8IG1

Crystal structure of wild-type transthyretin in complex with rafoxanide

Summary for 8IG1

Entry DOI	10.2210/pdb8ig1/pdb
Descriptor	Transthyretin, ~{N}-[3-chloranyl-4-(4-chloranylphenoxy)phenyl]-3,5-bis(iodanyl)-2-oxidanyl-benzamide, SODIUM ION, ... (4 entities in total)
Functional Keywords	t4 carrier, transporter, amyloidosis, transferase
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	35919.04
Authors	Yokoyama, T. (deposition date: 2023-02-20, release date: 2023-08-16, Last modification date: 2023-11-15)
Primary citation	Yokoyama, T.,Mizuguchi, M.,Nabeshima, Y.,Nakagawa, Y.,Okada, T.,Toyooka, N.,Kusaka, K. Rafoxanide, a salicylanilide anthelmintic, interacts with human plasma protein transthyretin. Febs J., 290:5158-5170, 2023 Cited by PubMed: 37522420 DOI: 10.1111/febs.16915 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.451 Å)

Structure validation