6M79
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6m79 by Molmil](/molmil-images/mine/6m79) | |
1HQA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1hqa by Molmil](/molmil-images/mine/1hqa) | ALKALINE PHOSPHATASE (H412Q) | Descriptor: | ALKALINE PHOSPHATASE, ZINC ION | Authors: | Ma, L, Kantrowitz, E.R. | Deposit date: | 1995-11-30 | Release date: | 1996-03-08 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Kinetic and X-ray structural studies of a mutant Escherichia coli alkaline phosphatase (His-412-->Gln) at one of the zinc binding sites. Biochemistry, 35, 1996
|
|
1ALI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ali by Molmil](/molmil-images/mine/1ali) | ALKALINE PHOSPHATASE MUTANT (H412N) | Descriptor: | ALKALINE PHOSPHATASE, MAGNESIUM ION, PHOSPHATE ION, ... | Authors: | Ma, L, Tibbitts, T.T, Kantrowitz, E.R. | Deposit date: | 1995-06-02 | Release date: | 1995-11-14 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Escherichia coli alkaline phosphatase: X-ray structural studies of a mutant enzyme (His-412-->Asn) at one of the catalytically important zinc binding sites. Protein Sci., 4, 1995
|
|
1ALJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1alj by Molmil](/molmil-images/mine/1alj) | ALKALINE PHOSPHATASE MUTANT (H412N) | Descriptor: | ALKALINE PHOSPHATASE, MAGNESIUM ION, PHOSPHATE ION, ... | Authors: | Ma, L, Tibbitts, T.T, Kantrowitz, E.R. | Deposit date: | 1995-06-02 | Release date: | 1995-11-14 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Escherichia coli alkaline phosphatase: X-ray structural studies of a mutant enzyme (His-412-->Asn) at one of the catalytically important zinc binding sites. Protein Sci., 4, 1995
|
|
1FA4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1fa4 by Molmil](/molmil-images/mine/1fa4) | ELUCIDATION OF THE PARAMAGNETIC RELAXATION OF HETERONUCLEI AND PROTONS IN CU(II) PLASTOCYANIN FROM ANABAENA VARIABILIS | Descriptor: | COPPER (II) ION, PLASTOCYANIN | Authors: | Ma, L, Jorgensen, A.M, Sorensen, G.O, Ulstrup, J, Led, J.J. | Deposit date: | 2000-07-12 | Release date: | 2000-08-16 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Elucidation of the Paramagnetic R1 Relaxation of Heteronuclei and Protons in Cu(II) Plastocyanin from Anabaena Variabilis J.Am.Chem.Soc., 122, 2000
|
|
1R6R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1r6r by Molmil](/molmil-images/mine/1r6r) | Solution Structure of Dengue Virus Capsid Protein Reveals a New Fold | Descriptor: | Genome polyprotein | Authors: | Ma, L, Jones, C.T, Groesch, T.D, Kuhn, R.J, Post, C.B. | Deposit date: | 2003-10-16 | Release date: | 2004-02-17 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of dengue virus capsid protein reveals another fold Proc.Natl.Acad.Sci.USA, 101, 2004
|
|
8DK4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8dk4 by Molmil](/molmil-images/mine/8dk4) | Peroxisome proliferator-activated receptor gamma in complex with VSP-51-2 | Descriptor: | 5-(benzylcarbamoyl)-1-[(4-chloro-3-fluorophenyl)methyl]-1H-indole-2-carboxylic acid, Peroxisome proliferator-activated receptor gamma, Peroxisome proliferator-activated receptor gamma coactivator 1-alpha | Authors: | Ma, L, Zhou, X.E, Suino-Powell, K, Hou, N, Zhou, Z, Luo, J, Xu, H.E, Yi, W. | Deposit date: | 2022-07-02 | Release date: | 2023-07-05 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Identification of VSP-51-2 as the Novel and Safe PPAR gamma Modulator: Structure-Based Design, Biological Validation and Crystal Analysis To Be Published
|
|
6K8I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6k8i by Molmil](/molmil-images/mine/6k8i) | Crystal structure of Arabidopsis thaliana CRY2 | Descriptor: | Cryptochrome-2, FLAVIN-ADENINE DINUCLEOTIDE | Authors: | Ma, L, Wang, X, Guan, Z, Yin, P. | Deposit date: | 2019-06-12 | Release date: | 2020-05-13 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.697 Å) | Cite: | Structural insights into BIC-mediated inactivation of Arabidopsis cryptochrome 2. Nat.Struct.Mol.Biol., 27, 2020
|
|
7XTQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7xtq by Molmil](/molmil-images/mine/7xtq) | Cryo-EM structure of the R399-bound GPBAR-Gs complex | Descriptor: | G-protein coupled bile acid receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Ma, L, Yang, F, Wu, X, Mao, C, Sun, J, Yu, X, Zhang, Y, Zhang, P. | Deposit date: | 2022-05-17 | Release date: | 2022-07-06 | Last modified: | 2022-08-03 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural basis and molecular mechanism of biased GPBAR signaling in regulating NSCLC cell growth via YAP activity. Proc.Natl.Acad.Sci.USA, 119, 2022
