2AQZ
Crystal structure of FGF-1, S17T/N18T/G19 deletion mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Heparin-binding growth factor 1 | polymer | 145 | 16630.7 | 2 | UniProt (P05230) Pfam (PF00167) | Homo sapiens (human) | HBGF-1, Acidic fibroblast growth factor, aFGF, Beta-endothelial cell growth factor, ECGF- beta |
| 2 | C (B) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 3 | D, E (A, B) | water | water | 18.0 | 277 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 140 (UniProt: P05230)
| PDB | External Database | Details |
|---|---|---|
| His 1 | - | expression tag |
| His 1 | - | expression tag |
| His 1 | - | expression tag |
| His 1 | - | expression tag |
| His 1 | - | expression tag |
| His 1 | - | expression tag |
| Thr 17 | Ser 32 | engineered mutation |
| Thr 18 | Asn 33 | engineered mutation |
| - | Gly 34 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 33261.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 96.1 | |
| All* | Total formula weight | 33357.5 |
