3AL4
 
 | | Crystal structure of the swine-origin A (H1N1)-2009 influenza A virus hemagglutinin (HA) reveals similar antigenicity to that of the 1918 pandemic virus | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... | | Authors: | Zhang, W, Qi, J.X, Shi, Y, Li, Q, Yan, J.H, Gao, G.F. | | Deposit date: | 2010-07-22 | | Release date: | 2010-08-04 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.872 Å) | | Cite: | Crystal structure of the swine-origin A (H1N1)-2009 influenza A virus hemagglutinin (HA) reveals similar antigenicity to that of the 1918 pandemic virus
Protein Cell, 1, 2010
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3BU7
 | | Crystal Structure and Biochemical Characterization of GDOsp, a Gentisate 1,2-Dioxygenase from Silicibacter Pomeroyi | | Descriptor: | FE (II) ION, Gentisate 1,2-dioxygenase | | Authors: | Chen, J, Wang, M.Z, Zhu, G.Y, Zhang, X.C, Rao, Z.H. | | Deposit date: | 2008-01-02 | | Release date: | 2008-08-12 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal structure and mutagenic analysis of GDOsp, a gentisate 1,2-dioxygenase from Silicibacter pomeroyi.
Protein Sci., 17, 2008
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3CRY
 | | Gamma-glutamyl cyclotransferase | | Descriptor: | ACETATE ION, Gamma-glutamyl cyclotransferase | | Authors: | Oakley, A.J, Board, P.G. | | Deposit date: | 2008-04-08 | | Release date: | 2008-04-29 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | The identification and structural characterization of C7orf24 as gamma-glutamyl cyclotransferase. An essential enzyme in the gamma-glutamyl cycle
J.Biol.Chem., 283, 2008
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3EIJ
 | | Crystal structure of Pdcd4 | | Descriptor: | Programmed cell death protein 4 | | Authors: | Loh, P.G. | | Deposit date: | 2008-09-16 | | Release date: | 2009-02-17 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural basis for translational inhibition by the tumour suppressor Pdcd4
Embo J., 28, 2009
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3EIQ
 | | Crystal structure of Pdcd4-eIF4A | | Descriptor: | Eukaryotic initiation factor 4A-I, Programmed cell death protein 4 | | Authors: | Loh, P.G, Cheng, Z, Song, H. | | Deposit date: | 2008-09-17 | | Release date: | 2009-02-24 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Structural basis for translational inhibition by the tumour suppressor Pdcd4
Embo J., 28, 2009
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6CHC
 | | JzTx-V toxin peptide, wild-type | | Descriptor: | Beta/kappa-theraphotoxin-Cg2a | | Authors: | Jordan, J.B. | | Deposit date: | 2018-02-22 | | Release date: | 2018-05-16 | | Method: | SOLUTION NMR | | Cite: | Pharmacological characterization of potent and selective NaV1.7 inhibitors engineered from Chilobrachys jingzhao tarantula venom peptide JzTx-V.
PLoS ONE, 13, 2018
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6CNU
 | | Crystal Structure of JzTX-V | | Descriptor: | BROMIDE ION, GLYCEROL, JzTx-V, ... | | Authors: | Min, X, Wang, Z. | | Deposit date: | 2018-03-09 | | Release date: | 2019-03-06 | | Last modified: | 2020-03-04 | | Method: | X-RAY DIFFRACTION (1.05 Å) | | Cite: | Discovery of Tarantula Venom-Derived NaV1.7-Inhibitory JzTx-V Peptide 5-Br-Trp24 Analogue AM-6120 with Systemic Block of Histamine-Induced Pruritis.
J. Med. Chem., 61, 2018
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5YMR
 | | The Crystal Structure of IseG | | Descriptor: | 2-hydroxyethylsulfonic acid, Formate acetyltransferase, GLYCEROL | | Authors: | Lin, L, Zhang, J, Xing, M, Hua, G, Guo, C, Hu, Y, Wei, Y, Ang, E, Zhao, H, Zhang, Y, Yuchi, Z. | | Deposit date: | 2017-10-22 | | Release date: | 2019-03-20 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Radical-mediated C-S bond cleavage in C2 sulfonate degradation by anaerobic bacteria.
Nat Commun, 10, 2019
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6ACU
 | | The structure of CVA10 virus mature virion | | Descriptor: | SPHINGOSINE, VP1, VP2, ... | | Authors: | Cui, Y.X, Zheng, Q.B, Zhu, R, Xu, L.F, Li, S.W, Yan, X.D, Zhou, Z.H, Cheng, T. | | Deposit date: | 2018-07-27 | | Release date: | 2018-11-21 | | Last modified: | 2022-03-23 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Discovery and structural characterization of a therapeutic antibody against coxsackievirus A10.
