8H3S
| Substrate-bound EP, polyA model | Descriptor: | Enteropeptidase catalytic light chain, Enteropeptidase non-catalytic heavy chain, Serine protease 1 | Authors: | Ding, Z.Y, Huang, H.J. | Deposit date: | 2022-10-09 | Release date: | 2022-11-23 | Method: | ELECTRON MICROSCOPY (4.9 Å) | Cite: | Cryo-EM structures reveal the activation and substrate recognition mechanism of human enteropeptidase. Nat Commun, 13, 2022
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8HEF
| The Crystal structure of deuterated S-217622 (Ensitrelvir) bound to the main protease (3CLpro/Mpro) of SARS-CoV-2 | Descriptor: | 3C-like proteinase, 6-[(6-chloranyl-2-methyl-indazol-5-yl)amino]-3-[(1-methyl-1,2,4-triazol-3-yl)methyl]-1-[[2,4,5-tris(fluoranyl)phenyl]methyl]-1,3,5-triazine-2,4-dione, GLYCEROL | Authors: | Yan, M, Zhang, H. | Deposit date: | 2022-11-08 | Release date: | 2023-04-19 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | Synthesis of deuterated S-217622 (Ensitrelvir) with antiviral activity against coronaviruses including SARS-CoV-2. Antiviral Res., 213, 2023
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7VKP
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7W93
| Crystal structure of E.coli pseudouridine kinase PsuK complexed with N1-methyl-pseudouridine | Descriptor: | 5-[(2S,3R,4S,5R)-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolan-2-yl]-1-methyl-pyrimidine-2,4-dione, POTASSIUM ION, PfkB domain protein | Authors: | Li, K.J, Li, X.J, Wu, B.X. | Deposit date: | 2021-12-09 | Release date: | 2022-06-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure Characterization of Escherichia coli Pseudouridine Kinase PsuK. Front Microbiol, 13, 2022
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7VSK
| Crystal structure of E.coli pseudouridine kinase PsuK complexed with pseudouridine. | Descriptor: | 5-[(2~{S},3~{R},4~{S},5~{R})-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolan-2-yl]-1~{H}-pyrimidine-2,4-dione, PfkB domain protein | Authors: | Li, K.J, Li, X.J, Wu, B.X. | Deposit date: | 2021-10-26 | Release date: | 2022-06-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | Structure Characterization of Escherichia coli Pseudouridine Kinase PsuK. Front Microbiol, 13, 2022
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5TOU
| STRUCTURE OF C-PHYCOCYANIN FROM ARCTIC PSEUDANABAENA SP. LW0831 | Descriptor: | PHYCOCYANOBILIN, Phycocyanin alpha-1 subunit, Phycocyanin beta-1 subunit | Authors: | Wang, Q.M, Li, C.Y, Su, H.N, Zhang, Y.Z, Xie, B.B. | Deposit date: | 2016-10-18 | Release date: | 2017-03-08 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Structural insights into the cold adaptation of the photosynthetic pigment-protein C-phycocyanin from an Arctic cyanobacterium Biochim. Biophys. Acta, 1858, 2017
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8F9W
| Crystal structure of Ky15.8 Fab in complex with circumsporozoite protein NPDP peptide | Descriptor: | 1,2-ETHANEDIOL, Circumsporozoite protein NPDP peptide, Ky15.8 Antibody, ... | Authors: | Thai, E, Prieto, K, Julien, J.P. | Deposit date: | 2022-11-24 | Release date: | 2023-11-01 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Molecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein. Cell Rep, 42, 2023
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8FA9
| Crystal structure of Ky15.5 Fab in complex with circumsporozoite protein NPDP peptide | Descriptor: | Circumsporozoite protein NPDP peptide, Ky15.5 Antibody, heavy chain, ... | Authors: | Thai, E, Prieto, K, Julien, J.P. | Deposit date: | 2022-11-25 | Release date: | 2023-11-01 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Molecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein. Cell Rep, 42, 2023
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8F9V
| Crystal structure of Ky15.8 Fab in complex with circumsporozoite protein KQPA peptide | Descriptor: | 1,2-ETHANEDIOL, Circumsporozoite protein KQPA peptide, Ky15.8 Antibody, ... | Authors: | Thai, E, Prieto, K, Julien, J.P. | Deposit date: | 2022-11-24 | Release date: | 2023-11-01 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Molecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein. Cell Rep, 42, 2023
