7YWK
Crystal structure of an engineered TycA variant, TycApPLA, in complex with AMP
Summary for 7YWK
| Entry DOI | 10.2210/pdb7ywk/pdb |
| Descriptor | Tyrocidine synthase 1, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE MONOPHOSPHATE, ... (6 entities in total) |
| Functional Keywords | nonribosomal peptide synthetase, adenylation domain, depsipeptide, ligase |
| Biological source | Brevibacillus parabrevis |
| Total number of polymer chains | 2 |
| Total formula weight | 96501.51 |
| Authors | Mittl, P.,Camus, A.,Truong, G.,Markert, G.,Hilvert, D. (deposition date: 2022-02-14, release date: 2022-09-21, Last modification date: 2024-01-31) |
| Primary citation | Camus, A.,Truong, G.,Mittl, P.R.E.,Markert, G.,Hilvert, D. Reprogramming Nonribosomal Peptide Synthetases for Site-Specific Insertion of alpha-Hydroxy Acids. J.Am.Chem.Soc., 144:17567-17575, 2022 Cited by PubMed: 36070491DOI: 10.1021/jacs.2c07013 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.39 Å) |
Structure validation
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