4ZDP
The crystal structure of Y334C mutant of human SepSecS in complex with selenocysteine tRNA (tRNASec)
Summary for 4ZDP
| Entry DOI | 10.2210/pdb4zdp/pdb |
| Related | 3HL2 4ZDL 4ZDO |
| Descriptor | O-phosphoseryl-tRNA(Sec) selenium transferase, selenocysteine tRNA, (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, ... (5 entities in total) |
| Functional Keywords | selenocysteine, trna, mutation, pyridoxal phosphate, transferase-rna complex, transferase/rna |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 5 |
| Total formula weight | 252245.75 |
| Authors | French, R.L.,Simonovic, M. (deposition date: 2015-04-17, release date: 2016-04-20, Last modification date: 2023-09-27) |
| Primary citation | Puppala, A.K.,French, R.L.,Matthies, D.,Baxa, U.,Subramaniam, S.,Simonovic, M. Structural basis for early-onset neurological disorders caused by mutations in human selenocysteine synthase. Sci Rep, 6:32563-32563, 2016 Cited by PubMed: 27576344DOI: 10.1038/srep32563 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.703 Å) |
Structure validation
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