2AQZ

Crystal structure of FGF-1, S17T/N18T/G19 deletion mutant

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Heparin-binding growth factor 1	polymer	145	16630.7	2	UniProt (P05230) Pfam (PF00167) In PDB	Homo sapiens (human)	HBGF-1, Acidic fibroblast growth factor, aFGF, Beta-endothelial cell growth factor, ECGF- beta
2	B	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
3		water	water		18.0	277	Chemie (HOH)

Sequence modifications

A, B: 1 - 140 (UniProt: P05230)

PDB	External Database	Details
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
Thr 17	Ser 32	engineered mutation
Thr 18	Asn 33	engineered mutation
-	Gly 34	deletion

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	33261.4
Non-Polymers*	Number of molecules	1
	Total formula weight	96.1
All*	Total formula weight	33357.5

*Water molecules are not included.