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3U2J
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BU of 3u2j by Molmil
Neutron crystal structure of human Transthyretin
Descriptor: Transthyretin
Authors:Yokoyama, T, Mizuguchi, M, Nabeshima, Y, Kusaka, K, Yamada, T, Hosoya, T, Ohhara, T, Kurihara, K, Tomoyori, K, Tanaka, I, Niimura, N.
Deposit date:2011-10-03
Release date:2012-02-22
Last modified:2023-11-01
Method:NEUTRON DIFFRACTION (2 Å)
Cite:Hydrogen-bond network and pH sensitivity in transthyretin: Neutron crystal structure of human transthyretin
J.Struct.Biol., 177, 2012
3U2I
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BU of 3u2i by Molmil
X-ray crystal structure of human Transthyretin at room temperature
Descriptor: Transthyretin
Authors:Yokoyama, T, Mizuguchi, M, Nabeshima, Y, Kusaka, K, Yamada, T, Hosoya, T, Ohhara, T, Kurihara, K, Tomoyori, K, Tanaka, I, Niimura, N.
Deposit date:2011-10-03
Release date:2012-02-22
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Hydrogen-bond network and pH sensitivity in transthyretin: Neutron crystal structure of human transthyretin
J.Struct.Biol., 177, 2012
3J0E
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BU of 3j0e by Molmil
Models for the T. thermophilus ribosome recycling factor and the E. coli elongation factor G bound to the E. coli post-termination complex
Descriptor: 30S ribosomal protein S12, Elongation factor G, Ribosome-recycling factor, ...
Authors:Yokoyama, T, Shaikh, T.R, Iwakura, N, Kaji, H, Kaji, A, Agrawal, R.K.
Deposit date:2011-06-29
Release date:2012-04-25
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (9.9 Å)
Cite:Structural insights into initial and intermediate steps of the ribosome-recycling process.
Embo J., 31, 2012
6IP6
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BU of 6ip6 by Molmil
Cryo-EM structure of the CMV-stalled human 80S ribosome with HCV IRES (Structure iii)
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Yokoyama, T, Shigematsu, H, Shirouzu, M, Imataka, H, Ito, T.
Deposit date:2018-11-02
Release date:2019-05-29
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:HCV IRES Captures an Actively Translating 80S Ribosome.
Mol.Cell, 74, 2019
6IP8
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BU of 6ip8 by Molmil
Cryo-EM structure of the HCV IRES dependently initiated CMV-stalled 80S ribosome (Structure iv)
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Yokoyama, T, Shigematsu, H, Shirouzu, M, Imataka, H, Ito, T.
Deposit date:2018-11-02
Release date:2019-05-29
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:HCV IRES Captures an Actively Translating 80S Ribosome.
Mol.Cell, 74, 2019
6IP5
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BU of 6ip5 by Molmil
Cryo-EM structure of the CMV-stalled human 80S ribosome (Structure ii)
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Yokoyama, T, Shigematsu, H, Shirouzu, M, Imataka, H, Ito, T.
Deposit date:2018-11-02
Release date:2019-05-29
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:HCV IRES Captures an Actively Translating 80S Ribosome.
Mol.Cell, 74, 2019
5H0Z
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BU of 5h0z by Molmil
Crystal structure of P113A mutated human transthyretin
Descriptor: CHLORIDE ION, SULFATE ION, Transthyretin
Authors:Yokoyama, T, Hanawa, Y, Obita, T, Mizuguchi, M.
Deposit date:2016-10-07
Release date:2017-06-14
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.735 Å)
Cite:Stability and crystal structures of His88 mutant human transthyretins
FEBS Lett., 591, 2017
5H0V
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BU of 5h0v by Molmil
Crystal structure of H88A mutated human transthyretin
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, MAGNESIUM ION, Transthyretin
Authors:Yokoyama, T, Hanawa, Y, Obita, T, Mizuguchi, M.
Deposit date:2016-10-07
Release date:2017-06-14
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Stability and crystal structures of His88 mutant human transthyretins
FEBS Lett., 591, 2017
5H0X
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BU of 5h0x by Molmil
Crystal structure of H88S mutated human transthyretin
Descriptor: Transthyretin
Authors:Yokoyama, T, Hanawa, Y, Obita, T, Mizuguchi, M.
