7T3O
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7T3N
| R184Q/E191Q mutant of rat vesicular glutamate transporter 2 (VGLUT2) | 分子名称: | (1S,3R)-1-AMINOCYCLOPENTANE-1,3-DICARBOXYLIC ACID, (2R)-2-(methoxymethyl)-4-{[(25R)-spirost-5-en-3beta-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside, Vesicular glutamate transporter 2 | 著者 | Li, F, Stroud, R.M, Edwards, R.H. | 登録日 | 2021-12-08 | 公開日 | 2022-12-14 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Substrate Recognition, Directional Flux, and Allostery in a Synaptic Vesicle Glutamate Transporter To Be Published
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3D0I
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3D0G
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8SBE
| Structure of the rat vesicular glutamate transporter 2 determined by single-particle Cryo-EM | 分子名称: | Vesicular glutamate transporter 2 | 著者 | Li, F, Finer-Moore, J, Eriksen, J, Cheng, Y, Edwards, R, Stroud, R. | 登録日 | 2023-04-03 | 公開日 | 2023-05-03 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Ion transport and regulation in a synaptic vesicle glutamate transporter. Science, 368, 2020
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5DUO
| Crystal structure of native translocator protein 18kDa (TSPO) from Rhodobacter sphaeroides (A139T Mutant) in C2 space group | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, FORMIC ACID, PROTOPORPHYRIN IX, ... | 著者 | Li, F, Liu, J, Zheng, Y, Garavito, R.M, Ferguson-Miller, S. | 登録日 | 2015-09-20 | 公開日 | 2015-11-11 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Response to Comment on "Crystal structures of translocator protein (TSPO) and mutant mimic of a human polymorphism". Science, 350, 2015
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5EOA
| Crystal structure of OPTN E50K mutant and TBK1 complex | 分子名称: | Optineurin, Serine/threonine-protein kinase TBK1 | 著者 | Li, F, Xie, X, Liu, J, Pan, L. | 登録日 | 2015-11-10 | 公開日 | 2016-09-28 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.503 Å) | 主引用文献 | Structural insights into the interaction and disease mechanism of neurodegenerative disease-associated optineurin and TBK1 proteins. Nat Commun, 7, 2016
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4ROU
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5EP6
| The crystal structure of NAP1 in complex with TBK1 | 分子名称: | 5-azacytidine-induced protein 2, GLYCEROL, Serine/threonine-protein kinase TBK1 | 著者 | Li, F, Xie, X, Liu, J, Pan, L. | 登録日 | 2015-11-11 | 公開日 | 2016-09-28 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.451 Å) | 主引用文献 | Structural insights into the interaction and disease mechanism of neurodegenerative disease-associated optineurin and TBK1 proteins. Nat Commun, 7, 2016
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5EOF
| Crystal structure of OPTN NTD and TBK1 CTD complex | 分子名称: | Optineurin, Serine/threonine-protein kinase TBK1 | 著者 | Li, F, Xie, X, Liu, J, Pan, L. | 登録日 | 2015-11-10 | 公開日 | 2016-09-28 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Structural insights into the interaction and disease mechanism of neurodegenerative disease-associated optineurin and TBK1 proteins. Nat Commun, 7, 2016
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6MDW
| Mechanism of protease dependent DPC repair | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, CITRATE ANION, ... | 著者 | Li, F, Raczynska, J, Chen, Z, Yu, H. | 登録日 | 2018-09-05 | 公開日 | 2019-04-10 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural Insight into DNA-Dependent Activation of Human Metalloprotease Spartan. Cell Rep, 26, 2019
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6MDX
| Mechanism of protease dependent DPC repair | 分子名称: | 1,2-ETHANEDIOL, CITRATE ANION, DNA (5'-D(P*CP*C)-3'), ... | 著者 | Li, F, Raczynska, J, Chen, Z, Yu, H. | 登録日 | 2018-09-05 | 公開日 | 2019-04-10 | 最終更新日 | 2019-12-18 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Structural Insight into DNA-Dependent Activation of Human Metalloprotease Spartan. Cell Rep, 26, 2019
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6OCG
| Crystal structure of VASH1-SVBP complex bound with EpoY | 分子名称: | CHLORIDE ION, GLYCEROL, N-[(3R)-4-ethoxy-3-hydroxy-4-oxobutanoyl]-L-tyrosine, ... | 著者 | Li, F, Luo, X, Yu, H. | 登録日 | 2019-03-23 | 公開日 | 2019-06-26 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.833 Å) | 主引用文献 | Structural basis of tubulin detyrosination by vasohibins. Nat.Struct.Mol.Biol., 26, 2019
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6OCF
