3JD1
| Glutamate dehydrogenase in complex with NADH, closed conformation | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Glutamate dehydrogenase 1, mitochondrial | 著者 | Borgnia, M.J, Banerjee, S, Merk, A, Matthies, D, Bartesaghi, A, Rao, P, Pierson, J, Earl, L.A, Falconieri, V, Subramaniam, S, Milne, J.L.S. | 登録日 | 2016-03-28 | 公開日 | 2016-04-27 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase. Mol.Pharmacol., 89, 2016
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3JCZ
| Structure of bovine glutamate dehydrogenase in the unliganded state | 分子名称: | Glutamate dehydrogenase 1, mitochondrial | 著者 | Borgnia, M.J, Banerjee, S, Merk, A, Matthies, D, Bartesaghi, A, Rao, P, Pierson, J, Earl, L.A, Falconieri, V, Subramaniam, S, Milne, J.L.S. | 登録日 | 2016-03-27 | 公開日 | 2016-04-27 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | 主引用文献 | Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase. Mol.Pharmacol., 89, 2016
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3JD3
| Glutamate dehydrogenase in complex with NADH and GTP, open conformation | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, GUANOSINE-5'-TRIPHOSPHATE, Glutamate dehydrogenase 1, ... | 著者 | Borgnia, M.J, Banerjee, S, Merk, A, Matthies, D, Bartesaghi, A, Rao, P, Pierson, J, Earl, L.A, Falconieri, V, Subramaniam, S, Milne, J.L.S. | 登録日 | 2016-03-28 | 公開日 | 2016-04-27 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase. Mol.Pharmacol., 89, 2016
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3J7H
| Structure of beta-galactosidase at 3.2-A resolution obtained by cryo-electron microscopy | 分子名称: | Beta-galactosidase, MAGNESIUM ION | 著者 | Bartesaghi, A, Matthies, D, Banerjee, S, Merk, A, Subramaniam, S. | 登録日 | 2014-06-30 | 公開日 | 2014-07-30 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structure of beta-galactosidase at 3.2- angstrom resolution obtained by cryo-electron microscopy. Proc.Natl.Acad.Sci.USA, 111, 2014
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3JD2
| Glutamate dehydrogenase in complex with NADH, open conformation | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Glutamate dehydrogenase 1, mitochondrial | 著者 | Borgnia, M.J, Banerjee, S, Merk, A, Matthies, D, Bartesaghi, A, Rao, P, Pierson, J, Earl, L.A, Falconieri, V, Subramaniam, S, Milne, J.L.S. | 登録日 | 2016-03-28 | 公開日 | 2016-04-27 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase. Mol.Pharmacol., 89, 2016
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6X2Z
| hEAAT3-OFS-Asp | 分子名称: | ASPARTIC ACID, Excitatory amino acid transporter 3, SODIUM ION | 著者 | Qiu, B, Matthies, D, Boudker, O. | 登録日 | 2020-05-21 | 公開日 | 2021-03-17 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.03 Å) | 主引用文献 | Cryo-EM structures of excitatory amino acid transporter 3 visualize coupled substrate, sodium, and proton binding and transport. Sci Adv, 7, 2021
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6X3E
| hEAAT3-Asymmetric-1o2i | 分子名称: | ASPARTIC ACID, Excitatory amino acid transporter 3, SODIUM ION | 著者 | Qiu, B, Matthies, D, Boudker, O. | 登録日 | 2020-05-21 | 公開日 | 2021-03-17 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.42 Å) | 主引用文献 | Cryo-EM structures of excitatory amino acid transporter 3 visualize coupled substrate, sodium, and proton binding and transport. Sci Adv, 7, 2021
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6X3F
| hEAAT3-IFS-Apo | 分子名称: | CHOLINE ION, Excitatory amino acid transporter 3 | 著者 | Qiu, B, Matthies, D, Boudker, O. | 登録日 | 2020-05-21 | 公開日 | 2021-03-17 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.03 Å) | 主引用文献 | Cryo-EM structures of excitatory amino acid transporter 3 visualize coupled substrate, sodium, and proton binding and transport. Sci Adv, 7, 2021
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6X2L
| hEAAT3-IFS-Na | 分子名称: | Excitatory amino acid transporter 3 | 著者 | Qiu, B, Matthies, D, Boudker, O. | 登録日 | 2020-05-20 | 公開日 | 2021-03-17 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (2.85 Å) | 主引用文献 | Cryo-EM structures of excitatory amino acid transporter 3 visualize coupled substrate, sodium, and proton binding and transport. Sci Adv, 7, 2021
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7UL1
| Crystal structure of SARS-CoV-2 RBD in complex with the neutralizing IGHV3-53-encoded antibody EH3 isolated from a nonvaccinated pediatric patient | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of EH3, Light chain of EH3, ... | 著者 | Chen, Y, Tolbert, W.D, Pazgier, M. | 登録日 | 2022-04-03 | 公開日 | 2023-03-08 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Molecular basis for antiviral activity of two pediatric neutralizing antibodies targeting SARS-CoV-2 Spike RBD. Iscience, 26, 2023
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7UL0
| Crystal structure of SARS-CoV-2 RBD in complex with the ridge-binding nAb EH8 isolated from a nonvaccinated pediatric patient | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of EH8, ... | 著者 | Chen, Y, Tolbert, W.D, Bai, X, Pazgier, M. | 登録日 | 2022-04-03 | 公開日 | 2023-03-08 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | Molecular basis for antiviral activity of two pediatric neutralizing antibodies targeting SARS-CoV-2 Spike RBD. Iscience, 26, 2023
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8TTW
| Cryo-EM structure of BG505 SOSIP.664 HIV-1 Env trimer in complex with temsavir, 8ANC195, and 10-1074 | 分子名称: | 1-[4-(benzenecarbonyl)piperazin-1-yl]-2-[4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]ethane-1,2-dione, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Tolbert, W.D, Pozharski, E, Pazgier, M. | 登録日 | 2023-08-15 | 公開日 | 2023-11-08 | 実験手法 | ELECTRON MICROSCOPY (2.96 Å) | 主引用文献 | Structure-function analyses reveal key molecular determinants of HIV-1 CRF01_AE resistance to the entry inhibitor temsavir. Nat Commun, 14, 2023
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4ZDP
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4ZDO
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4ZDL
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3ZK2
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3ZK1
| Crystal structure of the sodium binding rotor ring at pH 5.3 | 分子名称: | ATP SYNTHASE SUBUNIT C, DECYL-BETA-D-MALTOPYRANOSIDE, DODECYL-BETA-D-MALTOSIDE, ... | 著者 | Schulz, S, Meier, T, Yildiz, O. | 登録日 | 2013-01-21 | 公開日 | 2013-05-29 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | A New Type of Na(+)-Driven ATP Synthase Membrane Rotor with a Two-Carboxylate Ion-Coupling Motif. Plos Biol., 11, 2013
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4YE6
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4YE9
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4YE8
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8CZZ
| Cryo-EM structure of T/F100 SOSIP.664 HIV-1 Env trimer with LMHS mutations in complex with Temsavir, 8ANC195, and 10-1074 | 分子名称: | 1-[4-(benzenecarbonyl)piperazin-1-yl]-2-[4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]ethane-1,2-dione, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Chen, Y, Pozharski, E, Tolbert, W, Pazgier, M. | 登録日 | 2022-05-25 | 公開日 | 2023-05-31 | 最終更新日 | 2023-11-08 | 実験手法 | ELECTRON MICROSCOPY (3.14 Å) | 主引用文献 | Structure-function analyses reveal key molecular determinants of HIV-1 CRF01_AE resistance to the entry inhibitor temsavir. Nat Commun, 14, 2023
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8DOK
| Cryo-EM structure of T/F100 SOSIP.664 HIV-1 Env trimer in complex with 8ANC195 and 10-1074 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Chen, Y, Zhou, F, Huang, R, Tolbert, W, Pazgier, M. | 登録日 | 2022-07-13 | 公開日 | 2023-07-19 | 最終更新日 | 2023-11-08 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structure-function analyses reveal key molecular determinants of HIV-1 CRF01_AE resistance to the entry inhibitor temsavir. Nat Commun, 14, 2023
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8G6U
| Cryo-EM structure of T/F100 SOSIP.664 HIV-1 Env trimer with LMHS mutations in complex with 8ANC195 and 10-1074 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CRF-1_AE T/F100 HIV-1 gp41, ... | 著者 | Chen, Y, Zhou, F, Huang, R, Tolbert, W, Pazgier, M. | 登録日 | 2023-02-16 | 公開日 | 2023-11-08 | 実験手法 | ELECTRON MICROSCOPY (3.16 Å) | 主引用文献 | Structure-function analyses reveal key molecular determinants of HIV-1 CRF01_AE resistance to the entry inhibitor temsavir. Nat Commun, 14, 2023
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