6XQK
 
 | | Crystal structure of the D/D domain of PKA from S. cerevisiae | | 分子名称: | CHLORIDE ION, GLYCEROL, cAMP-dependent protein kinase regulatory subunit | | 著者 | Larrieux, N, Gonzalez Bardeci, N, Trajtenberg, F, Buschiazzo, A. | | 登録日 | 2020-07-09 | | 公開日 | 2021-04-14 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | | 主引用文献 | The crystal structure of yeast regulatory subunit reveals key evolutionary insights into Protein Kinase A oligomerization.
J.Struct.Biol., 213, 2021
|
|
8EBF
 | |
4DVH
 | | Crystal structure of Trypanosoma cruzi mitochondrial iron superoxide dismutase | | 分子名称: | FE (III) ION, Superoxide dismutase | | 著者 | Larrieux, N, Buschiazzo, A. | | 登録日 | 2012-02-23 | | 公開日 | 2013-03-27 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | | 主引用文献 | Structural and Molecular Basis of the Peroxynitrite-mediated Nitration and Inactivation of Trypanosoma cruzi Iron-Superoxide Dismutases (Fe-SODs) A and B: DISPARATE SUSCEPTIBILITIES DUE TO THE REPAIR OF TYR35 RADICAL BY CYS83 IN Fe-SODB THROUGH INTRAMOLECULAR ELECTRON TRANSFER.
J.Biol.Chem., 289, 2014
|
|
3OPZ
 | | Crystal structure of trans-sialidase in complex with the Fab fragment of a neutralizing monoclonal IgG antibody | | 分子名称: | 1,4-DIETHYLENE DIOXIDE, SODIUM ION, Trans-sialidase, ... | | 著者 | Larrieux, N, Muia, R, Campetella, O, Buschiazzo, A. | | 登録日 | 2010-09-02 | | 公開日 | 2011-11-09 | | 最終更新日 | 2021-10-06 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Trypanosoma cruzi trans-sialidase in complex with a neutralizing antibody: structure/function studies towards the rational design of inhibitors.
Plos Pathog., 8, 2012
|
|
6O6O
 | | Structure of the regulator FasR from Mycobacterium tuberculosis | | 分子名称: | MYRISTIC ACID, TetR family transcriptional regulator | | 著者 | Larrieux, N, Trajtenberg, F, Lara, J, Gramajo, H, Buschiazzo, A. | | 登録日 | 2019-03-07 | | 公開日 | 2020-03-11 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | Mycobacterium tuberculosis FasR senses long fatty acyl-CoA through a tunnel and a hydrophobic transmission spine.
Nat Commun, 11, 2020
|
|
6O6N
 | | Structure of the regulator FasR from Mycobacterium tuberculosis in complex with C20-CoA | | 分子名称: | Arachinoyl-CoA, CHLORIDE ION, TetR family transcriptional regulator | | 著者 | Larrieux, N, Trajtenberg, F, Lara, J, Gramajo, H, Buschiazzo, A. | | 登録日 | 2019-03-07 | | 公開日 | 2020-03-11 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Mycobacterium tuberculosis FasR senses long fatty acyl-CoA through a tunnel and a hydrophobic transmission spine.
Nat Commun, 11, 2020
|
|
6O6P
 | | Structure of the regulator FasR from Mycobacterium tuberculosis in complex with DNA | | 分子名称: | DNA-forward, DNA-reverse, TetR family transcriptional regulator | | 著者 | Larrieux, N, Trajtenberg, F, Lara, J, Gramajo, H, Buschiazzo, A. | | 登録日 | 2019-03-07 | | 公開日 | 2020-03-11 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.851 Å) | | 主引用文献 | Mycobacterium tuberculosis FasR senses long fatty acyl-CoA through a tunnel and a hydrophobic transmission spine.
Nat Commun, 11, 2020
|
|
5K0W
 | | Crystal structure of the metallo-beta-lactamase GOB-18 from Elizabethkingia meningoseptica | | 分子名称: | CHLORIDE ION, Class B carbapenemase GOB-18, GLYCEROL, ... | | 著者 | Buschiazzo, A, Larrieux, N, Vila, A.J, Lisa, M.N, Moran-Barrio, J. | | 登録日 | 2016-05-17 | | 公開日 | 2016-08-03 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | | 主引用文献 | Crystal Structure of the Metallo-beta-Lactamase GOB in the Periplasmic Dizinc Form Reveals an Unusual Metal Site.
