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1VET
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BU of 1vet by Molmil
Crystal Structure of p14/MP1 at 1.9 A resolution
Descriptor: Late endosomal/lysosomal Mp1 interacting protein, Mitogen-activated protein kinase kinase 1 interacting protein 1
Authors:Kurzbauer, R, Teis, D, Maurer-Stroh, S, Eisenhaber, F, Hekman, M, Bourenkov, G.P, Bartunik, H.D, Huber, L.A, Clausen, T.
Deposit date:2004-04-05
Release date:2004-08-03
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the p14/MP1 scaffolding complex: How a twin couple attaches mitogen- activated protein kinase signaling to late endosomes
Proc.Natl.Acad.Sci.USA, 101, 2004
1VEU
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BU of 1veu by Molmil
Crystal structure of the p14/MP1 complex at 2.15 A resolution
Descriptor: Late endosomal/lysosomal Mp1 interacting protein, Mitogen-activated protein kinase kinase 1 interacting protein 1
Authors:Kurzbauer, R, Teis, D, Maurer-Stroh, S, Eisenhaber, F, Hekman, M, Bourenkov, G.P, Bartunik, H.D, Huber, L.A, Clausen, T.
Deposit date:2004-04-05
Release date:2004-08-03
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal structure of the p14/MP1 scaffolding complex: How a twin couple attaches mitogen- activated protein kinase signaling to late endosomes
Proc.Natl.Acad.Sci.USA, 101, 2004
2R3U
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BU of 2r3u by Molmil
Crystal structure of the PDZ deletion mutant of DegS
Descriptor: Protease degS
Authors:Clausen, T, Kurzbauer, R.
Deposit date:2007-08-30
Release date:2007-11-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Regulation of the sigmaE stress response by DegS: how the PDZ domain keeps the protease inactive in the resting state and allows integration of different OMP-derived stress signals upon folding stress.
Genes Dev., 21, 2007
4C2H
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BU of 4c2h by Molmil
Crystal structure of the CtpB(V118Y) mutant
Descriptor: CARBOXY-TERMINAL PROCESSING PROTEASE CTPB
Authors:Mastny, M, Heuck, A, Kurzbauer, R, Clausen, T.
Deposit date:2013-08-17
Release date:2013-12-04
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Ctpb Assembles a Gated Protease Tunnel Regulating Cell-Cell Signaling During Spore Formation in Bacillus Subtilis.
Cell(Cambridge,Mass.), 155, 2013
4C2F
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BU of 4c2f by Molmil
Crystal structure of the CtpB R168A mutant present in an active conformation
Descriptor: CARBOXY-TERMINAL PROCESSING PROTEASE CTPB, PEPTIDE1, PEPTIDE2
Authors:Mastny, M, Heuck, A, Kurzbauer, R, Clausen, T.
Deposit date:2013-08-17
Release date:2013-12-04
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Ctpb Assembles a Gated Protease Tunnel Regulating Cell-Cell Signaling During Spore Formation in Bacillus Subtilis.
Cell(Cambridge,Mass.), 155, 2013
4C2E
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BU of 4c2e by Molmil
Crystal structure of the protease CtpB(S309A) present in a resting state
Descriptor: CARBOXY-TERMINAL PROCESSING PROTEASE CTPB
Authors:Mastny, M, Heuck, A, Kurzbauer, R, Clausen, T.
Deposit date:2013-08-17
Release date:2013-12-04
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Ctpb Assembles a Gated Protease Tunnel Regulating Cell-Cell Signaling During Spore Formation in Bacillus Subtilis.
Cell(Cambridge,Mass.), 155, 2013
4C2C
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BU of 4c2c by Molmil
Crystal structure of the protease CtpB in an active state
Descriptor: CARBOXY-TERMINAL PROCESSING PROTEASE CTPB, PEPTIDE1, PEPTIDE2
Authors:Mastny, M, Heuck, A, Kurzbauer, R, Clausen, T.
Deposit date:2013-08-17
Release date:2013-12-04
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Ctpb Assembles a Gated Protease Tunnel Regulating Cell-Cell Signaling During Spore Formation in Bacillus Subtilis.
