4MVD
 
 | | Crystal Structure of a Mammalian Cytidylyltransferase | | Descriptor: | Choline-phosphate cytidylyltransferase A, [2-CYTIDYLATE-O'-PHOSPHONYLOXYL]-ETHYL-TRIMETHYL-AMMONIUM | | Authors: | Lee, J, Cornell, R.B. | | Deposit date: | 2013-09-23 | | Release date: | 2013-12-11 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (8 Å) | | Cite: | Structural Basis for Autoinhibition of CTP:Phosphocholine Cytidylyltransferase (CCT), the Regulatory Enzyme in Phosphatidylcholine Synthesis, by Its Membrane-binding Amphipathic Helix.
J.Biol.Chem., 289, 2014
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2R64
 | | Crystal structure of a 3-aminoindazole compound with CDK2 | | Descriptor: | Cell division protein kinase 2, N-[5-(1,1-DIOXIDOISOTHIAZOLIDIN-2-YL)-1H-INDAZOL-3-YL]-2-(4-PIPERIDIN-1-YLPHENYL)ACETAMIDE | | Authors: | Lee, J, Choi, H, Kim, K.H, Jeong, S, Park, J.W, Baek, C.S, Lee, S.H. | | Deposit date: | 2007-09-05 | | Release date: | 2008-09-09 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Synthesis and biological evaluation of 3,5-diaminoindazoles as cyclin-dependent kinase inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
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5CRU
 | | Crystal structure of the Bro domain of HD-PTP | | Descriptor: | Tyrosine-protein phosphatase non-receptor type 23 | | Authors: | Lee, J, Ku, B, Kim, S.J. | | Deposit date: | 2015-07-23 | | Release date: | 2016-02-24 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural Study of the HD-PTP Bro1 Domain in a Complex with the Core Region of STAM2, a Subunit of ESCRT-0
Plos One, 11, 2016
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5CRV
 | | Crystal structure of the Bro domain of HD-PTP in a complex with the core region of STAM2 | | Descriptor: | GLYCEROL, Signal transducing adapter molecule 2, Tyrosine-protein phosphatase non-receptor type 23 | | Authors: | Lee, J, Ku, B, Kim, S.J. | | Deposit date: | 2015-07-23 | | Release date: | 2016-02-24 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.001 Å) | | Cite: | Structural Study of the HD-PTP Bro1 Domain in a Complex with the Core Region of STAM2, a Subunit of ESCRT-0
Plos One, 11, 2016
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2PLJ
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2QQS
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8T46
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8T4H
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8T4F
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8T4G
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8T4J
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8T4I
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8T4E
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2VLG
 | | KinA PAS-A domain, homodimer | | Descriptor: | ACETATE ION, CHLORIDE ION, SPORULATION KINASE A | | Authors: | Lee, J, Tomchick, D.R, Brautigam, C.A, Machius, M, Kort, R, Hellingwerf, K.J, Gardner, K.H. | | Deposit date: | 2008-01-14 | | Release date: | 2008-03-18 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Changes at the Kina Pas-A Dimerization Interface Influence Histidine Kinase Function.
Biochemistry, 47, 2008
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2QQR
 | | JMJD2A hybrid tudor domains | | Descriptor: | JmjC domain-containing histone demethylation protein 3A, SULFATE ION | | Authors: | Lee, J, Botuyan, M.V, Mer, G. | | Deposit date: | 2007-07-26 | | Release date: | 2007-12-11 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Distinct binding modes specify the recognition of methylated histones H3K4 and H4K20 by JMJD2A-tudor.
Nat.Struct.Mol.Biol., 15, 2008
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8U29
 | | Prefusion structure of the PRD-0038 spike glycoprotein ectodomain trimer | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PRD-0038 Spike glycoprotein, ... | | Authors: | Lee, J, Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | | Deposit date: | 2023-09-05 | | Release date: | 2023-12-06 | | Last modified: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Broad receptor tropism and immunogenicity of a clade 3 sarbecovirus.
