4ZDL
The crystal structure of the T325S mutant of the human holo SepSecS
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | O-phosphoseryl-tRNA(Sec) selenium transferase | polymer | 501 | 55787.2 | 2 | UniProt (Q9HD40) Pfam (PF05889) | Homo sapiens (Human) | Liver-pancreas antigen,LP,SLA-p35,SLA/LP autoantigen,Selenocysteine synthase,Sec synthase,Selenocysteinyl-tRNA(Sec) synthase,Sep-tRNA:Sec-tRNA synthase,SepSecS,Soluble liver antigen,SLA,UGA suppressor tRNA-associated protein,tRNA(Ser/Sec)-associated antigenic protein |
| 2 | C, E (A, B) | (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE | non-polymer | 233.2 | 2 | Chemie (PLR) | |||
| 3 | D (A) | CITRATE ANION | non-polymer | 189.1 | 1 | Chemie (FLC) | |||
| 4 | F, G (A, B) | water | water | 18.0 | 530 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 501 (UniProt: Q9HD40)
| PDB | External Database | Details |
|---|---|---|
| Ser 325 | Thr 325 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 111574.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 655.4 | |
| All* | Total formula weight | 112229.8 |
