2AQZ

Crystal structure of FGF-1, S17T/N18T/G19 deletion mutant

Summary for 2AQZ

• Entry DOI: 10.2210/pdb2aqz/pdb
• Related: 1JQZ
• Descriptor: Heparin-binding growth factor 1, SULFATE ION (3 entities in total)
• Functional Keywords: beta-trefoil, hormone-growth factor complex, hormone/growth factor
• Biological source: Homo sapiens (human)
• Cellular location: Secreted: P05230
• Total number of polymer chains: 2
• Total formula weight: 33357.51

Authors

Lee, J.,Blaber, M. (deposition date: 2005-08-18, release date: 2006-02-07, Last modification date: 2023-08-23)

• Primary citation: Lee, J.,Dubey, V.K.,Somasundaram, T.,Blaber, M.; Conversion of type I 4:6 to 3:5 beta-turn types in human acidic fibroblast growth factor: Effects upon structure, stability, folding, and mitogenic function.; Proteins, 62:686-697, 2006; PubMed: 16355415; DOI: 10.1002/prot.20808

Experimental method

X-RAY DIFFRACTION (1.85 Å)