Cell(Cambridge,Mass.), 155, 2013
4C2D
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BU of 4c2d by Molmil
Crystal structure of the protease CtpB in an active state
Descriptor: CARBOXY-TERMINAL PROCESSING PROTEASE CTPB, PEPTIDE1, PEPTIDE2
Authors:Mastny, M, Heuck, A, Kurzbauer, R, Clausen, T.
Deposit date:2013-08-17
Release date:2013-12-04
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Ctpb Assembles a Gated Protease Tunnel Regulating Cell-Cell Signaling During Spore Formation in Bacillus Subtilis.
Cell(Cambridge,Mass.), 155, 2013
4C2G
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BU of 4c2g by Molmil
Crystal structure of CtpB(S309A) in complex with a peptide having a Val-Pro-Ala C-terminus
Descriptor: CARBOXY-TERMINAL PROCESSING PROTEASE CTPB, PEPTIDE1
Authors:Mastny, M, Heuck, A, Kurzbauer, R, Clausen, T.
Deposit date:2013-08-17
Release date:2013-12-04
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Ctpb Assembles a Gated Protease Tunnel Regulating Cell-Cell Signaling During Spore Formation in Bacillus Subtilis.
Cell(Cambridge,Mass.), 155, 2013
1SOT
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BU of 1sot by Molmil
Crystal Structure of the DegS stress sensor
Descriptor: Protease degS
Authors:Wilken, C, Kitzing, K, Kurzbauer, R, Ehrmann, M, Clausen, T.
Deposit date:2004-03-15
Release date:2004-06-08
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the DegS stress sensor: How a PDZ domain recognizes misfolded protein and activates a protease
Cell(Cambridge,Mass.), 117, 2004
1VCW
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BU of 1vcw by Molmil
Crystal structure of DegS after backsoaking the activating peptide
Descriptor: Protease degS
Authors:Wilken, C, Kitzing, K, Kurzbauer, R, Ehrmann, M, Clausen, T.
Deposit date:2004-03-16
Release date:2004-06-08
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Crystal structure of the DegS stress sensor: How a PDZ domain recognizes misfolded protein and activates a protease.
Cell(Cambridge,Mass.), 117, 2004
1SOZ
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BU of 1soz by Molmil
Crystal Structure of DegS protease in complex with an activating peptide
Descriptor: Protease degS, activating peptide
Authors:Wilken, C, Kitzing, K, Kurzbauer, R, Ehrmann, M, Clausen, T.
Deposit date:2004-03-16
Release date:2004-06-08
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of the DegS stress sensor: How a PDZ domain recognizes misfolded protein and activates a protease
Cell(Cambridge,Mass.), 117, 2004
6TV6
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BU of 6tv6 by Molmil
Octameric McsB from Bacillus subtilis.
Descriptor: MAGNESIUM ION, Protein-arginine kinase
Authors:Suskiewicz, M.J, Hajdusits, B, Meinhart, A, Clausen, T.
Deposit date:2020-01-09
Release date:2021-07-21
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:McsB forms a gated kinase chamber to mark aberrant bacterial proteins for degradation.
Elife, 10, 2021
5HBN
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BU of 5hbn by Molmil
ClpC N-terminal domain with bound phospho-arginine
Descriptor: ACETATE ION, Negative regulator of genetic competence ClpC/MecB, SULFATE ION, ...
Authors:Suskiewicz, M.J, Clausen, T.
Deposit date:2016-01-01
Release date:2016-10-12
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.602 Å)
Cite:Arginine phosphorylation marks proteins for degradation by a Clp protease.
Nature, 539, 2016
5D4W
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BU of 5d4w by Molmil
Crystal structure of Hsp104
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Putative heat shock protein
Authors:Heuck, A, Schitter-Sollner, S, Clausen, T.
Deposit date:2015-08-09
Release date:2016-12-07
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Structural basis for the disaggregase activity and regulation of Hsp104.
