1LBH
| INTACT LACTOSE OPERON REPRESSOR WITH GRATUITOUS INDUCER IPTG | Descriptor: | 1-methylethyl 1-thio-beta-D-galactopyranoside, INTACT LACTOSE OPERON REPRESSOR WITH GRATUITOUS INDUCER IPTG | Authors: | Lewis, M, Chang, G, Horton, N.C, Kercher, M.A, Pace, H.C, Lu, P. | Deposit date: | 1996-02-17 | Release date: | 1996-07-11 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Crystal structure of the lactose operon repressor and its complexes with DNA and inducer. Science, 271, 1996
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1LBG
| LACTOSE OPERON REPRESSOR BOUND TO 21-BASE PAIR SYMMETRIC OPERATOR DNA, ALPHA CARBONS ONLY | Descriptor: | DNA (5'-D(*GP*AP*AP*TP*TP*GP*TP*GP*AP*GP*CP*GP*CP*TP*CP*AP*CP*AP*AP*TP*T)-3'), PROTEIN (LACTOSE OPERON REPRESSOR) | Authors: | Lewis, M, Chang, G, Horton, N.C, Kercher, M.A, Pace, H.C, Lu, P. | Deposit date: | 1996-01-03 | Release date: | 1996-02-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (4.8 Å) | Cite: | Crystal structure of the lactose operon repressor and its complexes with DNA and inducer. Science, 271, 1996
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1LBI
| LAC REPRESSOR | Descriptor: | LAC REPRESSOR | Authors: | Lewis, M, Chang, G, Horton, N.C, Kercher, M.A, Pace, H.C, Lu, P. | Deposit date: | 1996-02-17 | Release date: | 1996-07-11 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of the lactose operon repressor and its complexes with DNA and inducer. Science, 271, 1996
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2FJR
| Crystal Structure of Bacteriophage 186 | Descriptor: | Repressor protein CI | Authors: | Lewis, M. | Deposit date: | 2006-01-03 | Release date: | 2006-06-13 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | The structural basis of cooperative regulation at an alternate genetic switch Mol.Cell, 21, 2006
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2FKD
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1EFA
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1LRP
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1AFS
| RECOMBINANT RAT LIVER 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE (3-ALPHA-HSD) COMPLEXED WITH NADP AND TESTOSTERONE | Descriptor: | 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, TESTOSTERONE | Authors: | Bennett, M.J, Albert, R.H, Jez, J.M, Ma, H, Penning, T.M, Lewis, M. | Deposit date: | 1997-03-13 | Release date: | 1997-10-08 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Steroid recognition and regulation of hormone action: crystal structure of testosterone and NADP+ bound to 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase. Structure, 5, 1997
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1LWI
| 3-ALPHA-HYDROXYSTEROID/DIHYDRODIOL DEHYDROGENASE FROM RATTUS NORVEGICUS | Descriptor: | 3-ALPHA-HYDROXYSTEROID/DIHYDRODIOL DEHYDROGENASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Bennett, M.J, Schlegel, B.P, Jez, J.M, Penning, T.M, Lewis, M. | Deposit date: | 1996-02-24 | Release date: | 1996-12-07 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure of 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase complexed with NADP+. Biochemistry, 35, 1996
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1RAL
| THREE-DIMENSIONAL STRUCTURE OF RAT LIVER 3ALPHA-HYDROXYSTEROID(SLASH)DIHYDRODIOL DEHYDROGENASE: A MEMBER OF THE ALDO-KETO REDUCTASE SUPERFAMILY | Descriptor: | 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE | Authors: | Hoog, S.S, Pawlowski, J.E, Alzari, P.M, Penning, T.M, Lewis, M. | Deposit date: | 1994-02-04 | Release date: | 1994-04-30 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Three-dimensional structure of rat liver 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase: a member of the aldo-keto reductase superfamily. Proc.Natl.Acad.Sci.USA, 91, 1994
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2PE5
| Crystal Structure of the Lac Repressor bound to ONPG in repressed state | Descriptor: | 2-nitrophenyl beta-D-galactopyranoside, DNA (5'-D(*DAP*DAP*DTP*DTP*DGP*DTP*DGP*DAP*DGP*DCP*DGP*DCP*DTP*DCP*DAP*DCP*DAP*DAP*DTP*DT)-3'), Lactose operon repressor | Authors: | Daber, R, Stayrook, S.E, Rosenberg, A, Lewis, M. | Deposit date: | 2007-04-02 | Release date: | 2008-03-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structural analysis of lac repressor bound to allosteric effectors J.Mol.Biol., 370, 2007
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2YNN
| yeast betaprime COP 1-304 with KTKTN motif | Descriptor: | COATOMER SUBUNIT BETA', KTKTN MOTIF, SULFATE ION | Authors: | Jackson, L.P, Lewis, M, Kent, H.M, Edeling, M.A, Evans, P.R, Duden, R, Owen, D.J. | Deposit date: | 2012-10-17 | Release date: | 2012-12-12 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.782 Å) | Cite: | Molecular Basis for Recognition of Dilysine Trafficking Motifs by Copi. Dev.Cell, 23, 2012
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3BDN
