2Z64
 
 | | Crystal structure of mouse TLR4 and mouse MD-2 complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Lymphocyte antigen 96, ... | | Authors: | Lee, J.-O, Kim, H.M, Park, B.S. | | Deposit date: | 2007-07-22 | | Release date: | 2007-09-18 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.84 Å) | | Cite: | Crystal Structure of the TLR4-MD-2 Complex with Bound Endotoxin Antagonist Eritoran
Cell(Cambridge,Mass.), 130, 2007
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2Z62
 | | Crystal structure of the TV3 hybrid of human TLR4 and hagfish VLRB.61 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Toll-like receptor 4, ... | | Authors: | Lee, J.-O, Kim, H.M, Park, B.S. | | Deposit date: | 2007-07-22 | | Release date: | 2007-09-18 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Crystal Structure of the TLR4-MD-2 Complex with Bound Endotoxin Antagonist Eritoran
Cell(Cambridge,Mass.), 130, 2007
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3QD6
 | | Crystal structure of the CD40 and CD154 (CD40L) complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CD40 ligand, Tumor necrosis factor receptor superfamily member 5 | | Authors: | Lee, J.-O, Kim, Y.J, Song, D.H, Kim, H.M, Park, B.S. | | Deposit date: | 2011-01-18 | | Release date: | 2011-02-02 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Crystallographic and mutational analysis of the CD40-CD154 complex and its implications for receptor activation
J.Biol.Chem., 286, 2011
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2Z66
 | | Crystal structure of the VT3 hybrid of human TLR4 and hagfish VLRB.61 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, Variable lymphocyte receptor B, ... | | Authors: | Lee, J.-O, Kim, H.M, Park, B.S. | | Deposit date: | 2007-07-22 | | Release date: | 2007-09-18 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal Structure of the TLR4-MD-2 Complex with Bound Endotoxin Antagonist Eritoran
Cell(Cambridge,Mass.), 130, 2007
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2Z65
 | | Crystal structure of the human TLR4 TV3 hybrid-MD-2-Eritoran complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-O-DECYL-2-DEOXY-6-O-{2-DEOXY-3-O-[(3R)-3-METHOXYDECYL]-6-O-METHYL-2-[(11Z)-OCTADEC-11-ENOYLAMINO]-4-O-PHOSPHONO-BETA-D-GLUCOPYRANOSYL}-2-[(3-OXOTETRADECANOYL)AMINO]-1-O-PHOSPHONO-ALPHA-D-GLUCOPYRANOSE, Lymphocyte antigen 96, ... | | Authors: | Lee, J.-O, Kim, H.M, Park, B.S. | | Deposit date: | 2007-07-22 | | Release date: | 2007-09-18 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal Structure of the TLR4-MD-2 Complex with Bound Endotoxin Antagonist Eritoran
Cell(Cambridge,Mass.), 130, 2007
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1IDO
 | | I-DOMAIN FROM INTEGRIN CR3, MG2+ BOUND | | Descriptor: | INTEGRIN, MAGNESIUM ION | | Authors: | Lee, J.-O, Liddington, R. | | Deposit date: | 1996-03-12 | | Release date: | 1996-08-01 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Crystal structure of the A domain from the alpha subunit of integrin CR3 (CD11b/CD18).
Cell(Cambridge,Mass.), 80, 1995
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4V46
 | | Crystal structure of the BAFF-BAFF-R complex | | Descriptor: | MAGNESIUM ION, Tumor necrosis factor ligand superfamily member 13B, Tumor necrosis factor receptor superfamily member 13C | | Authors: | Kim, H.M, Yu, K.S, Lee, M.E, Shin, D.R, Kim, Y.S, Paik, S.G, Yoo, O.J, Lee, H, Lee, J.-O. | | Deposit date: | 2003-03-23 | | Release date: | 2014-07-09 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Crystal structure of the BAFF-BAFF-R complex and its implications for receptor activation
NAT.STRUCT.BIOL., 10, 2003
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9LSK
 | | Cryo-EM structure of the Klebsiella pneumoniae CitS (citrate-bound occluded state) | | Descriptor: | CITRIC ACID, Citrate/sodium symporter, PALMITIC ACID | | Authors: | Kim, S, Kim, J.W, Park, J.G, Lee, S.S, Choi, S.H, Lee, J.-O, Jin, M.S. | | Deposit date: | 2025-02-04 | | Release date: | 2025-03-12 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Disulfide-stabilized diabodies enable near-atomic cryo-EM imaging of small proteins: A case study of the bacterial Na+/citrate symporter CitS
To Be Published
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9LSJ