Deposit date:2016-10-07
Release date:2017-06-14
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.573 Å)
Cite:Stability and crystal structures of His88 mutant human transthyretins
FEBS Lett., 591, 2017
5H0W
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BU of 5h0w by Molmil
Crystal structure of H88F mutated human transthyretin
Descriptor: SULFATE ION, Transthyretin
Authors:Yokoyama, T, Hanawa, Y, Obita, T, Mizuguchi, M.
Deposit date:2016-10-07
Release date:2017-06-14
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.904 Å)
Cite:Stability and crystal structures of His88 mutant human transthyretins
FEBS Lett., 591, 2017
5H0Y
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BU of 5h0y by Molmil
Crystal structure of H88Y mutated human transthyretin
Descriptor: CHLORIDE ION, SULFATE ION, Transthyretin
Authors:Yokoyama, T, Hanawa, Y, Obita, T, Mizuguchi, M.
Deposit date:2016-10-07
Release date:2017-06-14
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Stability and crystal structures of His88 mutant human transthyretins
FEBS Lett., 591, 2017
3J0D
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BU of 3j0d by Molmil
Models for the T. thermophilus ribosome recycling factor bound to the E. coli post-termination complex
Descriptor: 30S ribosomal protein S12, 50S ribosomal protein L11, Ribosome-recycling factor, ...
Authors:Yokoyama, T, Shaikh, T.R, Iwakura, N, Kaji, H, Kaji, A, Agrawal, R.K.
Deposit date:2011-06-29
Release date:2012-04-25
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (11.1 Å)
Cite:Structural insights into initial and intermediate steps of the ribosome-recycling process.
Embo J., 31, 2012
5AYT
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BU of 5ayt by Molmil
Crystal structure of transthyretin in complex with L6
Descriptor: 2-oxidanyl-6-(phenylcarbonyl)benzo[de]isoquinoline-1,3-dione, Transthyretin
Authors:Yokoyama, T, Mizuguchi, M, Kai, H.
Deposit date:2015-09-03
Release date:2016-01-20
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural stabilization of transthyretin by a new compound, 6-benzoyl-2-hydroxy-1H-benzo[de]isoquinoline-1,3(2H)-dione
J. Pharmacol. Sci., 129, 2015
4PWF
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BU of 4pwf by Molmil
Crystal structure of V30M mutant human transthyretin complexed with ferulic acid phenethyl ester
Descriptor: 2-phenylethyl (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate, Transthyretin
Authors:Yokoyama, T, Kosaka, Y, Mizuguchi, M.
Deposit date:2014-03-20
Release date:2014-11-26
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Inhibitory Activities of Propolis and Its Promising Component, Caffeic Acid Phenethyl Ester, against Amyloidogenesis of Human Transthyretin
J.Med.Chem., 57, 2014
4PWH
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BU of 4pwh by Molmil
Crystal structure of V30M mutant human transthyretin complexed with caffeic acid 1,1-dimethylallyl ester
Descriptor: 3-methylbut-2-en-1-yl (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoate, CALCIUM ION, Transthyretin
Authors:Yokoyama, T, Kosaka, Y, Mizuguchi, M.
Deposit date:2014-03-20
Release date:2014-11-26
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.798 Å)
Cite:Inhibitory Activities of Propolis and Its Promising Component, Caffeic Acid Phenethyl Ester, against Amyloidogenesis of Human Transthyretin
J.Med.Chem., 57, 2014
4PWI
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BU of 4pwi by Molmil
Crystal structure of V30M mutant human transthyretin complexed with rosmarinic acid
Descriptor: (2R)-3-(3,4-dihydroxyphenyl)-2-{[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}propanoic acid, Transthyretin
Authors:Yokoyama, T, Kosaka, Y, Mizuguchi, M.
Deposit date:2014-03-20
Release date:2014-11-26
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.494 Å)
Cite:Inhibitory Activities of Propolis and Its Promising Component, Caffeic Acid Phenethyl Ester, against Amyloidogenesis of Human Transthyretin
J.Med.Chem., 57, 2014
4PWE
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BU of 4pwe by Molmil
Crystal structure of V30M mutant human transthyretin
Descriptor: Transthyretin
Authors:Yokoyama, T, Kosaka, Y, Mizuguchi, M.