Sci Adv, 4, 2018
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6ACW
 | | The structure of CVA10 virus procapsid particle | | Descriptor: | VP0, VP1, VP3 | | Authors: | Zhu, R, Xu, L.F, Zheng, Q.B, Cui, Y.X, Li, S.W, Yan, X.D, Zhou, Z.H, Cheng, T. | | Deposit date: | 2018-07-27 | | Release date: | 2018-11-21 | | Last modified: | 2022-03-23 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Discovery and structural characterization of a therapeutic antibody against coxsackievirus A10.
Sci Adv, 4, 2018
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6AD1
 | | The structure of CVA10 procapsid from its complex with Fab 2G8 | | Descriptor: | VP0, VP1, VP3 | | Authors: | Zhu, R, Zheng, Q.B, Xu, L.F, Cui, Y.X, Li, S.W, Yan, X.D, Zhou, Z.H, Cheng, T. | | Deposit date: | 2018-07-28 | | Release date: | 2018-11-21 | | Last modified: | 2022-03-23 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Discovery and structural characterization of a therapeutic antibody against coxsackievirus A10.
Sci Adv, 4, 2018
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7DJZ
 | | Crystal structure of SARS-CoV-2 Spike RBD in complex with MW01 Fab | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CITRIC ACID, MW01 heavy chain, ... | | Authors: | Wang, J, Jiao, S, Wang, R, Zhang, J, Zhang, M, Wang, M. | | Deposit date: | 2020-11-22 | | Release date: | 2021-06-09 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.397 Å) | | Cite: | Antibody-dependent enhancement (ADE) of SARS-CoV-2 pseudoviral infection requires Fc gamma RIIB and virus-antibody complex with bivalent interaction.
Commun Biol, 5, 2022
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6AD0
 | | The structure of CVA10 mature virion in complex with Fab 2G8 | | Descriptor: | SPHINGOSINE, VH of Fab 2G8, VL of Fab 2G8, ... | | Authors: | Zhu, R, Zheng, Q.B, Xu, L.F, Cui, Y.X, Li, S.W, Yan, X.D, Zhou, Z.H, Cheng, T. | | Deposit date: | 2018-07-28 | | Release date: | 2018-11-21 | | Last modified: | 2022-03-23 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Discovery and structural characterization of a therapeutic antibody against coxsackievirus A10.
Sci Adv, 4, 2018
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6ACZ
 | | The structure of CVA10 virus A-particle from its complex with Fab 2G8 | | Descriptor: | VP1, VP2, VP3 | | Authors: | Zhu, R, Zheng, Q.B, Xu, L.F, Cui, Y.X, Li, S.W, Yan, X.D, Zhou, Z.H, Cheng, T. | | Deposit date: | 2018-07-28 | | Release date: | 2018-11-21 | | Last modified: | 2022-03-23 | | Method: | ELECTRON MICROSCOPY (4.3 Å) | | Cite: | Discovery and structural characterization of a therapeutic antibody against coxsackievirus A10.
Sci Adv, 4, 2018
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6ACY
 | | The structure of CVA10 virus A-particle | | Descriptor: | VP1, VP2, VP3 | | Authors: | Cui, Y.X, Zheng, Q.B, Zhu, R, Xu, L.F, Li, S.W, Yan, X.D, Zhou, Z.H, Cheng, T. | | Deposit date: | 2018-07-28 | | Release date: | 2018-11-21 | | Last modified: | 2022-03-23 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Discovery and structural characterization of a therapeutic antibody against coxsackievirus A10.
Sci Adv, 4, 2018
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6GG8
 | | Mineralocorticoid receptor in complex with (s)-13 | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Mineralocorticoid receptor, Nuclear receptor coactivator 1, ... | | Authors: | Edman, K, Aagaard, A, Tangefjord, S. | | Deposit date: | 2018-05-03 | | Release date: | 2019-01-09 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Identification of Mineralocorticoid Receptor Modulators with Low Impact on Electrolyte Homeostasis but Maintained Organ Protection.
