1D5R
 
 | | Crystal Structure of the PTEN Tumor Suppressor | | 分子名称: | L(+)-TARTARIC ACID, PHOSPHOINOSITIDE PHOSPHATASE PTEN | | 著者 | Lee, J.O, Yang, H, Georgescu, M.-M, Di Cristofano, A, Pavletich, N.P. | | 登録日 | 1999-10-11 | | 公開日 | 1999-11-04 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association.
Cell(Cambridge,Mass.), 99, 1999
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1GUX
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2Z82
 | | Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide | | 分子名称: | (2R)-3-{[(2R)-2-AMINO-3-HYDROXYPROPYL]THIO}PROPANE-1,2-DIYL DIHEXADECANOATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Lee, J.O, Jin, M.S, Kim, S.E, Heo, J.Y. | | 登録日 | 2007-08-30 | | 公開日 | 2007-10-02 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal Structure of the TLR1-TLR2 Heterodimer Induced by Binding of a Tri-Acylated Lipopeptide
Cell(Cambridge,Mass.), 130, 2007
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2Z80
 | | Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Toll-like receptor 2, Variable lymphocyte receptor B | | 著者 | Lee, J.O, Jin, M.S, Kim, S.E, Heo, J.Y. | | 登録日 | 2007-08-30 | | 公開日 | 2007-09-25 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal Structure of the TLR1-TLR2 Heterodimer Induced by Binding of a Tri-Acylated Lipopeptide
Cell(Cambridge,Mass.), 130, 2007
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2Z81
 | | Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide | | 分子名称: | (2R)-3-{[(2S)-3-HYDROXY-2-(PALMITOYLAMINO)PROPYL]THIO}PROPANE-1,2-DIYL DIHEXADECANOATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Toll-like receptor 2, ... | | 著者 | Lee, J.O, Jin, M.S, Kim, S.E, Heo, J.Y. | | 登録日 | 2007-08-30 | | 公開日 | 2007-10-02 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal Structure of the TLR1-TLR2 Heterodimer Induced by Binding of a Tri-Acylated Lipopeptide
Cell(Cambridge,Mass.), 130, 2007
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2Z7X
 | | Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide | | 分子名称: | (2S)-3-hydroxypropane-1,2-diyl dihexadecanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, PALMITIC ACID, ... | | 著者 | Lee, J.O, Jin, M.S, Kim, S.E, Heo, J.Y. | | 登録日 | 2007-08-29 | | 公開日 | 2007-10-02 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal Structure of the TLR1-TLR2 Heterodimer Induced by Binding of a Tri-Acylated Lipopeptide
Cell(Cambridge,Mass.), 130, 2007
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6K65
 | | Application of anti-helix antibodies in protein structure determination (9014-1P4B) | | 分子名称: | 1P4B variable heavy chain, 1P4B variable light chain, Immunoglobulin G-binding protein A | | 著者 | Lee, J.O, Jin, M.S, Kim, J.W, Kim, S, Lee, H, Cho, G.Y. | | 登録日 | 2019-06-01 | | 公開日 | 2019-08-14 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Application of antihelix antibodies in protein structure determination.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6K6B
 | | Application of anti-helix antibodies in protein structure determination (8496-3LRH) | | 分子名称: | 3LRH intrabody, Protein A | | 著者 | Lee, J.O, Jin, M.S, Kim, J.W, Kim, S, Lee, H, Cho, G.Y. | | 登録日 | 2019-06-02 | | 公開日 | 2019-08-14 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | | 主引用文献 | Application of antihelix antibodies in protein structure determination.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6K3M
 | | Application of anti-helix antibodies in protein structure determination (8189-3LRH) | | 分子名称: | 3LRH intrabody, SpA IgG-binding domain protein,Protein A | | 著者 | Lee, J.O, Jin, M.S, Kim, J.W, Kim, S, Lee, H, Cho, G.Y. | | 登録日 | 2019-05-20 | | 公開日 | 2019-08-14 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Application of antihelix antibodies in protein structure determination.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6K67
 | | Application of anti-helix antibodies in protein structure determination (9011-3LRH) | | 分子名称: | 3LRH introbody, CALCIUM ION, Engineered calmodulin | | 著者 | Lee, J.O, Jin, M.S, Kim, J.W, Kim, S, Lee, H, Cho, G.Y. | | 登録日 | 2019-06-01 | | 公開日 | 2019-08-14 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Application of antihelix antibodies in protein structure determination.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6K64
 | | Application of anti-helix antibodies in protein structure determination (8188-3LRH) | | 分子名称: | 3LRH intrabody, Protein A | | 著者 | Lee, J.O, Jin, M.S, Kim, J.W, Kim, S, Lee, H, Cho, G.Y. | | 登録日 | 2019-06-01 | | 公開日 | 2019-08-14 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.933 Å) | | 主引用文献 | Application of antihelix antibodies in protein structure determination.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6K6A
 | | Application of anti-helix antibodies in protein structure determination (8188cys-3LRHcys) | | 分子名称: | 3LRH intrabody, Engineered Protein A | | 著者 | Lee, J.O, Jin, M.S, Kim, J.W, Kim, S, Lee, H, Cho, G.Y. | | 登録日 | 2019-06-02 | | 公開日 | 2019-08-14 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Application of antihelix antibodies in protein structure determination.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6K68
 | | Application of anti-helix antibodies in protein structure determination (8420-3MNZ) | | 分子名称: | 3MNZ Variable heavy chain, 3MNZ Variable light chain, Protein A | | 著者 | Lee, J.O, Jin, M.S, Kim, J.W, Kim, S, Lee, H, Cho, G.Y. | | 登録日 | 2019-06-01 | | 公開日 | 2019-08-14 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Application of antihelix antibodies in protein structure determination.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6K69
 | | Application of anti-helix antibodies in protein structure determination (9213-3LRH) | | 分子名称: | 3LRH intrabody, Engineered T4 lysozyme | | 著者 | Lee, J.O, Jin, M.S, Kim, J.W, Kim, S, Lee, H, Cho, G.Y. | | 登録日 | 2019-06-01 | | 公開日 | 2019-08-14 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.401 Å) | | 主引用文献 | Application of antihelix antibodies in protein structure determination.