 | | Cryo-EM structure of the G15C-R66C and T83C-T83C diabody complex (CitS-diabody #7-TLR3) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CITRIC ACID, ... | | Authors: | Kim, S, Kim, J.W, Park, J.G, Lee, S.S, Choi, S.H, Lee, J.-O, Jin, M.S. | | Deposit date: | 2025-02-04 | | Release date: | 2025-03-12 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Disulfide-stabilized diabodies enable near-atomic cryo-EM imaging of small proteins: A case study of the bacterial Na+/citrate symporter CitS
To Be Published
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9LSI
 | | Cryo-EM structure of the S82C-S82C diabody complex (CitS-diabody #2-TLR3) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Kim, S, Kim, J.W, Park, J.G, Lee, S.S, Choi, S.H, Lee, J.-O, Jin, M.S. | | Deposit date: | 2025-02-04 | | Release date: | 2025-03-12 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Disulfide-stabilized diabodies enable near-atomic cryo-EM imaging of small proteins: A case study of the bacterial Na+/citrate symporter CitS
To Be Published
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9LSH
 | | Cryo-EM structure of the wild-type diabody complex (CitS-diabody #1-TLR3) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Kim, S, Kim, J.W, Park, J.G, Lee, S.S, Choi, S.H, Lee, J.-O, Jin, M.S. | | Deposit date: | 2025-02-04 | | Release date: | 2025-03-12 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Disulfide-stabilized diabodies enable near-atomic cryo-EM imaging of small proteins: A case study of the bacterial Na+/citrate symporter CitS
To Be Published
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1UDT
 | | Crystal structure of Human Phosphodiesterase 5 complexed with Sildenafil(Viagra) | | Descriptor: | 5-{2-ETHOXY-5-[(4-METHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}-1-METHYL-3-PROPYL-1H,6H,7H-PYRAZOLO[4,3-D]PYRIMIDIN-7-ONE, MAGNESIUM ION, ZINC ION, ... | | Authors: | Sung, B.-J, Lee, J.I, Heo, Y.-S, Kim, J.H, Moon, J, Yoon, J.M, Hyun, Y.-L, Kim, E, Eum, S.J, Lee, T.G, Cho, J.M, Park, S.-Y, Lee, J.-O, Jeon, Y.H, Hwang, K.Y, Ro, S. | | Deposit date: | 2003-05-06 | | Release date: | 2004-05-11 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure of the catalytic domain of human phosphodiesterase 5 with bound drug molecules
Nature, 425, 2003
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1UDU
 | | Crystal structure of Human Phosphodiesterase 5 complexed with tadalafil(Cialis) | | Descriptor: | 6-BENZO[1,3]DIOXOL-5-YL-2-METHYL-2,3,6,7,12,12A-HEXAHYDRO-PYRAZINO[1',2':1,6]PYRIDO[3,4-B]INDOLE-1,4-DIONE, MAGNESIUM ION, ZINC ION, ... | | Authors: | Sung, B.-J, Lee, J.I, Heo, Y.-S, Kim, J.H, Moon, J, Yoon, J.M, Hyun, Y.-L, Kim, E, Eum, S.J, Lee, T.G, Cho, J.M, Park, S.-Y, Lee, J.-O, Jeon, Y.H, Hwang, K.Y, Ro, S. | | Deposit date: | 2003-05-06 | | Release date: | 2004-05-11 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.83 Å) | | Cite: | Structure of the catalytic domain of human phosphodiesterase 5 with bound drug molecules
Nature, 425, 2003
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1UHO
 | | Crystal structure of Human Phosphodiesterase 5 complexed with Vardenafil(Levitra) | | Descriptor: | 2-{2-ETHOXY-5-[(4-ETHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}-5-METHYL-7-PROPYLIMIDAZO[5,1-F][1,2,4]TRIAZIN-4(1H)-ONE, MAGNESIUM ION, ZINC ION, ... | | Authors: | Sung, B.-J, Lee, J.I, Heo, Y.-S, Kim, J.H, Moon, J, Yoon, J.M, Hyun, Y.-L, Kim, E, Eum, S.J, Lee, T.G, Cho, J.M, Park, S.-Y, Lee, J.-O, Jeon, Y.H, Hwang, K.Y, Ro, S. | | Deposit date: | 2003-07-09 | | Release date: | 2004-07-09 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure of the catalytic domain of human phosphodiesterase 5 with bound drug molecules
Nature, 425, 2003
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1MKD
 | | crystal structure of PDE4D catalytic domain and zardaverine complex | | Descriptor: | 6-(4-DIFLUOROMETHOXY-3-METHOXY-PHENYL)-2H-PYRIDAZIN-3-ONE, MAGNESIUM ION, Phosphodiesterase 4D, ... | | Authors: | Lee, M.E, Markowitz, J, Lee, J.-O, Lee, H. | | Deposit date: | 2002-08-29 | | Release date: | 2003-03-01 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Crystal structure of phosphodiesterase 4D and inhibitor complex
FEBS LETT., 530, 2002
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1J36
