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4ZDL

The crystal structure of the T325S mutant of the human holo SepSecS

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BO-phosphoseryl-tRNA(Sec) selenium transferasepolymer50155787.22UniProt (Q9HD40)
Pfam (PF05889)
In PDB
Homo sapiens (Human)Liver-pancreas antigen,LP,SLA-p35,SLA/LP autoantigen,Selenocysteine synthase,Sec synthase,Selenocysteinyl-tRNA(Sec) synthase,Sep-tRNA:Sec-tRNA synthase,SepSecS,Soluble liver antigen,SLA,UGA suppressor tRNA-associated protein,tRNA(Ser/Sec)-associated antigenic protein
2A, B(5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATEnon-polymer233.22Chemie (PLR)
3ACITRATE ANIONnon-polymer189.11Chemie (FLC)
4waterwater18.0530Chemie (HOH)
Sequence modifications
A, B: 1 - 501 (UniProt: Q9HD40)
PDBExternal DatabaseDetails
Ser 325Thr 325engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight111574.4
Non-Polymers*Number of molecules3
Total formula weight655.4
All*Total formula weight112229.8
*Water molecules are not included.

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PDB entries from 2024-07-24

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