| The crystal structure of VASH1-SVBP complex | 分子名称: | CHLORIDE ION, GLYCEROL, Small vasohibin-binding protein, ... | 著者 | Li, F, Luo, X, Yu, H. | 登録日 | 2019-03-23 | 公開日 | 2019-06-26 | 最終更新日 | 2019-12-18 | 実験手法 | X-RAY DIFFRACTION (2.102 Å) | 主引用文献 | Structural basis of tubulin detyrosination by vasohibins. Nat.Struct.Mol.Biol., 26, 2019
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6OCH
| Crystal structure of VASH1-SVBP complex bound with parthenolide | 分子名称: | GLYCEROL, SULFATE ION, Small vasohibin-binding protein, ... | 著者 | Li, F, Luo, X, Yu, H. | 登録日 | 2019-03-23 | 公開日 | 2019-06-26 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.003 Å) | 主引用文献 | Structural basis of tubulin detyrosination by vasohibins. Nat.Struct.Mol.Biol., 26, 2019
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5WQ4
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8HR5
| Cryo-EM structure of the CnCas12f1-sgRNA-DNA complex | 分子名称: | DNA (28-MER), DNA (5'-D(*TP*AP*AP*CP*CP*TP*AP*AP*TP*AP*GP*AP*TP*GP*TP*GP*AP*A)-3'), Transposase, ... | 著者 | Li, F, Ji, Q. | 登録日 | 2022-12-14 | 公開日 | 2023-09-06 | 実験手法 | ELECTRON MICROSCOPY (3.73 Å) | 主引用文献 | Structure and engineering of miniature Clostridium novyi CRISPR-Cas12f1 with rare C-rich PAM specificity To Be Published
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7UKJ
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4HJR
| Crystal structure of F2YRS | 分子名称: | Tyrosine-tRNA ligase | 著者 | Wang, J, Tian, C, Gong, W, Li, F, Shi, P, Li, J, Ding, W. | 登録日 | 2012-10-13 | 公開日 | 2013-03-13 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | A genetically encoded 19F NMR probe for tyrosine phosphorylation. Angew.Chem.Int.Ed.Engl., 52, 2013
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4HJX
| Crystal structure of F2YRS complexed with F2Y | 分子名称: | 3,5-difluoro-L-tyrosine, Tyrosine-tRNA ligase | 著者 | Wang, J, Tian, C, Gong, W, Li, F, Shi, P, Li, J, Ding, W. | 登録日 | 2012-10-14 | 公開日 | 2013-03-13 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | 主引用文献 | A genetically encoded 19F NMR probe for tyrosine phosphorylation. Angew.Chem.Int.Ed.Engl., 52, 2013
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8UCD
| Cryo-EM structure of human STEAP1 in complex with AMG 509 Fab | 分子名称: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, AMG 509 anti-STEAP1 Fab, heavy chain, ... | 著者 | Li, F, Bailis, J.M, Zhang, H. | 登録日 | 2023-09-26 | 公開日 | 2023-11-22 | 最終更新日 | 2024-01-24 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | AMG 509 (Xaluritamig), an Anti-STEAP1 XmAb 2+1 T-cell Redirecting Immune Therapy with Avidity-Dependent Activity against Prostate Cancer. Cancer Discov, 14, 2024
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4ZRI
| Crystal structure of Merlin-FERM and Lats2 | 分子名称: | Merlin, Serine/threonine-protein kinase LATS2 | 著者 | Li, F, Zhou, H, Long, J, Shen, Y. | 登録日 | 2015-05-12 | 公開日 | 2015-06-17 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Angiomotin binding-induced activation of Merlin/NF2 in the Hippo pathway Cell Res., 25, 2015
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8QMZ
| Soluble epoxide hydrolase in complex with RK4 | 分子名称: | (3~{a}~{R},6~{a}~{S})-~{N}-[(2,4-dichlorophenyl)methyl]-2-(4-methylphenyl)sulfonyl-3,3~{a},4,5,6,6~{a}-hexahydro-1~{H}-cyclopenta[c]pyrrole-5-carboxamide, 1,2-ETHANEDIOL, Bifunctional epoxide hydrolase 2 | 著者 | Kumar, A, Zhu, F, Ehrler, J.M.H, Li, F, Empel, C, Xu, Y, Atodiresei, I, Koenigs, R.M, Proschak, E, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2023-09-25 | 公開日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | 主引用文献 | Photosensitization enables Pauson-Khand-type reactions with nitrenes. Science, 383, 2024
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8QN0
| Soluble epoxide hydrolase in complex with RK3 | 分子名称: | (3~{a}~{R},6~{a}~{S})-~{N}-[(2,4-dichlorophenyl)methyl]-5-(4-methylphenyl)sulfonyl-1,3,3~{a},4,6,6~{a}-hexahydropyrrolo[3,4-c]pyrrole-2-carboxamide, 1,2-ETHANEDIOL, Bifunctional epoxide hydrolase 2 | 著者 | Kumar, A, Zhu, F, Ehrler, J.M.H, Li, F, Empel, C, Xu, Y, Atodiresei, I, Koenigs, R.M, Proschak, E, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2023-09-25 | 公開日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | 主引用文献 | Photosensitization enables Pauson-Khand-type reactions with nitrenes. Science, 383, 2024
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4RVZ
| Crystal structure of tRNA fluorescent labeling enzyme | 分子名称: | MAGNESIUM ION, N-(4-aminobutyl)-2-azidoacetamide, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... | 著者 | Dong, J, Li, F, Wang, J, Gong, W. | 登録日 | 2014-11-29 | 公開日 | 2015-03-11 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | A covalent approach for site-specific RNA labeling in Mammalian cells. Angew.Chem.Int.Ed.Engl., 54, 2015
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