Cell Host Microbe, 31, 2023
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3BAG
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3HL4
 | | Crystal structure of a mammalian CTP:phosphocholine cytidylyltransferase with CDP-choline | | Descriptor: | Choline-phosphate cytidylyltransferase A, FORMIC ACID, GLYCEROL, ... | | Authors: | Lee, J, Paetzel, M, Cornell, R.B. | | Deposit date: | 2009-05-26 | | Release date: | 2009-09-22 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal Structure of a mammalian CTP: Phosphocholine cytidylyltransferase catalytic domain reveals novel active site residues within a highly conserved nucleotidyl-transferase fold
J.Biol.Chem., 284, 2009
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2B02
 | | Crystal Structure of ARNT PAS-B Domain | | Descriptor: | Aryl hydrocarbon receptor nuclear translocator | | Authors: | Lee, J, Botuyan, M.V, Nomine, Y, Ohh, M, Thompson, J.R, Mer, G. | | Deposit date: | 2005-09-12 | | Release date: | 2006-10-24 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Crystal Structure and Binding Properties of ARNT PAS-B Heterodimerization Domain
To be Published
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2AQZ
 | | Crystal structure of FGF-1, S17T/N18T/G19 deletion mutant | | Descriptor: | Heparin-binding growth factor 1, SULFATE ION | | Authors: | Lee, J, Blaber, M. | | Deposit date: | 2005-08-18 | | Release date: | 2006-02-07 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Conversion of type I 4:6 to 3:5 beta-turn types in human acidic fibroblast growth factor: Effects upon structure, stability, folding, and mitogenic function.
Proteins, 62, 2006
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7Y7O
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9CL9
 | | WT 12C IM fraction, B-b3 with RluB bound | | Descriptor: | 23S rRNA, Large ribosomal subunit protein bL20, Large ribosomal subunit protein bL21, ... | | Authors: | Lee, J, Sheng, K, Williamson, J.R. | | Deposit date: | 2024-07-10 | | Release date: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (5.04 Å) | | Cite: | 50S ribosome assembly intermediates at low temperature reveal bound RluB
To Be Published
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8DRX
 | | Product structure of SARS-CoV-2 Mpro C145A mutant in complex with nsp10-nsp11 (C10) cut site sequence (form 2) | | Descriptor: | Fusion protein of 3C-like proteinase nsp5 and nsp10-nsp11 (C10) cut site, SODIUM ION | | Authors: | Lee, J, Kenward, C, Worrall, L.J, Vuckovic, M, Paetzel, M, Strynadka, N.C.J. | | Deposit date: | 2022-07-21 | | Release date: | 2022-09-21 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | X-ray crystallographic characterization of the SARS-CoV-2 main protease polyprotein cleavage sites essential for viral processing and maturation.
Nat Commun, 13, 2022
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8DRS
 | | Product structure of SARS-CoV-2 Mpro C145A mutant in complex with nsp6-nsp7 (C6) cut site sequence | | Descriptor: | 3C-like proteinase nsp5 | | Authors: | Lee, J, Kenward, C, Worrall, L.J, Vuckovic, M, Paetzel, M, Strynadka, N.C.J. | | Deposit date: | 2022-07-21 | | Release date: | 2022-09-21 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | X-ray crystallographic characterization of the SARS-CoV-2 main protease polyprotein cleavage sites essential for viral processing and maturation.
Nat Commun, 13, 2022
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8DRR
 | | Product structure of SARS-CoV-2 Mpro C145A mutant in complex with nsp4-nsp5 (C4) cut site sequence | | Descriptor: | 3C-like proteinase nsp5, SODIUM ION | | Authors: | Lee, J, Kenward, C, Worrall, L.J, Vuckovic, M, Paetzel, M, Strynadka, N.C.J. | | Deposit date: | 2022-07-21 | | Release date: | 2022-09-21 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | X-ray crystallographic characterization of the SARS-CoV-2 main protease polyprotein cleavage sites essential for viral processing and maturation.
Nat Commun, 13, 2022
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