4ZDL
The crystal structure of the T325S mutant of the human holo SepSecS
Summary for 4ZDL
| Entry DOI | 10.2210/pdb4zdl/pdb |
| Related | 4ZDO 4ZDP |
| Descriptor | O-phosphoseryl-tRNA(Sec) selenium transferase, (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, CITRATE ANION, ... (4 entities in total) |
| Functional Keywords | selenocysteine, pyridoxal phosphate, mutation, transferase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 2 |
| Total formula weight | 112229.79 |
| Authors | French, R.L.,Simonovic, M. (deposition date: 2015-04-17, release date: 2016-04-20, Last modification date: 2023-09-27) |
| Primary citation | Puppala, A.K.,French, R.L.,Matthies, D.,Baxa, U.,Subramaniam, S.,Simonovic, M. Structural basis for early-onset neurological disorders caused by mutations in human selenocysteine synthase. Sci Rep, 6:32563-32563, 2016 Cited by PubMed: 27576344DOI: 10.1038/srep32563 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.26 Å) |
Structure validation
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