Elife, 5, 2016
7BII
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BU of 7bii by Molmil
Crystal structure of Nematocida HUWE1
Descriptor: E3 ubiquitin-protein ligase HUWE1
Authors:Grabarczyk, D.B, Petrova, O.A, Meinhart, A, Kessler, D, Clausen, T.
Deposit date:2021-01-12
Release date:2021-07-28
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.037 Å)
Cite:HUWE1 employs a giant substrate-binding ring to feed and regulate its HECT E3 domain.
Nat.Chem.Biol., 17, 2021
2R3Y
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BU of 2r3y by Molmil
Crystal structure of the DegS protease in complex with the YWF activating peptide
Descriptor: Protease degS, Synthetic peptide YWF
Authors:Clausen, T, Hasselblatt, H.
Deposit date:2007-08-30
Release date:2007-11-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Regulation of the sigmaE stress response by DegS: how the PDZ domain keeps the protease inactive in the resting state and allows integration of different OMP-derived stress signals upon folding stress.
Genes Dev., 21, 2007
6QDJ
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BU of 6qdj by Molmil
Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin
Descriptor: 1,4-BUTANEDIOL, 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Meinhart, A, Clausen, T, Arnese, R.
Deposit date:2019-01-02
Release date:2019-10-30
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.884 Å)
Cite:Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin.
Nat Commun, 10, 2019
3HGS
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BU of 3hgs by Molmil
Crystal structure of tomato OPR3 in complex with pHB
Descriptor: 12-oxophytodienoate reductase 3, FLAVIN MONONUCLEOTIDE, P-HYDROXYBENZOIC ACID
Authors:Clausen, T, Breithaupt, C.
Deposit date:2009-05-14
Release date:2009-08-25
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis of substrate specificity of plant 12-oxophytodienoate reductases.
J.Mol.Biol., 392, 2009
3HGO
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BU of 3hgo by Molmil
Crystal structure of the F74Y/H244Y OPR3 double mutant from tomato
Descriptor: 12-oxophytodienoate reductase 3, FLAVIN MONONUCLEOTIDE
Authors:Clausen, T, Breithaupt, C.
Deposit date:2009-05-14
Release date:2009-08-25
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis of substrate specificity of plant 12-oxophytodienoate reductases.
J.Mol.Biol., 392, 2009
3HGR
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BU of 3hgr by Molmil
Crystal structure of tomato OPR1 in complex with pHB
Descriptor: 12-oxophytodienoate reductase 1, FLAVIN MONONUCLEOTIDE, P-HYDROXYBENZOIC ACID
Authors:Clausen, T, Breithaupt, C.
Deposit date:2009-05-14
Release date:2009-08-25
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis of substrate specificity of plant 12-oxophytodienoate reductases.
J.Mol.Biol., 392, 2009
6QDL
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BU of 6qdl by Molmil
Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin
Descriptor: UNC-45
Authors:Meinhart, A, Clausen, T, Hellerschmied, D.
Deposit date:2019-01-02
Release date:2019-10-30
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.929 Å)
Cite:Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin.
Nat Commun, 10, 2019
6QDK
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BU of 6qdk by Molmil
Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin
Descriptor: UNC-45,UNC-45
Authors:Meinhart, A, Clausen, T, Hellerschmied, D.
Deposit date:2019-01-02
Release date:2019-10-30
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin.
Nat Commun, 10, 2019
6QDM
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BU of 6qdm by Molmil
Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin
Descriptor: UNC-45,UNC-45
Authors:Meinhart, A, Clausen, T, Hellerschmied, D.
Deposit date:2019-01-02
Release date:2019-10-30
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin.
Nat Commun, 10, 2019
6FH1
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BU of 6fh1 by Molmil
Protein arginine kinase McsB in the apo state
Descriptor: 1,2-ETHANEDIOL, FORMIC ACID, IMIDAZOLE, ...
Authors:Suskiewicz, M.J, Heuck, A, Vu, L.D, Clausen, T.
Deposit date:2018-01-12
Release date:2019-02-06
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of McsB, a protein kinase for regulated arginine phosphorylation.
Nat.Chem.Biol., 15, 2019

 

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