3A79

Crystal structure of TLR2-TLR6-Pam2CSK4 complex

Summary for 3A79

Entry DOI	10.2210/pdb3a79/pdb
Related	3A7B 3A7C
Descriptor	Toll-like receptor 2, Variable lymphocyte receptor B, Toll-like receptor 6, Variable lymphocyte receptor B, Pam2CSK4, ... (7 entities in total)
Functional Keywords	toll-like receptor, diacyl lipopeptide, innate immunity, leucine rich repeat, cell membrane, cytoplasmic vesicle, disulfide bond, glycoprotein, immune response, inflammatory response, leucine-rich repeat, membrane, receptor, transmembrane, phosphoprotein, immune system
Biological source	Mus musculus (mouse, Inshore hagfish) More
Total number of polymer chains	3
Total formula weight	134737.60
Authors	Kang, J.Y.,Jin, M.S.,Lee, J.-O. (deposition date: 2009-09-20, release date: 2009-11-24, Last modification date: 2023-11-01)
Primary citation	Kang, J.Y.,Nan, X.,Jin, M.S.,Youn, S.-J.,Ryu, Y.H.,Mah, S.,Han, S.H.,Lee, H.,Paik, S.-G.,Lee, J.-O. Recognition of lipopeptide patterns by Toll-like receptor 2-Toll-like receptor 6 heterodimer Immunity, 31:873-884, 2009 Cited by PubMed: 19931471 DOI: 10.1016/j.immuni.2009.09.018 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation