5XNV
 
 | | Crystal structure of YEATS2 YEATS bound to H3K27ac peptide | | 分子名称: | ALA-ALA-ARG-ALY-SER-ALA-PRO-ALA, AMMONIUM ION, CHLORIDE ION, ... | | 著者 | Li, H.T, Guan, H.P, Zhao, D. | | 登録日 | 2017-05-24 | | 公開日 | 2017-11-01 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.696 Å) | | 主引用文献 | YEATS2 links histone acetylation to tumorigenesis of non-small cell lung cancer.
Nat Commun, 8, 2017
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3OD5
 | | Crystal structure of active caspase-6 bound with Ac-VEID-CHO | | 分子名称: | CACODYLATE ION, Caspase-6, peptide aldehyde inhibitor AC-VEID-CHO | | 著者 | Wang, X.-J, Liu, X, Wang, K.-T, Cao, Q, Su, X.-D. | | 登録日 | 2010-08-11 | | 公開日 | 2010-10-27 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystal structures of human caspase 6 reveal a new mechanism for intramolecular cleavage self-activation
Embo Rep., 11, 2010
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6DS6
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6XKC
 | | Crystal structure of E3 ligase | | 分子名称: | Protein fem-1 homolog C | | 著者 | Yan, X, Dong, A, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Min, J.R, Dong, C, Structural Genomics Consortium (SGC) | | 登録日 | 2020-06-26 | | 公開日 | 2020-10-14 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | Molecular basis for ubiquitin ligase CRL2 FEM1C -mediated recognition of C-degron.
Nat.Chem.Biol., 17, 2021
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6VK3
 | | CryoEM structure of Hrd3/Yos9 complex | | 分子名称: | Hrd3, Protein OS-9 homolog | | 著者 | Wu, X, Rapoport, T.A. | | 登録日 | 2020-01-18 | | 公開日 | 2020-04-29 | | 最終更新日 | 2020-05-06 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structural basis of ER-associated protein degradation mediated by the Hrd1 ubiquitin ligase complex.
Science, 368, 2020
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6VJZ
 | | CryoEM structure of Hrd1-Usa1/Der1/Hrd3 complex of the expected topology | | 分子名称: | Degradation in the endoplasmic reticulum protein 1, ERAD-associated E3 ubiquitin-protein ligase HRD1, ERAD-associated E3 ubiquitin-protein ligase component HRD3, ... | | 著者 | Wu, X, Rapoport, T.A. | | 登録日 | 2020-01-18 | | 公開日 | 2020-04-29 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Structural basis of ER-associated protein degradation mediated by the Hrd1 ubiquitin ligase complex.
Science, 368, 2020
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6VK1
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6VK0
 | | CryoEM structure of Hrd1-Usa1/Der1/Hrd3 of the flipped topology | | 分子名称: | Degradation in the endoplasmic reticulum protein 1, ERAD-associated E3 ubiquitin-protein ligase HRD1, ERAD-associated E3 ubiquitin-protein ligase component HRD3, ... | | 著者 | Wu, X, Rapoport, T.A. | | 登録日 | 2020-01-18 | | 公開日 | 2020-04-29 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Structural basis of ER-associated protein degradation mediated by the Hrd1 ubiquitin ligase complex.
Science, 368, 2020
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6VJY
 | | Cryo-EM structure of Hrd1/Hrd3 monomer | | 分子名称: | ERAD-associated E3 ubiquitin-protein ligase HRD1, ERAD-associated E3 ubiquitin-protein ligase component HRD3 | | 著者 | Wu, X, Rapoport, T.A. | | 登録日 | 2020-01-18 | | 公開日 | 2020-04-29 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Structural basis of ER-associated protein degradation mediated by the Hrd1 ubiquitin ligase complex.
Science, 368, 2020
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6OIE
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5VAE
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5VAF
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7XYT
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3L8A
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5IQL
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6MIN
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6MIU
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6MIM
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6MIO
 | | Crystal structure of Taf14 YEATS domain in complex with histone H3K9pr | | 分子名称: | Histone H3K9pr, Transcription initiation factor TFIID subunit 14 | | 著者 | Klein, B.J, Andrews, F.H, Vann, K.R, Kutateladze, T.G. | | 登録日 | 2018-09-19 | | 公開日 | 2018-11-14 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structural insights into the pi-pi-pi stacking mechanism and DNA-binding activity of the YEATS domain.
Nat Commun, 9, 2018
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6MIQ
 | | Crystal structure of Taf14 YEATS domain in complex with histone H3K9bu | | 分子名称: | Histone H3K9bu, Transcription initiation factor TFIID subunit 14 | | 著者 | Klein, B.J, Andrews, F.H, Vann, K.R, Kutateladze, T.G. | | 登録日 | 2018-09-19 | | 公開日 | 2018-11-14 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Structural insights into the pi-pi-pi stacking mechanism and DNA-binding activity of the YEATS domain.
Nat Commun, 9, 2018
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6MIP
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6MJ7
 | | Crystal structure of p62 ZZ domain in complex with free arginine | | 分子名称: | 1,4-DIETHYLENE DIOXIDE, ARGININE, Sequestosome-1, ... | | 著者 | Ahn, J, Zhang, Y, Kutateladze, T.G. | | 登録日 | 2018-09-20 | | 公開日 | 2018-10-31 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.412 Å) | | 主引用文献 | ZZ-dependent regulation of p62/SQSTM1 in autophagy.
Nat Commun, 9, 2018
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6MIL
 | | Crystal structure of AF9 YEATS domain in complex with histone H3K9bu | | 分子名称: | DI(HYDROXYETHYL)ETHER, Histone H3K9bu, MALONATE ION, ... | | 著者 | Vann, K.R, Klein, B.J, Kutateladze, T.G. | | 登録日 | 2018-09-19 | | 公開日 | 2018-11-14 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Structural insights into the pi-pi-pi stacking mechanism and DNA-binding activity of the YEATS domain.
Nat Commun, 9, 2018
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7Y3C
 | | Crystal structure of TRIM7 bound to RACO-1 | | 分子名称: | E3 ubiquitin-protein ligase TRIM7,E3 ubiquitin-protein ligase TRIM7,TRIM7-RACO-1 | | 著者 | Dong, C, Yan, X. | | 登録日 | 2022-06-10 | | 公開日 | 2022-08-03 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | | 主引用文献 | C-terminal glutamine acts as a C-degron targeted by E3 ubiquitin ligase TRIM7.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7Y3B
 | | Crystal structure of TRIM7 bound to GN1 | | 分子名称: | E3 ubiquitin-protein ligase TRIM7,TRIM7-GN1 | | 著者 | Dong, C, Yan, X. | | 登録日 | 2022-06-10 | | 公開日 | 2022-08-03 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | C-terminal glutamine acts as a C-degron targeted by E3 ubiquitin ligase TRIM7.
Proc.Natl.Acad.Sci.USA, 119, 2022
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