Antimicrob.Agents Chemother., 60, 2016
|
|
5CEE
 | | Malic enzyme from Candidatus Phytoplasma AYWB in complex with NAD and Mg2+ | | 分子名称: | MAGNESIUM ION, NAD-dependent malic enzyme, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | 著者 | Alvarez, C.E, Trajtenberg, F, Larrieux, N, Saigo, M, Mussi, M.A, Andreo, C.S, Drincovich, M.F, Buschiazzo, A. | | 登録日 | 2015-07-06 | | 公開日 | 2016-10-05 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.498 Å) | | 主引用文献 | The crystal structure of the malic enzyme from Candidatus Phytoplasma reveals the minimal structural determinants for a malic enzyme.
Acta Crystallogr D Struct Biol, 74, 2018
|
|
6D24
 | | Trypanosoma cruzi Glucose-6-P Dehydrogenase in complex with G6P | | 分子名称: | 6-O-phosphono-beta-D-glucopyranose, CHLORIDE ION, GLYCEROL, ... | | 著者 | Botti, H, Ortiz, C, Comini, M.A, Larrieux, N, Buschiazzo, A. | | 登録日 | 2018-04-12 | | 公開日 | 2018-05-02 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | | 主引用文献 | Glucose-6-Phosphate Dehydrogenase from the Human Pathogen Trypanosoma cruzi Evolved Unique Structural Features to Support Efficient Product Formation.
J.Mol.Biol., 431, 2019
|
|
6D23
 | | GLUCOSE-6-P DEHYDROGENASE (APO FORM) FROM TRYPANOSOMA CRUZI | | 分子名称: | CHLORIDE ION, GLYCEROL, Glucose-6-phosphate 1-dehydrogenase, ... | | 著者 | Botti, H, Ortiz, C, Comini, M.A, Larrieux, N, Buschiazzo, A. | | 登録日 | 2018-04-12 | | 公開日 | 2018-05-02 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Glucose-6-Phosphate Dehydrogenase from the Human Pathogen Trypanosoma cruzi Evolved Unique Structural Features to Support Efficient Product Formation.
J.Mol.Biol., 431, 2019
|
|
5IUL
 | | Crystal structure of the DesK-DesR complex in the phosphotransfer state with high Mg2+ (150 mM) and BeF3 | | 分子名称: | MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, POTASSIUM ION, ... | | 著者 | Trajtenberg, F, Imelio, J.A, Larrieux, N, Buschiazzo, A. | | 登録日 | 2016-03-18 | | 公開日 | 2016-12-21 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (3.153 Å) | | 主引用文献 | Regulation of signaling directionality revealed by 3D snapshots of a kinase:regulator complex in action.
Elife, 5, 2016
|
|
5IUJ
 | | Crystal structure of the DesK-DesR complex in the phosphotransfer state with low Mg2+ (20 mM) | | 分子名称: | MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, POTASSIUM ION, ... | | 著者 | Trajtenberg, F, Imelio, J.A, Larrieux, N, Buschiazzo, A. | | 登録日 | 2016-03-18 | | 公開日 | 2016-12-21 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Regulation of signaling directionality revealed by 3D snapshots of a kinase:regulator complex in action.
Elife, 5, 2016
|
|
5IUK
 | | Crystal structure of the DesK-DesR complex in the phosphotransfer state with high Mg2+ (150 mM) | | 分子名称: | MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, POTASSIUM ION, ... | | 著者 | Trajtenberg, F, Imelio, J.A, Larrieux, N, Buschiazzo, A. | | 登録日 | 2016-03-18 | | 公開日 | 2016-12-21 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Regulation of signaling directionality revealed by 3D snapshots of a kinase:regulator complex in action.
Elife, 5, 2016
|
|
6OC8
 | |
4LE2
 | |
4LE0
 | | Crystal structure of the receiver domain of DesR in complex with beryllofluoride and magnesium | | 分子名称: | ACETATE ION, BERYLLIUM TRIFLUORIDE ION, GLYCEROL, ... | | 著者 | Trajtenberg, F, Larrieux, N, Buschiazzo, A. | | 登録日 | 2013-06-25 | | 公開日 | 2014-07-16 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | | 主引用文献 | Allosteric activation of bacterial response regulators: the role of the cognate histidine kinase beyond phosphorylation.