Proc.Natl.Acad.Sci.USA, 116, 2019
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2O6S
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2O6Q
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2O6R
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3Q8W
 | | A b-aminoacyl containing thiazolidine derivative and DPPIV complex | | 分子名称: | Dipeptidyl peptidase 4, N-(4-{[({(2R)-3-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]-1,3-thiazolidin-2-yl}carbonyl)amino]methyl}phenyl)-D-valine | | 著者 | Lee, J.O, Song, D.H. | | 登録日 | 2011-01-07 | | 公開日 | 2011-03-16 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (3.64 Å) | | 主引用文献 | Discovery of b-aminoacyl containing thiazolidine derivatives as potent and selective dipeptidyl peptidase IV inhibitors
To be Published
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8J26
 | | CryoEM structure of SARS CoV-2 RBD and Aptamer complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, AM032-4, AM047-6, ... | | 著者 | Rahman, M.S, Jang, S.K, Lee, J.O. | | 登録日 | 2023-04-14 | | 公開日 | 2023-06-21 | | 最終更新日 | 2023-07-12 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structure-Guided Development of Bivalent Aptamers Blocking SARS-CoV-2 Infection.
Molecules, 28, 2023
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8J1Q
 | | CryoEM structure of SARS CoV-2 RBD and Aptamer complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, AM032-0, AM047-0, ... | | 著者 | Rahman, M.S, Jang, S.K, Lee, J.O. | | 登録日 | 2023-04-13 | | 公開日 | 2023-06-21 | | 最終更新日 | 2023-07-12 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structure-Guided Development of Bivalent Aptamers Blocking SARS-CoV-2 Infection.
Molecules, 28, 2023
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1BI8
 | | MECHANISM OF G1 CYCLIN DEPENDENT KINASE INHIBITION FROM THE STRUCTURES CDK6-P19INK4D INHIBITOR COMPLEX | | 分子名称: | CYCLIN-DEPENDENT KINASE 6, CYCLIN-DEPENDENT KINASE INHIBITOR | | 著者 | Russo, A.A, Tong, L, Lee, J.O, Jeffrey, P.D, Pavletich, N.P. | | 登録日 | 1998-06-22 | | 公開日 | 1999-01-13 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural basis for inhibition of the cyclin-dependent kinase Cdk6 by the tumour suppressor p16INK4a.
Nature, 395, 1998
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1BI7
 | | MECHANISM OF G1 CYCLIN DEPENDENT KINASE INHIBITION FROM THE STRUCTURE OF THE CDK6-P16INK4A TUMOR SUPPRESSOR COMPLEX | | 分子名称: | CYCLIN-DEPENDENT KINASE 6, MULTIPLE TUMOR SUPPRESSOR | | 著者 | Russo, A.A, Tong, L, Lee, J.O, Jeffrey, P.D, Pavletich, N.P. | | 登録日 | 1998-06-22 | | 公開日 | 1999-01-13 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Structural basis for inhibition of the cyclin-dependent kinase Cdk6 by the tumour suppressor p16INK4a.
Nature, 395, 1998
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5X3F
 | | Crystal structure of the YgjG-Protein A-Zpa963-PKA catalytic domain | | 分子名称: | Putrescine aminotransferase,Immunoglobulin G-binding protein A, Zpa963,cAMP-dependent protein kinase catalytic subunit alpha | | 著者 | Youn, S.J, Kwon, N.Y, Lee, J.H, Kim, J.H, Lee, H, Lee, J.O. | | 登録日 | 2017-02-05 | | 公開日 | 2017-06-28 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.38 Å) | | 主引用文献 | Construction of novel repeat proteins with rigid and predictable structures using a shared helix method.
Sci Rep, 7, 2017
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7WVF
 | | ectoTLR3-mAb12-poly(I:C) complex | | 分子名称: | RNA (46-MER), Toll-like receptor 3, mAb12 | | 著者 | Lim, C.S, Jang, Y.H, Lee, G.Y, Han, G.M, Lee, J.O. | | 登録日 | 2022-02-10 | | 公開日 | 2022-11-16 | | 最終更新日 | 2022-12-07 | | 実験手法 | ELECTRON MICROSCOPY (3.91 Å) | | 主引用文献 | TLR3 forms a highly organized cluster when bound to a poly(I:C) RNA ligand.
Nat Commun, 13, 2022
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7WVE
 | | CT-mut (D523K,D524K,E527K) TLR3-poly(I:C) complex | | 分子名称: | RNA (46-MER), Toll-like receptor 3 | | 著者 | Lim, C.S, Jang, Y.H, Lee, G.Y, Han, G.M, Lee, J.O. | | 登録日 | 2022-02-10 | | 公開日 | 2022-11-16 | | 最終更新日 | 2022-12-07 | | 実験手法 | ELECTRON MICROSCOPY (3.11 Å) | | 主引用文献 | TLR3 forms a highly organized cluster when bound to a poly(I:C) RNA ligand.
Nat Commun, 13, 2022
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