8QN0

Soluble epoxide hydrolase in complex with RK3

Summary for 8QN0

• Entry DOI: 10.2210/pdb8qn0/pdb
• Related: 8QMZ
• Descriptor: Bifunctional epoxide hydrolase 2, (3~{a}~{R},6~{a}~{S})-~{N}-[(2,4-dichlorophenyl)methyl]-5-(4-methylphenyl)sulfonyl-1,3,3~{a},4,6,6~{a}-hexahydropyrrolo[3,4-c]pyrrole-2-carboxamide, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: complex, structural genomics, structural genomics consortium, sgc, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 85211.37

Authors

Kumar, A.,Zhu, F.,Ehrler, J.M.H.,Li, F.,Empel, C.,Xu, Y.,Atodiresei, I.,Koenigs, R.M.,Proschak, E.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2023-09-25, release date: 2024-02-14)

• Primary citation: Li, F.,Zhu, W.F.,Empel, C.,Datsenko, O.,Kumar, A.,Xu, Y.,Ehrler, J.H.M.,Atodiresei, I.,Knapp, S.,Mykhailiuk, P.K.,Proschak, E.,Koenigs, R.M.; Photosensitization enables Pauson-Khand-type reactions with nitrenes.; Science, 383:498-503, 2024; PubMed: 38301027; DOI: 10.1126/science.adm8095

Experimental method

X-RAY DIFFRACTION (1.49 Å)