 | | Crystal Structure of Drosophila AnCE | | Descriptor: | ZINC ION, [N2-[(S)-1-CARBOXY-3-PHENYLPROPYL]-L-LYSYL-L-PROLINE, angiotensin converting enzyme | | Authors: | Kim, H.M, Shin, D.R, Yoo, O.J, Lee, H, Lee, J.-O. | | Deposit date: | 2003-01-20 | | Release date: | 2003-07-20 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure of Drosophila angiotensin I-converting enzyme bound to captopril and lisinopril
Febs Lett., 538, 2003
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1J37
 | | Crystal Structure of Drosophila AnCE | | Descriptor: | L-CAPTOPRIL, ZINC ION, angiotensin converting enzyme | | Authors: | Kim, H.M, Shin, D.R, Yoo, O.J, Lee, H, Lee, J.-O. | | Deposit date: | 2003-01-20 | | Release date: | 2003-07-20 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure of Drosophila angiotensin I-converting enzyme bound to captopril and lisinopril
Febs Lett., 538, 2003
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1J38
 | | Crystal Structure of Drosophila AnCE | | Descriptor: | ZINC ION, angiotensin converting enzyme | | Authors: | Kim, H.M, Shin, D.R, Lee, H, Lee, J.-O. | | Deposit date: | 2003-01-20 | | Release date: | 2003-07-20 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal structure of Drosophila angiotensin I-converting enzyme bound to captopril and lisinopril
Febs Lett., 538, 2003
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3FXI
 | | Crystal structure of the human TLR4-human MD-2-E.coli LPS Ra complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-HYDROXY-TETRADECANOIC ACID, ... | | Authors: | Park, B.S, Song, D.H, Kim, H.M, Lee, J.-O. | | Deposit date: | 2009-01-21 | | Release date: | 2009-03-03 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex
Nature, 458, 2009
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7XCB
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2Z63
 | | Crystal structure of the TV8 hybrid of human TLR4 and hagfish VLRB.61 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Toll-like receptor 4, ... | | Authors: | Kim, H.M, Park, B.S, Lee, J.-O. | | Deposit date: | 2007-07-22 | | Release date: | 2007-09-18 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal Structure of the TLR4-MD-2 Complex with Bound Endotoxin Antagonist Eritoran
Cell(Cambridge,Mass.), 130, 2007
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3A7C
 | | Crystal structure of TLR2-PE-DTPA complex | | Descriptor: | (10S,13R)-3-{2-[{2-[bis(carboxymethyl)amino]ethyl}(carboxymethyl)amino]ethyl}-10-hydroxy-5,16-dioxo-13-(tetradecanoyloxy)-9,11,15-trioxa-3,6-diaza-10-phosphanonacosan-1-oic acid 10-oxide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Kang, J.Y, Jin, M.S, Lee, J.-O. | | Deposit date: | 2009-09-20 | | Release date: | 2009-11-24 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Recognition of lipopeptide patterns by Toll-like receptor 2-Toll-like receptor 6 heterodimer
Immunity, 31, 2009
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3A79
 | | Crystal structure of TLR2-TLR6-Pam2CSK4 complex | | Descriptor: | (2S)-propane-1,2-diyl dihexadecanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Kang, J.Y, Jin, M.S, Lee, J.-O. | | Deposit date: | 2009-09-20 | | Release date: | 2009-11-24 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Recognition of lipopeptide patterns by Toll-like receptor 2-Toll-like receptor 6 heterodimer
Immunity, 31, 2009
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3A7B
 | | Crystal structure of TLR2-Streptococcus Pneumoniae lipoteichoic acid complex | | Descriptor: | (2S)-1-({3-O-[2-(acetylamino)-4-amino-2,4,6-trideoxy-beta-D-galactopyranosyl]-alpha-D-glucopyranosyl}oxy)-3-(heptanoyloxy)propan-2-yl (7Z)-pentadec-7-enoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Kang, J.Y, Jin, M.S, Lee, J.-O. | | Deposit date: | 2009-09-20 | | Release date: | 2009-11-24 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.53 Å) | | Cite: | Recognition of lipopeptide patterns by Toll-like receptor 2-Toll-like receptor 6 heterodimer
Immunity, 31, 2009
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6L0Y
 | | Structure of dsRNA with G-U wobble base pairs | | Descriptor: | RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*GP*CP*GP*UP*UP*UP*GP*CP*C)-3') | | Authors: | Kim, K.-H, Hwang, J, Kim, J.H, Son, K.-P, Jang, Y, Kim, M, Kang, S.-J, Lee, J.-O, Choi, B.-S. | | Deposit date: | 2019-09-27 | | Release date: | 2020-09-30 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structure of dsRNA with G-U wobble base pairs
To Be Published
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