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8FA6
| Crystal structure of Ky15.10 Fab in complex with circumsporozoite protein DND peptide | Descriptor: | 1,2-ETHANEDIOL, Circumsporozoite protein DND peptide, Ky15.10 Antibody, ... | Authors: | Thai, E, Prieto, K, Julien, J.P. | Deposit date: | 2022-11-25 | Release date: | 2023-11-01 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Molecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein. Cell Rep, 42, 2023
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8FB6
| Crystal structure of Ky15.10 Fab in complex with circumsporozoite protein KQPA peptide | Descriptor: | 1,2-ETHANEDIOL, Circumsporozoite protein KQPA peptide, Ky15.10 Antibody, ... | Authors: | Prieto, K, Thai, E, Julien, J.P. | Deposit date: | 2022-11-29 | Release date: | 2023-11-01 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Molecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein. Cell Rep, 42, 2023
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8FB7
| Crystal structure of Ky15.10 Fab in complex with circumsporozoite protein NPDP peptide | Descriptor: | 1,2-ETHANEDIOL, Circumsporozoite protein NPDP peptide, Ky15.10 Antibody, ... | Authors: | Prieto, K, Thai, E, Julien, J.P. | Deposit date: | 2022-11-29 | Release date: | 2023-11-01 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Molecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein. Cell Rep, 42, 2023
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7N8E
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7N8M
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7N8L
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7VVX
| MmtN-SAH-Met complex | Descriptor: | METHIONINE, PHOSPHATE ION, S-ADENOSYL-L-HOMOCYSTEINE, ... | Authors: | Zhang, Y.Z, Peng, M, Li, C.Y. | Deposit date: | 2021-11-09 | Release date: | 2022-04-20 | Last modified: | 2022-08-24 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Insights into methionine S-methylation in diverse organisms. Nat Commun, 13, 2022
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7VVV
| Crystal structure of MmtN | Descriptor: | PHOSPHATE ION, SAM-dependent methyltransferase | Authors: | Peng, M, Li, C.Y. | Deposit date: | 2021-11-09 | Release date: | 2022-04-20 | Last modified: | 2022-08-24 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Insights into methionine S-methylation in diverse organisms. Nat Commun, 13, 2022
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7VVW
| MmtN-SAM complex | Descriptor: | GLYCEROL, PHOSPHATE ION, S-ADENOSYLMETHIONINE, ... | Authors: | Zhang, Y.Z, Peng, M, Li, C.Y. | Deposit date: | 2021-11-09 | Release date: | 2022-04-20 | Last modified: | 2022-08-24 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | Insights into methionine S-methylation in diverse organisms. Nat Commun, 13, 2022
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2JKI
| Complex of Hsp90 N-terminal and Sgt1 CS domain | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CYTOSOLIC HEAT SHOCK PROTEIN 90, SGT1-LIKE PROTEIN | Authors: | Zhang, M, Pearl, L.H. | Deposit date: | 2008-08-28 | Release date: | 2008-10-07 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural and Functional Coupling of Hsp90- and Sgt1-Centred Multi-Protein Complexes. Embo J., 27, 2008
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8EFP
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8VJR
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5XXH
| Crystal Structure Analysis of the CBP | Descriptor: | (3S)-1-[2-(3-ethanoylindol-1-yl)ethanoyl]piperidine-3-carboxylic acid, 1,2-ETHANEDIOL, CREB-binding protein, ... | Authors: | Xiang, Q, Zhang, Y, Wang, C, Song, M. | Deposit date: | 2017-07-04 | Release date: | 2018-06-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | Discovery and optimization of 1-(1H-indol-1-yl)ethanone derivatives as CBP/EP300 bromodomain inhibitors for the treatment of castration-resistant prostate cancer. Eur J Med Chem, 147, 2018
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8VGR
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8VJS
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8ET1
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