MBio, 5, 2014
|
|
4LE1
 | | Crystal structure of the receiver domain of DesR in the inactive state | | 分子名称: | ACETATE ION, GLYCEROL, SULFATE ION, ... | | 著者 | Trajtenberg, F, Larrieux, N, Buschiazzo, A. | | 登録日 | 2013-06-25 | | 公開日 | 2014-07-16 | | 最終更新日 | 2015-05-06 | | 実験手法 | X-RAY DIFFRACTION (1.951 Å) | | 主引用文献 | Allosteric activation of bacterial response regulators: the role of the cognate histidine kinase beyond phosphorylation.
MBio, 5, 2014
|
|
4LDZ
 | | Crystal structure of the full-length response regulator DesR in the active state | | 分子名称: | BERYLLIUM TRIFLUORIDE ION, GLYCEROL, MAGNESIUM ION, ... | | 著者 | Trajtenberg, F, Larrieux, N, Buschiazzo, A. | | 登録日 | 2013-06-25 | | 公開日 | 2014-07-16 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | Allosteric activation of bacterial response regulators: the role of the cognate histidine kinase beyond phosphorylation.
MBio, 5, 2014
|
|
4LS7
 | | Crystal structure of Bacillus subtilis beta-ketoacyl-ACP synthase II (FabF) in a non-covalent complex with cerulenin | | 分子名称: | 3-oxoacyl-[acyl-carrier-protein] synthase 2, Cerulenin, GLYCEROL, ... | | 著者 | Trajtenberg, F, Larrieux, N, Buschiazzo, A. | | 登録日 | 2013-07-22 | | 公開日 | 2014-04-02 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.674 Å) | | 主引用文献 | Structural insights into bacterial resistance to cerulenin.
Febs J., 281, 2014
|
|
4LS8
 | | Crystal structure of Bacillus subtilis beta-ketoacyl-ACP synthase II (FabF) in a covalent complex with cerulenin | | 分子名称: | (3R,7E,10E)-3-hydroxy-4-oxododeca-7,10-dienamide, 1,2-ETHANEDIOL, 3-oxoacyl-[acyl-carrier-protein] synthase 2, ... | | 著者 | Trajtenberg, F, Larrieux, N, Buschiazzo, A. | | 登録日 | 2013-07-22 | | 公開日 | 2014-04-02 | | 最終更新日 | 2014-06-04 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural insights into bacterial resistance to cerulenin.
Febs J., 281, 2014
|
|
4LS5
 | |
4LS6
 | | Crystal structure of beta-ketoacyl-ACP synthase II (FabF) I108F mutant from Bacillus subtilis | | 分子名称: | 3-oxoacyl-[acyl-carrier-protein] synthase 2, CHLORIDE ION, GLYCEROL, ... | | 著者 | Trajtenberg, F, Larrieux, N, Buschiazzo, A. | | 登録日 | 2013-07-22 | | 公開日 | 2014-04-02 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | | 主引用文献 | Structural insights into bacterial resistance to cerulenin.
Febs J., 281, 2014
|
|
6NQY
 | | Flagellar protein FcpA from Leptospira biflexa / ab-centered monoclinic form | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, Flagellar coiling protein A, ... | | 著者 | Mechaly, A, Larrieux, N, Trajtenberg, F, Buschiazzo, A. | | 登録日 | 2019-01-22 | | 公開日 | 2020-01-29 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | An asymmetric sheath controls flagellar supercoiling and motility in the Leptospira spirochete.
Elife, 9, 2020
|
|
6NQX
 | | Flagellar protein FcpA from Leptospira biflexa / primitive monoclinic form | | 分子名称: | Flagellar coiling protein A, GLYCEROL | | 著者 | Mechaly, A, Larrieux, N, Trajtenberg, F, Buschiazzo, A. | | 登録日 | 2019-01-22 | | 公開日 | 2020-01-29 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | An asymmetric sheath controls flagellar supercoiling and motility in the Leptospira spirochete
Elife, 9, 2020
|
|