Deposit date:2014-03-20
Release date:2014-11-26
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Inhibitory Activities of Propolis and Its Promising Component, Caffeic Acid Phenethyl Ester, against Amyloidogenesis of Human Transthyretin
J.Med.Chem., 57, 2014
4PWJ
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BU of 4pwj by Molmil
Crystal structure of V30M mutant human transthyretin complexed with nordihydroguaiaretic acid
Descriptor: 4-[(2R,3S)-3-[(3,4-DIHYDROXYPHENYL)METHYL]-2-METHYLBUTYL]BENZENE-1,2-DIOL, Transthyretin
Authors:Yokoyama, T, Kosaka, Y, Mizuguchi, M.
Deposit date:2014-03-20
Release date:2014-11-26
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Inhibitory Activities of Propolis and Its Promising Component, Caffeic Acid Phenethyl Ester, against Amyloidogenesis of Human Transthyretin
J.Med.Chem., 57, 2014
4PWG
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BU of 4pwg by Molmil
Crystal structure of V30M mutant human transthyretin complexed with caffeic acid ethyl ester
Descriptor: CALCIUM ION, Transthyretin, ethyl (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoate
Authors:Yokoyama, T, Kosaka, Y, Mizuguchi, M.
Deposit date:2014-03-20
Release date:2014-11-26
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.798 Å)
Cite:Inhibitory Activities of Propolis and Its Promising Component, Caffeic Acid Phenethyl Ester, against Amyloidogenesis of Human Transthyretin
J.Med.Chem., 57, 2014
4PWK
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BU of 4pwk by Molmil
Crystal structure of V30M mutant human transthyretin complexed with dihydroguaiaretic acid
Descriptor: 4,4'-[(2R,3R)-2,3-dimethylbutane-1,4-diyl]bis(2-methoxyphenol), Transthyretin
Authors:Yokoyama, T, Kosaka, Y, Mizuguchi, M.
Deposit date:2014-03-20
Release date:2014-11-26
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Inhibitory Activities of Propolis and Its Promising Component, Caffeic Acid Phenethyl Ester, against Amyloidogenesis of Human Transthyretin
J.Med.Chem., 57, 2014
4QRF
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BU of 4qrf by Molmil
Crystal structure of V30M mutant human transthyretin complexed with caffeic acid phenethyl ester
Descriptor: 2-phenylethyl (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoate, Transthyretin
Authors:Yokoyama, T, Kosaka, Y, Mizuguchi, M.
Deposit date:2014-06-30
Release date:2014-11-26
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Inhibitory Activities of Propolis and Its Promising Component, Caffeic Acid Phenethyl Ester, against Amyloidogenesis of Human Transthyretin
J.Med.Chem., 57, 2014
4N85
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BU of 4n85 by Molmil
Crystal structure of human transthyretin
Descriptor: CALCIUM ION, Transthyretin
Authors:Yokoyama, T, Kosaka, Y, Mizuguchi, M.
Deposit date:2013-10-17
Release date:2014-02-19
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structures of human transthyretin complexed with glabridin
J.Med.Chem., 57, 2014
4N86
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BU of 4n86 by Molmil
Crystal structure of human transthyretin complexed with glabridin
Descriptor: 4-[(3R)-8,8-dimethyl-3,4-dihydro-2H,8H-pyrano[2,3-f]chromen-3-yl]benzene-1,3-diol, CALCIUM ION, Transthyretin
Authors:Yokoyama, T, Kosaka, Y, Mizuguchi, M.
Deposit date:2013-10-17
Release date:2014-02-19
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Crystal structures of human transthyretin complexed with glabridin
J.Med.Chem., 57, 2014
4N87
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BU of 4n87 by Molmil
Crystal structure of V30M mutant human transthyretin complexed with glabridin
Descriptor: 4-[(3R)-8,8-dimethyl-3,4-dihydro-2H,8H-pyrano[2,3-f]chromen-3-yl]benzene-1,3-diol, Transthyretin
Authors:Yokoyama, T, Kosaka, Y, Mizuguchi, M.
Deposit date:2013-10-17
Release date:2014-02-19
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.794 Å)
Cite:Crystal structures of human transthyretin complexed with glabridin
J.Med.Chem., 57, 2014
8W42
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BU of 8w42 by Molmil
X-ray crystal structure of V30M-TTR in complex with resveratrol
Descriptor: RESVERATROL, SODIUM ION, Transthyretin
Authors:Yokoyama, T.
Deposit date:2023-08-23
Release date:2023-11-22
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Resveratrol Derivatives Inhibit Transthyretin Fibrillization: Structural Insights into the Interactions between Resveratrol Derivatives and Transthyretin.
J.Med.Chem., 66, 2023

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