| Crystal Structure of the Lambda Repressor | Descriptor: | DNA (5'-D(*DAP*DAP*DTP*DAP*DCP*DCP*DAP*DCP*DTP*DGP*DGP*DCP*DGP*DGP*DTP*DGP*DAP*DTP*DAP*DT)-3'), DNA (5'-D(*DTP*DAP*DTP*DAP*DTP*DCP*DAP*DCP*DCP*DGP*DCP*DCP*DAP*DGP*DTP*DGP*DGP*DTP*DAP*DT)-3'), Lambda Repressor | Authors: | Stayrook, S.E, Jaru-Ampornpan, P, Hochschild, A, Lewis, M. | Deposit date: | 2007-11-15 | Release date: | 2008-04-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3.909 Å) | Cite: | Crystal structure of the lambda repressor and a model for pairwise cooperative operator binding Nature, 452, 2008
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1F39
| CRYSTAL STRUCTURE OF THE LAMBDA REPRESSOR C-TERMINAL DOMAIN | Descriptor: | REPRESSOR PROTEIN CI | Authors: | Bell, C.E, Frescura, P, Hochschild, A, Lewis, M. | Deposit date: | 2000-06-01 | Release date: | 2000-07-26 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of the lambda repressor C-terminal domain provides a model for cooperative operator binding. Cell(Cambridge,Mass.), 101, 2000
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1KCA
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1JYE
| Structure of a Dimeric Lac Repressor with C-terminal Deletion and K84L Substitution | Descriptor: | GLYCEROL, Lactose Operon Repressor | Authors: | Bell, C.E, Barry, J, Matthews, K.S, Lewis, M. | Deposit date: | 2001-09-12 | Release date: | 2001-10-18 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure of a variant of lac repressor with increased thermostability and decreased affinity for operator. J.Mol.Biol., 313, 2001
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1M3W
| Crystal Structure of a Molecular Maquette Scaffold | Descriptor: | H10H24, MERCURY (II) ION | Authors: | Huang, S.S, Gibney, B.R, Stayrook, S.E, Dutton, P.L, Lewis, M. | Deposit date: | 2002-07-01 | Release date: | 2003-02-18 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | X-ray Structure of a Maquette Scaffold J.Mol.Biol., 326, 2003
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1JWL
| Structure of the Dimeric lac Repressor/Operator O1/ONPF Complex | Descriptor: | 2-nitrophenyl beta-D-fucopyranoside, 5'-D(*AP*GP*AP*AP*T*TP*GP*TP*GP*AP*GP*CP*GP*GP*AP*TP*AP*AP*CP*AP*AP*TP*T)-3', 5'-D(*TP*AP*AP*TP*TP*GP*TP*TP*AP*TP*CP*CP*GP*CP*TP*CP*AP*CP*AP*AP*TP*TP*C)-3', ... | Authors: | Bell, C.E, Lewis, M. | Deposit date: | 2001-09-04 | Release date: | 2001-10-05 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Crystallographic analysis of Lac repressor bound to natural operator O1. J.Mol.Biol., 312, 2001
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1JYF
| Structure of the Dimeric Lac Repressor with an 11-residue C-terminal Deletion. | Descriptor: | GLYCEROL, Lactose Operon Repressor | Authors: | Bell, C.E, Barry, J, Matthews, K.S, Lewis, M. | Deposit date: | 2001-09-12 | Release date: | 2001-10-18 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure of a variant of lac repressor with increased thermostability and decreased affinity for operator. J.Mol.Biol., 313, 2001
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1IHI
| Crystal Structure of Human Type III 3-alpha-Hydroxysteroid Dehydrogenase/Bile Acid Binding Protein (AKR1C2) Complexed with NADP+ and Ursodeoxycholate | Descriptor: | 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE, ISO-URSODEOXYCHOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Jin, Y, Stayrook, S.E, Albert, R.H, Palackal, N.T, Penning, T.M, Lewis, M. | Deposit date: | 2001-04-19 | Release date: | 2001-10-03 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structure of human type III 3alpha-hydroxysteroid dehydrogenase/bile acid binding protein complexed with NADP(+) and ursodeoxycholate. Biochemistry, 40, 2001
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2YNO
| yeast betaprime COP 1-304H6 | Descriptor: | COATOMER SUBUNIT BETA', POLY ALA | Authors: | Jackson, L.P, Lewis, M, Kent, H.M, Edeling, M.A, Evans, P.R, Duden, R, Owen, D.J. | Deposit date: | 2012-10-17 | Release date: | 2012-12-12 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Molecular Basis for Recognition of Dilysine Trafficking Motifs by Copi. Dev.Cell, 23, 2012
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2YNP
| yeast betaprime COP 1-604 with KTKTN motif | Descriptor: | COATOMER SUBUNIT BETA', KTKTN MOTIF | Authors: | Jackson, L.P, Lewis, M, Kent, H.M, Edeling, M.A, Evans, P.R, Duden, R, Owen, D.J. | Deposit date: | 2012-10-17 | Release date: | 2012-12-12 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.962 Å) | Cite: | Molecular Basis for Recognition of Dilysine Trafficking Motifs by Copi. Dev.Cell, 23, 2012
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4BV4
| Structure and allostery in Toll-Spatzle recognition | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEIN SPAETZLE C-106, PROTEIN TOLL, ... | Authors: | Lewis, M.F, Arnot, C.J, Beeston, H, McCoy, A, Ashcroft, A.E, Gay, N.J, Gangloff, M. | Deposit date: | 2013-06-24 | Release date: | 2013-12-04 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Cytokine Spatzle Binds to the Drosophila Immunoreceptor Toll with a Neurotrophin-Like Specificity and Couples Receptor Activation. Proc.Natl.Acad.Sci.USA, 110, 2013
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3MO7
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1AAQ
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