|
|
7VJS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7vjs by Molmil](/molmil-images/mine/7vjs) | Human AlkB homolog ALKBH6 in complex with Tris and Ni | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Alpha-ketoglutarate-dependent dioxygenase alkB homolog 6, NICKEL (II) ION | Authors: | Ma, L, Chen, Z. | Deposit date: | 2021-09-28 | Release date: | 2022-02-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.792 Å) | Cite: | Structural insights into the interactions and epigenetic functions of human nucleic acid repair protein ALKBH6. J.Biol.Chem., 298, 2022
|
|
7VJV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7vjv by Molmil](/molmil-images/mine/7vjv) | Human AlkB homolog ALKBH6 in complex with alpha-katoglutarate and Mn | Descriptor: | 2-OXOGLUTARIC ACID, Alpha-ketoglutarate-dependent dioxygenase alkB homolog 6, MANGANESE (II) ION | Authors: | Ma, L, Chen, Z. | Deposit date: | 2021-09-29 | Release date: | 2022-02-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural insights into the interactions and epigenetic functions of human nucleic acid repair protein ALKBH6. J.Biol.Chem., 298, 2022
|
|
8IFF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8iff by Molmil](/molmil-images/mine/8iff) | Cryo-EM structure of Arabidopsis phytochrome A. | Descriptor: | 3-[5-[[(3~{R},4~{R})-3-ethyl-4-methyl-5-oxidanylidene-3,4-dihydropyrrol-2-yl]methyl]-2-[[5-[(4-ethyl-3-methyl-5-oxidanylidene-pyrrol-2-yl)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1~{H}-pyrrol-2-yl]methyl]-4-methyl-1~{H}-pyrrol-3-yl]propanoic acid, Phytochrome A | Authors: | Ma, L, Zhou, C, Wang, J, Guan, Z, Yin, P. | Deposit date: | 2023-02-17 | Release date: | 2023-08-02 | Last modified: | 2023-10-11 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Plant phytochrome A in the Pr state assembles as an asymmetric dimer. Cell Res., 33, 2023
|
|
6K8K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6k8k by Molmil](/molmil-images/mine/6k8k) | Crystal structure of Arabidopsis thaliana BIC2-CRY2 complex | Descriptor: | ADENOSINE MONOPHOSPHATE, Cryptochrome-2, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Wang, X, Ma, L, Guan, Z, Yin, P. | Deposit date: | 2019-06-12 | Release date: | 2020-05-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural insights into BIC-mediated inactivation of Arabidopsis cryptochrome 2. Nat.Struct.Mol.Biol., 27, 2020
|
|
4ORB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4orb by Molmil](/molmil-images/mine/4orb) | Crystal structure of mouse calcineurin | Descriptor: | CALCIUM ION, Calcineurin subunit B type 1, FE (III) ION, ... | Authors: | Ma, L, Li, S.J, Wang, J, Wu, J.W, Wang, Z.X. | Deposit date: | 2014-02-11 | Release date: | 2015-05-20 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.108 Å) | Cite: | Cooperative autoinhibition and multi-level activation mechanisms of calcineurin To be Published
|
|
4ORC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4orc by Molmil](/molmil-images/mine/4orc) | Crystal structure of mammalian calcineurin | Descriptor: | CALCIUM ION, Calcineurin subunit B type 1, FE (III) ION, ... | Authors: | Ma, L, Li, S.J, Wang, J, Wu, J.W, Wang, Z.X. | Deposit date: | 2014-02-11 | Release date: | 2015-05-20 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Cooperative autoinhibition and multi-level activation mechanisms of calcineurin To be Published
|
|
5WLX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5wlx by Molmil](/molmil-images/mine/5wlx) | |
4PY0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4py0 by Molmil](/molmil-images/mine/4py0) | Crystal structure of P2Y12 receptor in complex with 2MeSATP | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 2-(methylsulfanyl)adenosine 5'-(tetrahydrogen triphosphate), P2Y purinoceptor 12, ... | Authors: | Zhang, J, Zhang, K, Gao, Z.G, Paoletta, S, Zhang, D, Han, G.W, Li, T, Ma, L, Zhang, W, Muller, C.E, Yang, H, Jiang, H, Cherezov, V, Katritch, V, Jacobson, K.A, Stevens, R.C, Wu, B, Zhao, Q, GPCR Network (GPCR) | Deposit date: | 2014-03-25 | Release date: | 2014-04-30 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Agonist-bound structure of the human P2Y12 receptor Nature, 509, 2014
|
|
1NY1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ny1 by Molmil](/molmil-images/mine/1ny1) | CRYSTAL STRUCTURE OF B. SUBTILIS POLYSACCHARIDE DEACETYLASE NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET SR127. | Descriptor: | Probable polysaccharide deacetylase pdaA | Authors: | Forouhar, F, Edstrom, W, Khan, J, Ma, L, Chiang, Y, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2003-02-11 | Release date: | 2003-03-18 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structure of Polysaccharide Deacetylase (PDAA_BACSU) from B. Subtilis (Pdaa_Bacsu) Northeast Structural Genomics Research Consortium (Nesg) Target Sr127 To be Published
