-10-10 | | 公開日 | 2019-01-30 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.709 Å) | | 主引用文献 | Drug Design Inspired by Nature: Crystallographic Detection of an Auto-Tailored Protease Inhibitor Template.
Angew.Chem.Int.Ed.Engl., 58, 2019
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6YE3
 | | IL-2 in complex with a Fab fragment from UFKA-20 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chains: A,D,G, Chains: B,E,H, ... | | 著者 | Karakus, U, Mittl, P, Boyman, O. | | 登録日 | 2020-03-23 | | 公開日 | 2020-12-30 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | | 主引用文献 | Receptor-gated IL-2 delivery by an anti-human IL-2 antibody activates regulatory T cells in three different species.
Sci Transl Med, 12, 2020
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6NW4
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4V3R
 | | Designed armadillo repeat protein with 5 internal repeats, 2nd generation C-cap and 3rd generation N-cap. | | 分子名称: | MAGNESIUM ION, YIII_M5_AII | | 著者 | Reichen, C, Madhurantakam, C, Pluckthun, A, Mittl, P. | | 登録日 | 2014-10-20 | | 公開日 | 2016-01-13 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structures of Designed Armadillo-Repeat Proteins Show Propagation of Inter-Repeat Interface Effects
Acta Crystallogr.,Sect.D, 72, 2016
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4V3O
 | | Designed armadillo repeat protein with 5 internal repeats, 2nd generation C-cap and 3rd generation N-cap. | | 分子名称: | ACETATE ION, CALCIUM ION, YIII_M5_AII | | 著者 | Reichen, C, Madhurantakam, C, Pluckthun, A, Mittl, P. | | 登録日 | 2014-10-20 | | 公開日 | 2016-01-13 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structures of Designed Armadillo-Repeat Proteins Show Propagation of Inter-Repeat Interface Effects
Acta Crystallogr.,Sect.D, 72, 2016
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5AEI
 | | Designed Armadillo repeat protein YIIIM5AII in complex with peptide (KR)5 | | 分子名称: | ACETATE ION, CALCIUM ION, DESIGNED ARMADILLO REPEAT PROTEIN YIIIM5AII, ... | | 著者 | Hansen, S, Tremmel, D, Madhurantakam, C, Reichen, C, Mittl, P, Plueckthun, A. | | 登録日 | 2015-08-31 | | 公開日 | 2016-03-30 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | Structure and Energetic Contributions of a Designed Modular Peptide-Binding Protein with Picomolar Affinity.
J.Am.Chem.Soc., 138, 2016
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2QYJ
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7YWJ
 | | Crystal structure of an engineered TycA variant, TycA pPLA (L313P) | | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, SULFATE ION, ... | | 著者 | Mittl, P, Camus, A, Truong, G, Markert, G, Hilvert, D. | | 登録日 | 2022-02-14 | | 公開日 | 2022-09-21 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.749 Å) | | 主引用文献 | Reprogramming Nonribosomal Peptide Synthetases for Site-Specific Insertion of alpha-Hydroxy Acids.
J.Am.Chem.Soc., 144, 2022
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7YWK
 | | Crystal structure of an engineered TycA variant, TycApPLA, in complex with AMP | | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE MONOPHOSPHATE, CHLORIDE ION, ... | | 著者 | Mittl, P, Camus, A, Truong, G, Markert, G, Hilvert, D. | | 登録日 | 2022-02-14 | | 公開日 | 2022-09-21 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.39 Å) | | 主引用文献 | Reprogramming Nonribosomal Peptide Synthetases for Site-Specific Insertion of alpha-Hydroxy Acids.
J.Am.Chem.Soc., 144, 2022
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7Z7C
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7R0R
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