J.Med.Chem., 62, 2019
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6GEV
 | | Mineralocorticoid receptor in complex with (s)-13 | | Descriptor: | 6-[[(3~{S})-7-fluoranyl-3-(2-methylpropyl)-2,3-dihydro-1,4-benzoxazin-4-yl]carbonyl]-4~{H}-1,4-benzoxazin-3-one, GLYCEROL, Mineralocorticoid receptor, ... | | Authors: | Edman, K, Aagaard, A, Tangefjord, S. | | Deposit date: | 2018-04-27 | | Release date: | 2019-01-09 | | Last modified: | 2019-04-24 | | Method: | X-RAY DIFFRACTION (1.54 Å) | | Cite: | Identification of Mineralocorticoid Receptor Modulators with Low Impact on Electrolyte Homeostasis but Maintained Organ Protection.
J.Med.Chem., 62, 2019
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6GGG
 | | Mineralocorticoid receptor in complex with (s)-13 | | Descriptor: | 2-[(3~{S})-7-fluoranyl-6-(2-methylpropyl)-4-[(3-oxidanylidene-4~{H}-1,4-benzoxazin-6-yl)carbonyl]-2,3-dihydro-1,4-benzoxazin-3-yl]-~{N}-methyl-ethanamide, CHLORIDE ION, Mineralocorticoid receptor, ... | | Authors: | Edman, K, Aagaard, A, Tangefjord, S. | | Deposit date: | 2018-05-03 | | Release date: | 2019-01-09 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.71 Å) | | Cite: | Identification of Mineralocorticoid Receptor Modulators with Low Impact on Electrolyte Homeostasis but Maintained Organ Protection.
J.Med.Chem., 62, 2019
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6KIK
 | | Crystal structure of a thermostable aldo-keto reductase Tm1743 in complex with inhibitor tolrestat | | Descriptor: | Oxidoreductase, aldo/keto reductase family, TOLRESTAT | | Authors: | Zhang, C.Y, Liu, X.M, Wang, C, Tang, W.R. | | Deposit date: | 2019-07-18 | | Release date: | 2019-09-25 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.601 Å) | | Cite: | Tolrestat acts atypically as a competitive inhibitor of the thermostable aldo-keto reductase Tm1743 from Thermotoga maritima.
Febs Lett., 594, 2020
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6KIY
 | | Crystal structure of a thermostable aldo-keto reductase Tm1743 in complex with inhibitor Epalrestat | | Descriptor: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Oxidoreductase, aldo/keto reductase family, ... | | Authors: | Zhang, C.Y, Liu, X.M, Wang, C, Min, Z.Z, Xu, X.L. | | Deposit date: | 2019-07-20 | | Release date: | 2019-09-25 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Tolrestat acts atypically as a competitive inhibitor of the thermostable aldo-keto reductase Tm1743 from Thermotoga maritima.
Febs Lett., 594, 2020
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6KY6
 | | Crystal structure of a thermostable aldo-keto reductase Tm1743 in complexs with inhibitor epalrestat in space group P3221cc | | Descriptor: | 2,5-diketo-D-gluconic acid reductase, CHLORIDE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | Authors: | Zhang, C.Y, Min, Z.Z, Liu, X.M, Wang, C, Tang, W.R. | | Deposit date: | 2019-09-16 | | Release date: | 2019-10-02 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.07 Å) | | Cite: | Tolrestat acts atypically as a competitive inhibitor of the thermostable aldo-keto reductase Tm1743 from Thermotoga maritima.
Febs Lett., 594, 2020
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7VKG
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5Y6P
 | | Structure of the phycobilisome from the red alga Griffithsia pacifica | | Descriptor: | ApcD, ApcF, LC, ... | | Authors: | Zhang, J, Ma, J.F, Liu, D.S, Sun, S, Sui, S.F. | | Deposit date: | 2017-08-13 | | Release date: | 2017-11-15 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Structure of phycobilisome from the red alga Griffithsia pacifica
Nature, 551, 2017
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8HMP
 | | GPR52 with Gs and c17 | | Descriptor: | G-protein coupled receptor 52, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Chen, B, Xu, F. | | Deposit date: | 2022-12-05 | | Release date: | 2023-06-21 | | Method: | ELECTRON MICROSCOPY (2.77 Å) | | Cite: | Allosteric coupling between G-protein binding and extracellular ligand binding sites in GPR52 revealed by 19 F-NMR and cryo-electron microscopy.
MedComm (2020), 4, 2023
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2PN7
 | | Human gamma-glutamyl cyclotransferase | | Descriptor: | human gamma-glutamyl cyclotransferase | | Authors: | Oakley, A.J, Board, P.G. | | Deposit date: | 2007-04-24 | | Release date: | 2007-05-01 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.41 Å) | | Cite: | The identification and structural characterization of C7orf24 as gamma-glutamyl cyclotransferase. An essential enzyme in the gamma-glutamyl cycle.
J.Biol.Chem., 283, 2008
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