|
|
5EZ6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ez6 by Molmil](/molmil-images/mine/5ez6) | Crystallization and preliminary X-ray crystallographic analysis of a small GTPase RhoA | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Transforming protein RhoA | Authors: | Yan, Z, Ma, S, Zhang, Y, Ma, L, Wang, F, Li, J, Miao, L. | Deposit date: | 2015-11-26 | Release date: | 2016-12-07 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystallization and preliminary X-ray crystallographic analysis of a small GTPase RhoA To Be Published
|
|
1HJK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1hjk by Molmil](/molmil-images/mine/1hjk) | ALKALINE PHOSPHATASE MUTANT H331Q | Descriptor: | ALKALINE PHOSPHATASE, MAGNESIUM ION, SULFATE ION, ... | Authors: | Murphy, J.E, Stec, B, Ma, L, Kantrowitz, E.R. | Deposit date: | 1997-05-30 | Release date: | 1997-10-15 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Trapping and visualization of a covalent enzyme-phosphate intermediate. Nat.Struct.Biol., 4, 1997
|
|
1XM3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xm3 by Molmil](/molmil-images/mine/1xm3) | Crystal structure of Northeast Structural Genomics Target SR156 | Descriptor: | Thiazole biosynthesis protein thiG | Authors: | Kuzin, A, Abashidze, M, Vorobiev, S, Forouhar, F, Acton, T, Ma, L, Xiao, R, Montelione, G, Tong, L, Hunt, J, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2004-10-01 | Release date: | 2004-10-19 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of Northeast Structural Genomics Target SR156 To be Published
|
|
1ZKD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1zkd by Molmil](/molmil-images/mine/1zkd) | X-Ray structure of the putative protein Q6N1P6 from Rhodopseudomonas palustris at the resolution 2.1 A , Northeast Structural Genomics Consortium target RpR58 | Descriptor: | DUF185 | Authors: | Kuzin, A.P, Yong, W, Vorobiev, S.M, Acton, T, Ma, L, Xiao, R, Montelione, G, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2005-05-02 | Release date: | 2005-05-10 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | X-Ray structure of the putative protein Q6N1P6 from Rhodopseudomonas palustris at the resolution 2.1 A , Northeast Structural Genomics Consortium target RpR58 To be Published
|
|
1SBK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1sbk by Molmil](/molmil-images/mine/1sbk) | X-RAY STRUCTURE OF YDII_ECOLI NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET ER29. | Descriptor: | Hypothetical protein ydiI, SULFATE ION | Authors: | Kuzin, A.P, Edstrom, W, Vorobiev, S.M, Lee, I, Forouhar, F, Ma, L, Chiang, Y, Rong, X, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2004-02-10 | Release date: | 2004-02-24 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | X-ray Structure of YDII_ECOLI Northeast Structural Genomics Consortium Target ER29 To be Published
|
|
1RZW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1rzw by Molmil](/molmil-images/mine/1rzw) | The Solution Structure of the Archaeglobus fulgidis protein AF2095. Northeast Structural Genomics Consortium target GR4 | Descriptor: | Protein AF2095(GR4) | Authors: | Powers, R, Acton, T.B, Huang, Y.J, Liu, J, Ma, L, Rost, B, Chiang, Y, Cort, J.R, Kennedy, M.A, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2003-12-29 | Release date: | 2004-11-16 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of Archaeglobus fulgidis peptidyl-tRNA hydrolase (Pth2) provides evidence for an extensive conserved family of Pth2 enzymes in archea, bacteria, and eukaryotes Protein Sci., 14, 2005
|
|
3GOC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3goc by Molmil](/molmil-images/mine/3goc) | Crystal structure of the Endonuclease V (SAV1684) from Streptomyces avermitilis. Northeast Structural Genomics Consortium Target SvR196 | Descriptor: | 3-(2-hydroxyethyl)-2,2-bis(hydroxymethyl)pentane-1,5-diol, CHLORIDE ION, Endonuclease V, ... | Authors: | Forouhar, F, Abashidze, M, Hussain, M, Seetharaman, J, Fang, F, Xiao, R, Cunningham, K, Ma, L, Owens, L, Chen, C.X, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2009-03-18 | Release date: | 2009-03-31 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of the Endonuclease V (SAV1684) from Streptomyces avermitilis. Northeast Structural Genomics Consortium Target SvR196. To be Published
|
|